Time-Dependent Degradation of Imipenem in Aqueous Solution and Its Impact on Antibacterial Activity [0.03%]
亚胺培南在水溶液中时间依赖性的降解及其对杀菌活性的影响
Gu Hae Kim,Na Rae Kang,Jisoo Kang et al.
Gu Hae Kim et al.
Background/Objectives: Imipenem, known as a carbapenem, is widely used in combination with Cilastatin to treat severe bacterial infections. Imipenem is a β-lactam antibiotic with potent antibacterial activity but a relatively unstable chem...
Combination-Based Biofunctional Coatings for Veterinary Biofilm-Associated Infections [0.03%]
用于兽医生物膜相关感染的组合功能涂层
Muhammad Hassan Khalid,Bilal Aslam,Sulaiman F Aljasir
Muhammad Hassan Khalid
Biofilm-associated infections present a significant but insufficiently acknowledged problem in veterinary medicine because they result in persistent infections that lead to unsuccessful treatments and drive the growth of antimicrobial resis...
Phospholipid-Coated Fe3O4 Nanoparticles Enable Rapid Screening of Putative Antimicrobial Peptides from Clanis bilineata tsingtauica Hemolymph [0.03%]
四氧化三铁磷脂复合纳米颗粒快速筛选中华虎甲血淋巴抗菌肽
Zong-Nan Li,Lei Qian,Qing-Yi Li et al.
Zong-Nan Li et al.
Background/Objectives: Antimicrobial peptides (AMPs) in insect hemolymph are promising alternatives to conventional antibiotics, but their rapid screening from complex biological matrices remains difficult. This study aimed to develop a sim...
Emerging Cross-Resistance to Cefiderocol and Ceftazidime-Avibactam in KPC-Producing Klebsiella pneumoniae During Ceftazidime-Avibactam Therapy [0.03%]
耐碳青霉烯肺炎克雷伯菌(KPC-Kp)株在头孢他啶-阿维巴坦治疗过程中出现新型交叉耐药性：病例报告及体外研究
Cristina Riazzo,Cristina Elías-López,Montserrat Muñoz-Rosa et al.
Cristina Riazzo et al.
Background/Objectives: Ceftazidime-avibactam (CAZ/AVI) and cefiderocol (FDC) retain activity against most clinical isolates of KPC-producing Klebsiella pneumoniae (KPC-Kp). Nevertheless, the emergence of cross-resistance between both agents...
High Antimicrobial Consumption, Low Reported Infection Rates: An Ecological Analysis of HAI Surveillance Discordance Across EU/EEA Countries [0.03%]
高抗菌药物消耗量与低感染率报道：欧盟/欧洲经济区国家HAI监测不一致的生态学分析
Adriana Tatomirescu,Liviu Florian Tatomirescu,Suzana Turcu et al.
Adriana Tatomirescu et al.
Background/Objectives: Healthcare-associated infections (HAI) affect an estimated 4.3 million patients annually in EU/EEA hospitals; yet, reported prevalence rates vary nearly fivefold across member states, a degree of variation inconsisten...
Emerging Global Patterns of Terbinafine Resistance in Trichophyton Species: A Systematic Review and Meta-Analysis [0.03%]
特比萘芬抗性皮肤丝状菌的全球流行趋势：系统评价和meta分析
Imdat Kilbas,Elmas Pinar Kahraman Kilbas,Ihsan Hakki Ciftci et al.
Imdat Kilbas et al.
Background/Objectives: In recent years, reports regarding terbinafine resistance in Trichophyton spp. have increased. The aim of this study is to evaluate the prevalence of terbinafine resistance in Trichophyton spp. species on a regional a...
Effect of Structural Trimming on the Therapeutic Efficacy of K2 Capsule Depolymerase's Klebsiella pneumoniae Phage B1 [0.03%]
结构简化对肺炎克雷伯菌噬菌体B1裂解酶K2胶囊降解酶的治疗效果的影响
György Schneider,Sanjukta Patra,Karl Learmont et al.
György Schneider et al.
Background/Objectives: The treatment of multidrug-resistant and hypervirulent Klebsiella pneumoniae is one of today's biggest healthcare challenges. The depletion of therapeutic options necessities the application of new methods. One promis...
Phage-Derived Endolysins Targeting Cutibacterium acnes: A Scoping Review [0.03%]
针对Cutibacterium acnes的噬菌体衍生内溶酶：一项范围审查
Magdalena Sołtys,Rafał Kuczma,Katarzyna Jermakow et al.
Magdalena Sołtys et al.
Background: Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit in which Cutibacterium acnes plays an important role in disease pathogenesis. Rising antimicrobial resistance has intensified interest in selective antim...
Integrated Genome Mining, Bacterial Co-Culture Activation, and Peptidomic Analyses Identify Antimicrobial Peptide Candidates from South American Bacteria [0.03%]
整合基因组采矿、细菌共培养激活及肽组分析鉴定来自南美细菌的抗菌候选多肽
Abraham Espinoza-Culupú,Samantha Rubio Vasquez,Irving Vílchez Toribio et al.
Abraham Espinoza-Culupú et al.
Background/Objectives: Antimicrobial resistance (AMR) is a major global health threat that requires the discovery of new antimicrobial agents. Environmental microbiomes from understudied regions represent a valuable source of antimicrobial ...
Susceptibility of Staphylococcus aureus Strains Isolated from Blood Cultures Between 2024 and 2025: A Single-Center Study [0.03%]
2024至2025年血培养分离出的金黄色葡萄球菌株的耐药性：一项单中心研究
Victoria Birlutiu,Olteanu Ciprian Ion,Rares-Mircea Birlutiu
Victoria Birlutiu
Background: Staphylococcus aureus bloodstream infection remains a major clinical challenge because of its association with invasive disease, antimicrobial resistance, biofilm formation, and substantial mortality. Local su...