Comparative Analysis of Methicillin-Susceptible Staphylococcus aureus and Streptococcal Native Joint Septic Arthritis: Clinical Characteristics and Outcomes [0.03%]
金黄色葡萄球菌和链球菌性化脓性关节炎的临床特点及预后分析
Jungok Kim,Eun-Jeong Joo,Ki-Ho Park et al.
Jungok Kim et al.
Background/Objectives: This study aimed to evaluate and compare the clinical characteristics and outcomes of patients with methicillin-susceptible Staphylococcus aureus (MSSA) and streptococcal native joint septic arthritis (NJSA). Methods:...
Molecular Characterisation and Descriptive Analysis of Carbapenemase-Producing Enterobacterales: Striking Epidemiological Changes [0.03%]
碳青霉烯耐药肠杆菌科细菌分子表型特征及描述性流行病学分析：显著的疫情变化趋势
Estíbaliz Ugalde Zárraga,Matxalen Vidal-García,Mikel Urrutikoetxea-Gutiérrez et al.
Estíbaliz Ugalde Zárraga et al.
Background/Objectives: Klebsiella pneumoniae complex, Escherichia coli, and Enterobacter cloacae complex are considered the most prevalent carbapenemase-producing (CP) Enterobacterales in Spain. However, temporal changes in carbapenemase di...
Skin Infection Pathogenicity Associated with a Canine Microbiome Resident: Polygenic Architecture of Virulence Factors in Staphylococcus pseudintermedius [0.03%]
与犬类微生物群系居民相关的皮肤感染病原性：中间葡萄球菌毒力因子的多基因结构
Aqib Javaid,Nazia Tabassum,Abirami Karthikeyan et al.
Aqib Javaid et al.
Staphylococcus pseudintermedius is a common opportunistic pathogen in companion animals and a leading cause of skin and soft tissue infections (SSTIs). Despite its clinical relevance, the genomic determinants underlying pathogenicity and th...
Ranalexin-1G: A Promising Antimicrobial Peptide Targeting Virulence and Host-Pathogen Interactions in Pseudomonas aeruginosa In Vitro Models [0.03%]
Ranalexin-1G：一种针对铜绿假单胞菌致病性和宿主-病原体相互作用的抗菌肽（体外模型）
Marina Acunzo,Carla Zannella,Rosa Giugliano et al.
Marina Acunzo et al.
Background: Lung infections represent a major cause of morbidity and mortality in patients with cystic fibrosis (CF) and are predominantly associated with chronic infection by Pseudomonas aeruginosa. The clinical manageme...
Current Recommendations, Antibiotic Resistance, and Emerging Treatments for Gram-Positive Ocular Infections in the United States [0.03%]
美国当前的推荐意见、抗生素耐药性及革兰阳性眼内感染新兴治疗措施
Inès Fenniri,Camille André
Inès Fenniri
Severe bacterial keratitis and endophthalmitis are leading causes of corneal scarring, enucleation, and permanent vision loss, and are increasingly complicated by multidrug-resistant Gram-positive ocular pathogens. In the United States, acc...
Occurrence of Phenotypic Multidrug-Resistant E. coli in Kentucky (USA) Surface Waters and Exploration of Sentinel Antibiotics for One Health Surveillance [0.03%]
美国肯塔基州地表水中耐多药表型大肠杆菌的出现及“同一健康”监测哨点抗生素的选择研究
Jason W Marion,S Travis Altheide
Jason W Marion
Background/Objectives: Antimicrobial resistance (AMR) is a global public health threat, and surface waters may serve as surveillance locations for multidrug-resistant (MDR) bacteria within communities. This study explored MDR E. coli in Ken...
Physicochemical Stability of Aztreonam/Avibactam in Elastomeric Devices for Outpatient Parenteral Antimicrobial Therapy [0.03%]
氨曲南/阿维巴坦在外院抗微生物治疗弹性装置中的理化稳定性
Cristina Toro Blanch,Xabier Larrea Urtaran,Raquel Aguilar Salmerón et al.
Cristina Toro Blanch et al.
Background/objectives: Outpatient Parenteral Antimicrobial Therapy (OPAT) programs provide a safe and cost-effective strategy for administering intravenous antimicrobials in the home setting. Aztreonam/avibactam (ATM/AVI)...
Suppression of Quorum Sensing and Virulence Factors by Meloxicam and Celecoxib in Methicillin-Resistant Staphylococcus aureus Clinical Isolates [0.03%]
美洛昔康和塞来昔布抑制金黄色葡萄球菌临床分离株的群体感应及毒力因子
Reham Ali,Ramadan A El-Domany,Mona I Shaaban
Reham Ali
Background:Staphylococcus aureus is a major cause of life-threatening infections, and increasing antimicrobial resistance necessitates alternative therapeutic strategies. This study evaluated the antiquorum sensing and antivirulence activit...
Changes in the Gut Microbiome Following Perioperative Prophylactic Cefazolin Administration in Patients Undergoing Orthopedic Surgery: A Longitudinal Prospective Study [0.03%]
围术期预防使用头孢唑林的骨科手术患者肠道菌群的纵向变化：一项前瞻性研究
Dokyun Kim,Woo-Suk Lee,Kyoung Hwa Lee et al.
Dokyun Kim et al.
Introduction: Cefazolin is a first-generation cephalosporin with a moderate antimicrobial spectrum and the ability to induce the production of beta-lactamases by bacterial hosts. We investigated the effect of prophylactic...
Biofilm Formation and the Pore Proteins ompF and ompC Lead to Heteroresistance in Escherichia coli [0.03%]
大肠杆菌生物被膜形成及ompF和ompC孔蛋白导致异质性耐药性现象产生
Jiaojiao Gao,Yating Wu,Xianlan Ma et al.
Jiaojiao Gao et al.
Escherichia coli (E. coli) is a major pathogen responsible for mastitis and calf diarrhea in dairy cows and has developed heteroresistance (HR) to a wide range of antibiotics. An increasing number of animal studies have shown that the prese...