Risk Factors and Outcomes of Early-Onset Sepsis in Very Preterm Infants: Results from the Thai Neonatal Registry (ThaiNy) [0.03%]
泰国早产儿早期败血症的危险因素及结局：来自泰国新生儿注册中心的数据分析结果
Junya Jirapradittha,Dissajee Lumbiganon,Anucha Thatrimontrichai et al.
Junya Jirapradittha et al.
Objective: To determine the incidence, causative pathogens, risk factors, and clinical outcomes of early-onset sepsis (EOS) in very preterm (gestational age < 32 weeks) and very low birth weight (birth weight < 1500 g) ne...
Helicobacter pylori Eradication in the Era of Antibiotic Resistance: From Universal Regimens to Precision-Guided Management [0.03%]
抗生素耐药时代的幽门螺杆菌根除：从普适方案到精准治疗
Ayman Elbehiry,Eman Marzouk
Ayman Elbehiry
Helicobacter pylori (H. pylori) infection represents a major global health challenge and a leading cause of peptic ulcer disease and gastric cancer. The increasing prevalence of antimicrobial resistance has progressively reduced the effecti...
Antimicrobial Stewardship in Vancomycin-Resistant Enterococcus faecalis: Clinical Study Evaluating Antimicrobial Susceptibility Patterns and Antibacterial Regimens [0.03%]
万古霉素耐药屎肠球菌的抗菌药物管理：一项评估抗菌药物敏感性模式和抗生素治疗方案的临床研究
Samantha A Tolbert,Mollie V Day,Aline Arif et al.
Samantha A Tolbert et al.
Background: Vancomycin-resistant enterococci (VRE) Enterococcus faecalis (E. faecalis) remains largely ampicillin-susceptible, yet broad-spectrum agents are frequently used empirically (i.e., daptomycin and linezolid). Despite its frequent ...
Identifying Distinct Antibiotic Behavioural Profiles in Singapore's General Population: A Latent Class Analysis [0.03%]
新加坡居民抗生素行为特征的分类分析
Huiling Guo,Angela Chow
Huiling Guo
Background: Inappropriate antibiotic use for upper respiratory tract infections (URTIs) is common. However, existing research typically examines single indicators or broad categories of misuse practices, without consideri...
Contextual Determinants of Clinical Pharmacists' Contributions to Team-Based Antimicrobial Stewardship in Jordanian Hospitals: A Realist-Informed Qualitative Study [0.03%]
约旦医院临床药剂师在基于团队的抗菌药物管理中的作用及其决定因素：一种现实主义定性研究视角
Mona Bustami,Saba Ammar Alabdali,Mohammad Abu Assab et al.
Mona Bustami et al.
Background/objectives: Clinical pharmacists contribute pharmacotherapy expertise to antimicrobial stewardship (AMS), but antimicrobial prescribing remains a multidisciplinary process led by treating clinicians. In physici...
Antimicrobial Resistance Across the Urban Wastewater Continuum: A One Health Assessment Using High-Throughput qPCR [0.03%]
基于高通量定量 PCR 的城市污水链中抗菌素耐药性的“同一健康”评估
Douha Shouqair,Rashed Alghafri,Subham Verma et al.
Douha Shouqair et al.
Background: Wastewater systems provide an integrated One Health perspective on antimicrobial resistance but remain uneven globally, with limited data from rapidly urbanizing and highly connected regions such as the Arabian Gulf. Methods: An...
Molecular Characterization of Multidrug-Resistant Escherichia coli Isolated from Beef and Chicken Meat Products in Samsun, Türkiye [0.03%]
土耳其萨姆松牛肉和鸡肉产品中多重耐药的大肠杆菌的分子特征分析
Goknur Terzi Gulel,Sibel Kanat,Esra Ekizceli
Goknur Terzi Gulel
Background: Foodborne pathogenic Escherichia coli is a major public health concern due to its frequent association with meat and meat products and its potential to harbor virulence factors and antimicrobial resistance (AMR) determinants. Ob...
Cefiderocol Susceptibility in Japanese Clinical Enterobacterales Isolates and the Effect of IMP-Type Carbapenemases on Resistance [0.03%]
头孢迪洛对日本临床分离的肠杆菌目细菌的体外抗菌活性及其对IMPERIAL型碳青霉烯酶的影响
Manke Cai,Go Yamamoto,Shigeto Hamaguchi et al.
Manke Cai et al.
Objectives: Carbapenem-resistant Enterobacterales (CRE) limit treatment options, and cefiderocol's efficacy can be compromised by regional carbapenemases. In this study, we aimed to characterize cefiderocol susceptibility distribution among...
A Decision-Oriented Calibrated Screening Workflow for Tylosin Derivatives: Closed-Loop MIC Validation Against Staphylococcus aureus and Streptococcus agalactiae [0.03%]
泰乐菌素衍生物的决策导向型校准筛选工作流程：针对金黄色葡萄球菌和杆菌的闭合循环MIC验证
Huan Liu,Yiming Liu,Na Yu et al.
Huan Liu et al.
Background: Antimicrobial resistance among Gram-positive veterinary pathogens has increased the need for more rational and experimentally grounded strategies to prioritize tylosin derivatives for antibacterial development. This study aimed ...
Activity of Corallopyronin A Against ESKAPEE Pathogens: Potential and Translational Implications [0.03%]
一种名为Corallopyronin A的化合物对抗ESKAPE病原体的作用：潜力及转化意义
Jennifer M Colquhoun,Kara W Marshall,Miriam Grosse et al.
Jennifer M Colquhoun et al.
Background: Corallopyronin A (CorA) is a bacterial RNA polymerase inhibitor that binds a site distinct from rifamycins, but its activity across the ESKAPEE pathogen panel and its translational potential remain incompletely defined. Methods:...