Modeling Hybridization Kinetics of Gene Probes in a DNA Biochip Using FEMLAB [0.03%]
采用FEMLAB模拟DNA芯片中基因探针的杂交动力学模型研究
Ahsan Munir,Hassan Waseem,Maggie R Williams et al.
Ahsan Munir et al.
Microfluidic DNA biochips capable of detecting specific DNA sequences are useful in medical diagnostics, drug discovery, food safety monitoring and agriculture. They are used as miniaturized platforms for analysis of nucleic acids-based bio...
Microarray Selection of Cooperative Peptides for Modulating Enzyme Activities [0.03%]
用于调节酶活性的协同肽的微阵列筛选
Jinglin Fu
Jinglin Fu
Recently, peptide microarrays have been used to distinguish proteins, antibodies, viruses, and bacteria based on their binding to random sequence peptides. We reported on the use of peptide arrays to identify enzyme modulators that involve ...
Mary Shannon Byers,Christianna Howard,Xiaofei Wang
Mary Shannon Byers
The GLUT members belong to a family of glucose transporter proteins that facilitate glucose transport across the cell membrane. The mammalian GLUT family consists of thirteen members (GLUTs 1-12 and H⁺-myo-inositol transporter (HMIT)). Hum...
Use of a Pan-Genomic DNA Microarray in Determination of the Phylogenetic Relatedness among Cronobacter spp. and Its Use as a Data Mining Tool to Understand Cronobacter Biology [0.03%]
全基因组DNA微阵列在肠杆菌属物种间系统发育亲缘关系测定中的应用及其作为工具用于研究肠杆菌生物学的用途
Ben D Tall,Jayanthi Gangiredla,Christopher J Grim et al.
Ben D Tall et al.
Cronobacter (previously known as Enterobacter sakazakii) is a genus of Gram-negative, facultatively anaerobic, oxidase-negative, catalase-positive, rod-shaped bacteria of the family Enterobacteriaceae. These organisms cause a variety of ill...
Diana Mabel Kelmansky,Lila Ricci
Diana Mabel Kelmansky
The traditional approach with microarray data has been to apply transformations that approximately normalize them, with the drawback of losing the original scale. The alternative stand point taken here is to search for models that fit the dat...
DNA Microarray-Based Screening and Characterization of Traditional Chinese Medicine [0.03%]
基于DNA微阵列的技术筛选及分析传统中药
Ryoiti Kiyama
Ryoiti Kiyama
The application of DNA microarray assay (DMA) has entered a new era owing to recent innovations in omics technologies. This review summarizes recent applications of DMA-based gene expression profiling by focusing on the screening and charac...
Robert G Hamilton
Robert G Hamilton
IgE antibodies serve as the gatekeeper for the release of mediators from sensitized (IgE positive) mast cells and basophils following a relevant allergen exposure which can lead to an immediate-type hypersensitivity (allergic) reaction. Pur...
Application of Lectin Array Technology for Biobetter Characterization: Its Correlation with FcγRIII Binding and ADCC [0.03%]
应用凝集素芯片技术进行生物类似药表征及其与FcγRIII结合和ADCC的相关性研究
Markus Roucka,Klaus Zimmermann,Markus Fido et al.
Markus Roucka et al.
Lectin microarray technology was applied to compare the glycosylation pattern of the monoclonal antibody MB311 expressed in SP2.0 cells to an antibody-dependent cellular cytotoxic effector function (ADCC)-optimized variant (MB314). MB314 wa...
Pietro Hiram Guzzi,Giuseppe Tradigo,Pierangelo Veltri
Pietro Hiram Guzzi
MicroRNAs (miRNAs) are small biological molecules that play an important role during the mechanisms of protein formation. Recent findings have demonstrated that they act as both positive and negative regulators of protein formation. Thus, t...
Droplet Microarray Based on Superhydrophobic-Superhydrophilic Patterns for Single Cell Analysis [0.03%]
基于超疏水/超亲水图案的液滴微阵列单细胞分析技术
Gabriella E Jogia,Tina Tronser,Anna A Popova et al.
Gabriella E Jogia et al.
Single-cell analysis provides fundamental information on individual cell response to different environmental cues and is a growing interest in cancer and stem cell research. However, current existing methods are still facing challenges in p...