Axonal Transport Deficits in Parkinson's Disease: Insights from Neurotoxin, Genetic, and Sporadic Models [0.03%]
帕金森病的轴突运输缺陷:来自神经毒素、基因和散发模型的见解
Xiaobo Wang,Zhaohui Liu,Wanli W Smith
Xiaobo Wang
Parkinson's disease (PD) is a prevalent neurodegenerative disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of Lewy bodies. Over recent decades, various cellular mechanism...
Spasticity in Prolonged Disorders of Consciousness: A Prospective Cohort Study [0.03%]
意识障碍的僵直:前瞻性队列研究
Nathalie Draulans,Cecile Utens,Danielle Driessen et al.
Nathalie Draulans et al.
Background: Spasticity is a frequent and disabling complication in patients with prolonged disorders of consciousness (PDOC), yet its prevalence, distribution, evolution, and relationship with recovery of consciousness remain poorly charact...
Human-Derived Cellular Models in Psychiatry: A Focus on the Olfactory Neuroepithelium [0.03%]
精神病学中的人源细胞模型:关注嗅觉上皮组织
Tommaso Toffanin,Mario Angelo Pagano,Carlo Idotta et al.
Tommaso Toffanin et al.
Severe mental disorders, including schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD), are leading causes of global disability, yet current treatments remain largely symptomatic and fail to alter disease traject...
When the Clock Shifts: A Comprehensive Review of Daylight-Saving Time (DST), Circadian Disruption, and Neuropsychological Risk in Chronic Mental Illness [0.03%]
当钟表变动时:夏令时、昼夜节律紊乱和慢性精神疾病患者神经心理风险的全面综述
Liahm Blank,Joshua Khorsandi,Elizabeth England-Kennedy et al.
Liahm Blank et al.
Daylight Saving Time (DST) creates abrupt, externally imposed circadian disruptions that can impair sleep regulation, hormonal balance, cognitive performance, and emotional stability. Although these effects are known in the general populati...
Genomic Profiling of Adults with Pharmacoresistant Genetic Generalized Epilepsy [0.03%]
成人药物抵抗性遗传性全身性癫痫的基因组谱分析
Benjamin L Kidder,Jian Xu,Rui Geng et al.
Benjamin L Kidder et al.
Background/Objectives: Genetic generalized epilepsies (GGE) often remit in childhood, yet a subset of adults remain pharmacoresistant with substantial morbidity. The genetic basis of adult pharmacoresistant GGE is poorly defined. This descr...
Modifiable Barriers to Assessment and Rehabilitation in Justice-Involved Individuals with Self-Reported TBI: The Role of Subjective Sleepiness and Mood [0.03%]
司法涉入个体中自述性TBI评估和康复的可变障碍:主观嗜睡和情绪的作用
Sarka Turecka Brown,Maddy Pontius,Jennifer Gallagher et al.
Sarka Turecka Brown et al.
Background/Objectives: Sleep problems, cognitive deficits, and mood disorders are prevalent in justice-involved populations, especially among individuals with a history of traumatic brain injury (TBI), though the association between these v...
Mapping the Human Performance Envelope Through Multivariate Information Transfer [0.03%]
基于多元信息传递的人类性能范围研究
Gianluca Borghini,Khadija Latrach,Gianluca Di Flumeri et al.
Gianluca Borghini et al.
Background/objectives: The human performance envelope (HPE) is a multidimensional model that represents the range in which an individual operator's performance is acceptable or begins to become dangerous. Although several...
Multivariate Associations Between R-PAS Variables and Suicidal Ideation and Behaviors in Help-Seeking Adolescents [0.03%]
R-PAS变量与寻求帮助的青少年自杀意念和行为之间的多元关联性分析
Marzia Di Girolamo,Roberta Invernizzi,Paola Galli et al.
Marzia Di Girolamo et al.
Background/Objectives: Suicidal ideation and behavior in adolescence remain difficult to assess due to their multifactorial and fluctuating nature. Performance-based measures may provide additional information on psychological correlates as...
Is There Still a Role for Twist Drill Craniostomy in Contemporary Management of Chronic Subdural Hematoma? [0.03%]
当前慢性硬膜下血肿治疗中扭钻颅骨切开术仍有作用吗?
Hussam Hamou,Hani Ridwan,Anna Mausberg et al.
Hussam Hamou et al.
Background/Objectives: Chronic subdural hematoma (cSDH) is an increasingly prevalent neurosurgical condition in the aging population. Burr hole craniotomy (BHC) with irrigation and postoperative drainage represents the evidence-based standa...
Ecological Momentary Assessment of Fatigue in Adults with Cerebral Palsy: Feasibility, Reliability, and Validity [0.03%]
脑瘫成人疲乏体验的生态瞬时评估法:可行性、信度和效度研究
Frederik Have Dornonville de la Cour,Sun-Hee Skovgaard Christensen,Stine Flensburg Hansen et al.
Frederik Have Dornonville de la Cour et al.
Background/Objectives: Fatigue is a common symptom in adults with cerebral palsy (CP), characterized by fluctuations across the day. This pilot study aimed to evaluate the feasibility, reliability, and validity of ecological momentary asses...