Ultrashort Echo Time and Fast Field Echo Imaging for Spine Bone Imaging with Application in Spondylolysis Evaluation [0.03%]
脊柱骨成像的超短回波时间和快速场回波成像在腰椎峡部裂中的应用价值研究
Diana Vucevic,Vadim Malis,Yuichi Yamashita et al.
Diana Vucevic et al.
Isthmic spondylolysis is characterized by a stress injury to the pars interarticularis bones of the lumbar spines, often missed by conventional magnetic resonance imaging (MRI) necessitating a computed tomography (CT) for accurate diagnosis...
Mathematical Modeling of SARS-CoV-2 Omicron Wave under Vaccination Effects [0.03%]
疫苗影响下数学模型研究SARS-CoV-2奥密克戎毒株传播规律
Gilberto González-Parra,Abraham J Arenas
Gilberto González-Parra
Over the course of the COVID-19 pandemic millions of deaths and hospitalizations have been reported. Different SARS-CoV-2 variants of concern have been recognized during this pandemic and some of these variants of concern have caused uncert...
Design of Inhibitors That Target the Menin-Mixed-Lineage Leukemia Interaction [0.03%]
靶向MENIN-MLL相互作用的抑制剂的设计
Moses N Arthur,Kristeen Bebla,Emmanuel Broni et al.
Moses N Arthur et al.
The prognosis of mixed-lineage leukemia (MLL) has remained a significant health concern, especially for infants. The minimal treatments available for this aggressive type of leukemia has been an ongoing problem. Chromosomal translocations o...
Hexatetra-Carbon: A Novel Two-Dimensional Semiconductor Allotrope of Carbon [0.03%]
六联苯碳：一种新的二维半导体同素异形体Carbon allotrope
Mosayeb Naseri,Jaafar Jalilian,Dennis R Salahub et al.
Mosayeb Naseri et al.
Employing first-principles calculations based on density functional theory (DFT), we designed a novel two-dimensional (2D) elemental monolayer allotrope of carbon called hexatetra-carbon. In the hexatetra-carbon structure, each carbon atom ...
Scott Christley,Chase Cockrell,Gary An
Scott Christley
A large and growing body of research implicates aberrant immune response and compositional shifts of the intestinal microbiota in the pathogenesis of many intestinal disorders. The molecular and physical interaction between the host and the...
Computational View toward the Inhibition of SARS-CoV-2 Spike Glycoprotein and the 3CL Protease [0.03%]
计算视角下SARS-CoV-2刺突糖蛋白和3CL蛋白酶的抑制作用分析
Zhen Qiao,Hongtao Zhang,Hai-Feng Ji et al.
Zhen Qiao et al.
Since the outbreak of the 2019 novel coronavirus disease (COVID-19), the medical research community is vigorously seeking a treatment to control the infection and save the lives of severely infected patients. The main potential candidates f...
SBMLSimulator: A Java Tool for Model Simulation and Parameter Estimation in Systems Biology [0.03%]
基于系统生物学的模型模拟与参数估计的Java工具SBMLSimulator
Alexander Dörr,Roland Keller,Andreas Zell et al.
Alexander Dörr et al.
The identification of suitable model parameters for biochemical reactions has been recognized as a quite difficult endeavor. Parameter values from literature or experiments can often not directly be combined in complex reaction systems. Nat...
Simeone Marino,Caitlin Hult,Paul Wolberg et al.
Simeone Marino et al.
Within the first 2-3 months of a Mycobacterium tuberculosis (Mtb) infection, 2-4 mm spherical structures called granulomas develop in the lungs of the infected hosts. These are the hallmark of tuberculosis (TB) infection in humans and non-h...
An Overview of Network-Based and -Free Approaches for Stochastic Simulation of Biochemical Systems [0.03%]
基于网络和无网络方法对生化系统随机模拟的研究进展
Abhishekh Gupta,Pedro Mendes
Abhishekh Gupta
Stochastic simulation has been widely used to model the dynamics of biochemical reaction networks. Several algorithms have been proposed that are exact solutions of the chemical master equation, following the work of Gillespie. These stocha...
A Multi-Compartment Hybrid Computational Model Predicts Key Roles for Dendritic Cells in Tuberculosis Infection [0.03%]
一个多重隔间的计算模型预测树突细胞在结核病感染中发挥关键作用
Simeone Marino,Denise E Kirschner
Simeone Marino
Tuberculosis (TB) is a world-wide health problem with approximately 2 billion people infected with Mycobacterium tuberculosis (Mtb, the causative bacterium of TB). The pathologic hallmark of Mtb infection in humans and Non-Human Primates (N...