Pilot-Scale Downstream Processing of Recombinant Influenza Virus Vectors Expressing Brucella spp. Antigens Using an Integrated Membrane-Chromatography Purification Platform [0.03%]
基于集成膜层析纯化平台的重组流感病毒载体（表达布鲁氏菌抗原）公斤级下游工艺开发
Nurika Assanzhanova,Aigerim Sagymbayeva,Gaukhar Shynybekova et al.
Nurika Assanzhanova et al.
Background: Brucellosis remains a significant zoonotic infection affecting approximately 500,000 people worldwide annually, with no licensed human vaccine available. Recombinant influenza virus vectors expressing Brucella spp. antigens repr...
Development of a New Feline Combination Vaccine Including a Novel RNA Particle Vaccine Against Feline Leukemia Virus [0.03%]
一种新的猫联合疫苗的开发，包括一种针对猫白血病病毒的新RNA颗粒疫苗的发展
Willem Huisman,Aart Mommen,Stephanie Basten et al.
Willem Huisman et al.
Background/objectives: We describe the rationale, design and evaluation of a novel feline combination vaccine (Nobivac® NXT HCPChFeLV) incorporating RNA particle technology against feline leukemia virus (FeLV) alongside ...
Maternal Immunization Against Respiratory Syncytial Virus: An Integrative Review of Efficacy, Safety, and Implementation [0.03%]
呼吸道合胞病毒的孕妇免疫接种：疗效、安全性和实施策略的整合评价
Isadora Rodrigues Almeida,Marcela Fermoselle de Vita Silva,Taline de Brito Cavalcante et al.
Isadora Rodrigues Almeida et al.
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract infection in young infants and accounts for substantial morbidity, hospitalization, and mortality worldwide, with the highest burden concentrated in the ...
Hepatitis B Vaccination in People Living with HIV: Bridging the Immunological Gap [0.03%]
艾滋病病毒感染者乙肝疫苗接种：弥合免疫学差距
Christelle Radi,Jana Abu Faraj,Jad Idriss et al.
Christelle Radi et al.
Hepatitis B virus (HBV) infection remains a major driver of liver-related morbidity and mortality among people living with HIV (PLWH), yet vaccine-induced protection is frequently suboptimal. HIV-associated immune dysfunction, including CD4...
From Vaccine Skepticism to Institutional Distrust: The Post-Pandemic Shift [0.03%]
从疫苗怀疑论到制度不信任：疫情后的转变
Francesco De Maria,Francesco Branda,Giancarlo Ceccarelli et al.
Francesco De Maria et al.
Background: Vaccine hesitancy has traditionally been understood as a multifactorial phenomenon shaped by individual beliefs, risk perceptions, and access barriers. However, the COVID-19 pandemic has fundamentally transformed the relationshi...
Human Papillomavirus Vaccine Intent and Associated Factors Among the Unvaccinated University Freshmen in the Largest University Town in China [0.03%]
在中国最大的大学城镇中未接种疫苗的大学新生的人乳头瘤病毒疫苗接种意向及影响因素调查研究
Hongcen Yao,Hongmei Lu,Qi Zhu et al.
Hongcen Yao et al.
Background: Human papillomavirus (HPV) vaccine has been proven a safe, necessary, and effective measure against HPV infection. However, HPV vaccine uptake remains limited among university students in China. This study investigated HPV vacci...
M D Faizul Hussain Khan,Tahsina Islam,Abhishek Mishra et al.
M D Faizul Hussain Khan et al.
Messenger RNA-lipid nanoparticle (mRNA-LNP)-based drug products represent a promising platform for prophylactic and therapeutic applications. However, their limited stability poses significant challenges for storage and global distribution....
Generating Patient-Specific Anti-Tumor Responses with Non-Genetically Altered 'Off-the-Shelf' Allogeneic Cell Therapy: Leveraging Allo-Incompatibility for In Situ Vaccination [0.03%]
利用非遗传工程改造的异体细胞疗法生成患者特异性抗肿瘤反应：利用不合基因型进行原位接种疫苗
Michael Har-Noy
Michael Har-Noy
Generating personalized anti-tumor immune responses remains a primary objective of precision oncology, yet conventional autologous platforms face critical biological and logistical constraints. While current research modifies allogeneic lin...
Vaccination Coverage Among Preschool Children in Germany: Trends, Regional Disparities, and Determinants from School Enrolment Examinations in Two Metropolitan Regions [0.03%]
德国学龄前儿童的疫苗接种覆盖率：来自两个大都市地区入学体检的趋势、区域差异和决定因素
Christopher Michael Dyer,Judith Welker,Kholoud Assaad et al.
Christopher Michael Dyer et al.
Background: Vaccinations are highly effective in preventing infectious diseases, which otherwise present a serious challenge to the health of individuals and public health. To identify potential gaps in vaccination coverage, we examined chi...
Association Between Varicella Vaccination Status and Self-Reported Contact History Among Confirmed Varicella Cases in Chaoyang District, Beijing, 2017-2025 [0.03%]
2017—2025年北京市朝阳区水痘实验室确诊病例接种史与发病接触史关联分析
Yang Cao,Hao Wang,Ziwei Zhao et al.
Yang Cao et al.
Objectives: To investigate associations between varicella vaccination and self-reported contact history with varicella or herpes zoster among clinically diagnosed varicella cases in Chaoyang District, Beijing, China. Methods: A retrospectiv...