Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders [0.03%]
定量化性状位点和大脑中的HLA-DPA1表达为精神疾病中免疫改变提供证据
Ling Z Morgan,Brandi Rollins,Adolfo Sequeira et al.
Ling Z Morgan et al.
Genome-wide association studies of schizophrenia encompassing the major histocompatibility locus (MHC) were highly significant following genome-wide correction. This broad region implicates many genes including the MHC complex class II. Wit...
Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders [0.03%]
定量化性状基因座和脑部HLA-DPA1表达为精神疾病中共同的免疫改变提供了证据
Ling Z Morgan,Brandi Rollins,Adolfo Sequeira et al.
Ling Z Morgan et al.
Genome-wide association studies of schizophrenia encompassing the major histocompatibility locus (MHC) were highly significant following genome-wide correction. This broad region implicates many genes including the MHC complex class II. Wit...
Screening of Small Molecule Microarrays for Ligands Targeted to the Extracellular Epitopes of Living Cells [0.03%]
活细胞小分子微阵列筛选及靶向胞外表位的配体鉴定
Jeong Heon Lee,Kai Bao,John V Frangioni et al.
Jeong Heon Lee et al.
The screening of living cells using high-throughput microarrays is technically challenging. Great care must be taken in the chemical presentation of potential ligands and the number of collisions that cells make with them. To overcome these...
An Optimization-Driven Analysis Pipeline to Uncover Biomarkers and Signaling Paths: Cervix Cancer [0.03%]
一种用于发现生物标志物和信号通路的优化分析方法：宫颈癌研究
Enery Lorenzo,Katia Camacho-Caceres,Alexander J Ropelewski et al.
Enery Lorenzo et al.
Establishing how a series of potentially important genes might relate to each other is relevant to understand the origin and evolution of illnesses, such as cancer. High-throughput biological experiments have played a critical role in provi...
The Transcriptomics to Proteomics of Hair Cell Regeneration: Looking for a Hair Cell in a Haystack [0.03%]
从转录组学到蛋白质组学：在乱堆中寻发细胞
Michael E Smith,Gopinath Rajadinakaran
Michael E Smith
Mature mammals exhibit very limited capacity for regeneration of auditory hair cells, while all non-mammalian vertebrates examined can regenerate them. In an effort to find therapeutic targets for deafness and balance disorders, scientists ...
Bin Wang,Yaguang Xi
Bin Wang
Microarray is a high throughput discovery tool that has been broadly used for genomic research. Probe-target hybridization is the central concept of this technology to determine the relative abundance of nucleic acid sequences through fluor...