A Combinatorial Protein Microarray for Probing Materials Interaction with Pancreatic Islet Cell Populations [0.03%]
一种用于检测胰岛细胞群体与材料相互作用的组合蛋白质微阵列技术
Bahman Delalat,Darling M Rojas-Canales,Soraya Rasi Ghaemi et al.
Bahman Delalat et al.
Pancreatic islet transplantation has become a recognized therapy for insulin-dependent diabetes mellitus. During isolation from pancreatic tissue, the islet microenvironment is disrupted. The extracellular matrix (ECM) within this space not...
Serology in the Digital Age: Using Long Synthetic Peptides Created from Nucleic Acid Sequences as Antigens in Microarrays [0.03%]
数字化时代下的血清学研究：利用长合成肽作为微阵列中的抗原进行实验，这些合成肽由核苷酸序列编码而来
Muhammad Rizwan,Bengt Rönnberg,Maksims Cistjakovs et al.
Muhammad Rizwan et al.
Background: Antibodies to microbes, or to autoantigens, are important markers of disease. Antibody detection (serology) can reveal both past and recent infections. There is a great need for development of rational ways of...
The Potentials and Pitfalls of Microarrays in Neglected Tropical Diseases: A Focus on Human Filarial Infections [0.03%]
微阵列在被忽视的热带病中的潜在应用和面临的挑战——以人类丝虫感染为例
Alexander Kwarteng,Samuel Terkper Ahuno
Alexander Kwarteng
Data obtained from expression microarrays enables deeper understanding of the molecular signatures of infectious diseases. It provides rapid and accurate information on how infections affect the clustering of gene expression profiles, pathw...
Protein Profiling Gastric Cancer and Neighboring Control Tissues Using High-Content Antibody Microarrays [0.03%]
基于高内涵抗体微阵列的胃癌及邻近正常组织蛋白质谱分析
Martin Sill,Christoph Schröder,Ying Shen et al.
Martin Sill et al.
In this study, protein profiling was performed on gastric cancer tissue samples in order to identify proteins that could be utilized for an effective diagnosis of this highly heterogeneous disease and as targets for therapeutic approaches. ...
MicroRNA Profile of Lung Tumor Tissues Is Associated with a High Risk Plasma miRNA Signature [0.03%]
肺肿瘤组织的微小核糖核酸谱型与高风险血浆微小核糖核酸标志物有关联
Orazio Fortunato,Carla Verri,Ugo Pastorino et al.
Orazio Fortunato et al.
Lung cancer is the most common cause of cancer deaths worldwide. MicroRNAs (miRNAs) are short, non-coding RNAs that regulate gene expression. Many studies have reported that alterations in miRNA expression are involved in several human tumo...
SNPConvert: SNP Array Standardization and Integration in Livestock Species [0.03%]
SNPConvert：家畜品种的SNP阵列标准化与整合
Ezequiel Luis Nicolazzi,Gabriele Marras,Alessandra Stella
Ezequiel Luis Nicolazzi
One of the main advantages of single nucleotide polymorphism (SNP) array technology is providing genotype calls for a specific number of SNP markers at a relatively low cost. Since its first application in animal genetics, the number of ava...
Evaluation of Solid Supports for Slide- and Well-Based Recombinant Antibody Microarrays [0.03%]
用于滑动和井式重组抗体微阵列的固体支撑物的评估
Anna S Gerdtsson,Linda Dexlin-Mellby,Payam Delfani et al.
Anna S Gerdtsson et al.
Antibody microarrays have emerged as an important tool within proteomics, enabling multiplexed protein expression profiling in both health and disease. The design and performance of antibody microarrays and how they are processed are depend...
Enhancing Interpretability of Gene Signatures with Prior Biological Knowledge [0.03%]
利用先验生物学知识增强基因特征的可解释性
Margherita Squillario,Matteo Barbieri,Alessandro Verri et al.
Margherita Squillario et al.
Biological interpretability is a key requirement for the output of microarray data analysis pipelines. The most used pipeline first identifies a gene signature from the acquired measurements and then uses gene enrichment analysis as a tool ...
Retrospective Proteomic Analysis of Cellular Immune Responses and Protective Correlates of p24 Vaccination in an HIV Elite Controller Using Antibody Arrays [0.03%]
精英控制者中p24疫苗接种的细胞免疫反应和保护相关因素的抗体阵列蛋白组学分析回顾性研究
Suneth S Perera,Bin Wang,Arturo Damian et al.
Suneth S Perera et al.
HIV p24 is an extracellular HIV antigen involved in viral replication. Falling p24 antibody responses are associated with clinical disease progression and their preservation with non-progressive disease. Stimulation of p24 antibody producti...
Advantages of Array-Based Technologies for Pre-Emptive Pharmacogenomics Testing [0.03%]
阵列技术在预测型药物基因分型检测中的优势
Al Shahandeh,Daniel M Johnstone,Joshua R Atkins et al.
Al Shahandeh et al.
As recognised by the National Institutes of Health (NIH) Precision Medicine Initiative (PMI), microarray technology currently provides a rapid, inexpensive means of identifying large numbers of known genomic variants or gene transcripts in ...