Long-Term Macrolides in Chronic Respiratory Diseases: Dusk or a New Dawn? A Narrative Review [0.03%]
长期使用大环内酯治疗慢性呼吸系统疾病：黄昏还是黎明？叙事综述
Daniele Previtero,Gioele Castelli,Ylenia Padrin et al.
Daniele Previtero et al.
Macrolides-especially azithromycin-have been increasingly investigated in chronic respiratory diseases for their combined antimicrobial, anti-inflammatory, and immunomodulatory properties. Randomized controlled trials have demonstrated sign...
Chemical Diversity and Ecological Origins of Anti-MRSA Metabolites from Actinomycetota [0.03%]
放线菌门抗MRSA代谢物的化学多样性及生态起源
Sayoane Pessoa Fernandes,Luana Layse Câmara de Almeida,Thalisson Amorim de Souza et al.
Sayoane Pessoa Fernandes et al.
Antimicrobial resistance (AMR) poses a major global threat to human health. Among multidrug-resistant pathogens, MRSA is a leading cause of severe nosocomial infections, urgently demanding the discovery of novel antimicrobial agents. Nature...
Genomic Characterization and Antimicrobial Resistance Profile of Streptococcus uberis Strains Isolated from Cows with Mastitis from Northwestern Spain [0.03%]
来自西班牙西北部患乳腺炎奶牛的乳房中分离出的乳房链球菌基因组特征及抗微生物药物作用性质研究
Emiliano J Quinto,Paz Redondo Del Río,Beatriz de Mateo Silleras et al.
Emiliano J Quinto et al.
Background/Objectives: Streptococcus uberis is a Gram-positive bacterium and a major cause of bovine mastitis. The use of antimicrobial treatments raises concerns about resistance. This study aimed to characterize S. uberis isolates from on...
City or Suburb, Resistance Flows: Wastewater-Borne ESKAPE and AMR Genes in Malaysian Hospitals [0.03%]
城中还是郊外，反抗力都在流淌：马来西亚医院污水中的ESKAPE及抗药基因群
Sophia Karen Bakon,Nur Fatihah Sholehah Zakaria,Mohd Azerulazree Jamilan et al.
Sophia Karen Bakon et al.
Background/objectives: Hospital wastewater has become a major hotspot for the spread of antimicrobial resistance and the accumulation of antibiotic-resistant genes. We focused on ESKAPE pathogens isolated from hospital wa...
Cefiderocol Comparative Resistance and Clinical Predictors in CRE-BSI: Data from an OXA-48-Endemic Region with Rising OXA-48/NDM Coproducers [0.03%]
头孢迪罗对OXA-48型新德里金属β内酰胺酶（NDM）复合产酶耐甲氧西林的大肠杆菌和 Klebsiella 菌血症的比较抗性及临床预测因素：来自一个以OXA-48为主的流行区域，且 OXA-48/NDM 复合产酶上升地区的数据
Rıdvan Dumlu,Ali Mert
Rıdvan Dumlu
Background/Objectives: Bloodstream infections (BSIs) caused by carbapenem-resistant Enterobacterales (CREs) are a growing public health threat due to limited therapeutic options and high mortality. In Turkey, oxacillinase-48 (OXA-48) produc...
Identification of the Genetic Basis of Phage Resistance in Sequentially Generated Phage-Resistant Klebsiella pneumoniae Using an Established Phage Library [0.03%]
利用已建立的噬菌体库鉴定逐次出现的肺炎克雷伯氏菌噬菌体抗性株的遗传基础
Wenbo Zhao,Congyang Du,Zheng Chen et al.
Wenbo Zhao et al.
Objectives: To explore the genetic basis of phage resistance in sequentially generated capsular mutants of phage-resistant Klebsiella pneumoniae using an established phage library. Methods: Sequential induction strategies were employed to o...
Tourism and the Global Vectoring of Antimicrobial-Resistant Disease: What Countries Are Most Impacted? [0.03%]
旅游和全球抗菌药物耐药性疾病传播：哪些国家受到的影响最大？
Peter Collignon,John J Beggs
Peter Collignon
Background: Tourists returning home and visitors from abroad often carry antimicrobial-resistant (AMR) bacteria. Many of these resistant bacteria are acquired from, or were spread via, the environment (especially water). Understanding the i...
Antibiotic Alternatives and Next-Generation Therapeutics for Salmonella Control: A One Health Approach to Combating Antimicrobial Resistance [0.03%]
抗菌替代品及下一代疗法在沙门氏菌控制中的应用——基于大健康理念的抗微生物药物耐药性防控措施
Mohamed Saleh,Ashutosh Verma,Khaled A Shaaban et al.
Mohamed Saleh et al.
The growing prevalence of antimicrobial resistance has significantly compromised the efficacy of conventional antibiotic-based interventions in controlling Salmonella infections across human and veterinary settings. This growing challenge n...
Comparison of Phenotypic and Whole-Genome Sequencing-Derived Antimicrobial Resistance Profiles of Legionella pneumophila Isolated in England and Wales from 2020 to 2023 [0.03%]
2020年至2023年在英格兰和威尔士分离的Legionella pneumophila表型和全基因组测序衍生的抗菌药物耐药谱比较
Rediat Tewolde,Rebecca Thombre,Caitlin Farley et al.
Rediat Tewolde et al.
Background: Antimicrobial resistance (AMR) in Legionella pneumophila is emerging as a concern, particularly with resistance to macrolides and fluoroquinolones. Although clinically significant resistance in Legionella pneumophila remains unc...
Gemmotherapy Extracts Like the Dog Rose, Lingonberry, Sea Buckthorn, Blackthorn, Common Grape, Hawthorn, Raspberry and Boxwood Feature Variable Yet Excelling Antimicrobial Effects [0.03%]
野生植物愈创提取物具有多種且出色的抗菌效果：山蔷薇、 lingonberry、沙棘、黑索金、葡萄、山楂、覆盆子和BOXWOOD为例
Melinda Héjja,Éva György,Ferenc Ádám Lóga et al.
Melinda Héjja et al.
Background: Antibiotic resistance is spreading, and the effectiveness of the most widely used antibiotics is decreasing. These issues are global health and food safety concerns that require immediate attention. One potential solution is the...