Ulrich Certa
Ulrich Certa
Microarrays covers research where microarrays are applied to address complex biological questions. This new open access journal publishes articles where novel applications or state-of-the art technology developments in the field are reporte...
A Transcriptome-Targeting EcoChip for Assessing Functional Mycodiversity [0.03%]
一种用于评估功能性真菌多样性的转录组靶向EcoChip
Derek Peršoh,Alfons R Weig,Gerhard Rambold
Derek Peršoh
A functional biodiversity microarray (EcoChip) prototype has been developed to facilitate the analysis of fungal communities in environmental samples with broad functional and phylogenetic coverage and to enable the incorporation of nucleic...
Microbial Diagnostic Microarrays for the Detection and Typing of Food- and Water-Borne (Bacterial) Pathogens [0.03%]
用于检测和分型食源性和水源性（细菌）病原体的微生物诊断芯片技术
Tanja Kostić,Angela Sessitsch
Tanja Kostić
Reliable and sensitive pathogen detection in clinical and environmental (including food and water) samples is of greatest importance for public health. Standard microbiological methods have several limitations and improved alternatives are ...
The Journal Microarrays [0.03%]
微阵列杂志
Shu-Kun Lin
Shu-Kun Lin
Our publishing company MDPI AG has its headquarters in Basel, Switzerland where there are thousands of scientists working in the laboratories of pharmaceutical companies and institutes including Novartis [1], F. Hoffmann-La Roche [2] and in...
Ruprecht Kuner
Ruprecht Kuner
Microarrays have been used for more than two decades in preclinical research. The tumor transcriptional profiles were analyzed to select cancer-associated genes for in-deep functional characterization, to stratify tumor subgroups according ...
Chromosomal Microarrays in Prenatal Diagnosis: Time for a Change of Policy? [0.03%]
产前诊断染色体微阵列检查：改变政策的时候到了吗？
Peter Miny,Friedel Wenzel,Sevgi Tercanli et al.
Peter Miny et al.
Microarrays have replaced conventional karyotyping as a first-tier test for unbalanced chromosome anomalies in postnatal cytogenetics mainly due to their unprecedented resolution facilitating the detection of submicroscopic copy number chan...
Philip Ginsbach,Bowang Chen,Yanxiang Jiang et al.
Philip Ginsbach et al.
System noise was analyzed in 77 Affymetrix 6.0 samples from a previous clinical study of copy number variation (CNV). Twenty-three samples were classified as eligible for CNV detection, 29 samples as ineligible and 25 were classified as bei...
Kernel-Based Aggregation of Marker-Level Genetic Association Tests Involving Copy-Number Variation [0.03%]
基于内核的拷贝数变异涉及的标记水平遗传关联测试的聚合方法
Yinglei Li,Patrick Breheny
Yinglei Li
Genetic association tests involving copy-number variants (CNVs) are complicated by the fact that CNVs span multiple markers at which measurements are taken. The power of an association test at a single marker is typically low, and it is des...
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prognosis [0.03%]
从高通量微阵列筛选到临床应用——乳腺癌预后第二代多基因检测的开发
Jan C Brase,Ralf Kronenwett,Christoph Petry et al.
Jan C Brase et al.
Several multigene tests have been developed for breast cancer patients to predict the individual risk of recurrence. Most of the first generation tests rely on proliferation-associated genes and are commonly carried out in central reference...
Improving Pathological Assessment of Breast Cancer by Employing Array-Based Transcriptome Analysis [0.03%]
利用基于阵列的转录组分析改善乳腺癌病理评估
Zsuzsanna Mihály,Balázs Győrffy
Zsuzsanna Mihály
Breast cancer research has paved the way of personalized oncology with the introduction of hormonal therapy and the measurement of estrogen receptor as the first widely accepted clinical biomarker. The expression of another receptor-HER2/ER...