Cation involvement in telomestatin binding to g-quadruplex DNA [0.03%]
telomestatin结合G-四链体DNA的阳离子参与作用
Frédéric Rosu,Valérie Gabelica,Nicolas Smargiasso et al.
Frédéric Rosu et al.
The binding mode of telomestatin to G-quadruplex DNA has been investigated using electrospray mass spectrometry, by detecting the intact complexes formed in ammonium acetate. The mass measurements show the incorporation of one extra ammoniu...
Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes [0.03%]
盐浓度对四苯并卟啉二亚胺环金属衍生物与MyC和BCL2启动区形成的G-四聚体DNA相互作用的影响
Narayana Nagesh,Varun K Sharma,A Ganesh Kumar et al.
Narayana Nagesh et al.
C-myc and Bcl2 are well characterized oncogenes that are capable of forming G-quadruplex structures. Promoter regions of C-myc and Bcl2 forming G-quadruplex structures are chemically synthesized and G-quadruplex structure is formed in prese...
Expression levels of some antioxidant and epidermal growth factor receptor genes in patients with early-stage non-small cell lung cancer [0.03%]
早期非小细胞肺癌患者中一些抗氧化及表皮生长因子受体基因的表达水平
Giuseppe De Palma,Paola Mozzoni,Olga Acampa et al.
Giuseppe De Palma et al.
THIS STUDY WAS AIMED AT: (i) investigating the expression profiles of some antioxidant and epidermal growth factor receptor genes in cancerous and unaffected tissues of patients undergoing lung resection for non-small cell lung cancer (NSCL...
Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties [0.03%]
含胍基和胺官能团侧链的巨环六亚甲基氧化唑（6OTD）二聚体的合成及其对端粒G4稳定性的评价研究论文标题翻译
Keisuke Iida,Masayuki Tera,Takatsugu Hirokawa et al.
Keisuke Iida et al.
Structure-activity relationship studies were carried out on macrocyclic hexaoxazole (6OTD) dimers, whose core structure stabilizes telomeric G-quadruplexes (G4). Two new 6OTD dimers having side chain amine and guanidine functional groups we...
Design, synthesis, and analysis of minor groove binder pyrrolepolyamide-2'-deoxyguanosine hybrids [0.03%]
杂环丙烯亚胺-2'-脱氧鸟苷衍生物的设计、合成及分析研究
Etsuko Kawashima,Yusuke Ohba,Yusuke Terui et al.
Etsuko Kawashima et al.
Pyrrolepolyamide-2'-deoxyguanosine hybrids (Hybrid 2 and Hybrid 3) incorporating the 3-aminopropionyl or 3-aminopropyl linker were designed and synthesized on the basis of previously reported results of a pyrrolepolyamide-adenosine hybrid (...