Strain Matching of Seasonal Influenza Vaccines and Emergence of Neuraminidase Inhibitor Resistance in China from 2015 to 2025 [0.03%]
2015至2025年我国流感疫苗株匹配度及神经氨酸酶抑制剂耐药性的出现
Peiqing He,Junhao Luo,Siyu Pu et al.
Peiqing He et al.
Background: Influenza remains a major global public health threat, and vaccination is one of the most effective preventive measures. However, frequent antigenic drift and occasional antigenic shift, along with the lead time required for vac...
Prevention of Infections in Early Life: Advances, Challenges and Future Directions [0.03%]
生命早期感染的预防：进展、挑战与未来方向
Eleni Vergadi
Eleni Vergadi
The early stages of life represent a critical window that shapes health and well-being throughout the lifespan [...].
Challenges, Advances, and Future Directions in Nipah Virus Vaccine Development [0.03%]
尼帕病毒疫苗研发的挑战、进展和未来方向
Hongshan Xu,Xuanxuan Zhang,Shuai Shang et al.
Hongshan Xu et al.
Nipah virus (NiV) is a highly pathogenic zoonotic pathogen. Since its discovery in 1998, recurrent epidemics have occurred in South and Southeast Asia, with a case fatality rate ranging from 40% to 100%. The outbreak in West Bengal, India i...
Rapid LC-MS Quantification of mRNA Vaccine Capping Efficiency via High-Specificity RNase H Cleavage and Metal Adduct Suppressed Chromatography [0.03%]
基于高特异性RNase H切割和金属配体抑制型色谱的信使核糖核酸疫苗5'端CAP结构定量分析方法学研究
Ren Yang,Xiaohong Wu,Xiaowei Zhang et al.
Ren Yang et al.
Background: The m7G cap structure, which mimics the natural cap of eukaryotic mRNA, is a critical determinant of mRNA vaccine efficacy, safety, and stability. However, its precise quantification remains challenging due to complex impurity p...
The Moderating Role of Demographic Variables in the Effect of Health Literacy on Anti-Vaccination Sentiment [0.03%]
人口统计学变量在健康素养影响反疫苗情绪中的调节作用
Ilkay Altunsoy,Berkay Kargili,Abdulhalim Senyigit
Ilkay Altunsoy
Background/objective: Vaccine hesitancy continues to pose a challenge to public health, and health literacy has been suggested as a potential factor influencing vaccination attitudes. However, the nature of this relations...
Immunization Status and Effectiveness Analysis of Hepatitis B Vaccine Among Preterm Infants in Fujian Province, 2022-2023 [0.03%]
福建省2022—2023年早产儿乙肝疫苗免疫状况及效果分析
Hairong Zhang,Jie Zhang,Zhikun Cai et al.
Hairong Zhang et al.
Objective: This study evaluated hepatitis B vaccine (HepB) uptake, associated influencing factors, and post-vaccination immune responses among preterm infants residing in Fujian Province. The findings can support targeted improvements in he...
Encephalitic Alphaviruses: Epidemiology, Pathogenesis and Vaccine Development [0.03%]
脑炎病毒的流行病学、发病机理及疫苗开发
Nouha Kisra,Zoe de Zeeuw,George Eustace et al.
Nouha Kisra et al.
Eastern, Venezuelan, and Western equine encephalitis viruses (EEEV, VEEV, and WEEV) are encephalitic alphaviruses transmitted by mosquitoes throughout the Americas. Infection by these viruses can present in humans as a febrile illness; howe...
The Potential of Intraepithelial Lymphocytes as Immunological Targets for the Induction of Innate and Adaptive Memory Responses Through Mucosal Vaccination and Prime Boost [0.03%]
黏膜免疫接种和初次与增强免疫应答诱导固有和适应性记忆反应的上皮内淋巴细胞的潜能
Gloria G Guerrero-Manríquez,Marco A De León-Nava
Gloria G Guerrero-Manríquez
The mucosal surfaces of the different tracts of the human body occupy a vast interface (around 400 m2), and defense at these sites represents the first line of immune defense. It is at the interface of these surfaces that a cellular and mol...
Advancing Global Hepatitis B Elimination: The Case for Using Maize as a Low-Cost, Heat-Stable, and Scalable Oral Vaccine [0.03%]
全球消除乙型肝炎有望：使用玉米作为低成本、耐热且可大规模生产的口服疫苗的前景分析
Muneaki Watanabe,John A Howard
Muneaki Watanabe
Because hepatitis B virus (HBV) remains a major global health burden, innovative strategies are essential to achieve the World Health Organization's goal of eliminating viral hepatitis and closing persistent coverage gaps for injectable vac...
Vaccine Hesitancy Among Caregivers in China: Associations of Misinterpreted AEFI, Compensation Awareness, and Institutional Trust [0.03%]
中国儿童监护人群体的疫苗犹豫现象：错误解读的AEFI、补偿意识和机构信任之间的关系
Binyue Xu,Qing Wang,Jiawei Xu et al.
Binyue Xu et al.
Background: Vaccine hesitancy remains a major global public health challenge despite high immunization coverage. While concerns about adverse events following immunization (AEFI) are widely recognized, limited attention h...