Opicapone as Add-On Therapy to Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion: Clinical Improvement and Wearable Sensor-Based Gait Analysis [0.03%]
作为连续皮下注射左旋多巴/卡比多巴附加疗法的奥匹哌烷:临床改善和可穿戴传感器步态分析
Paolo Solla,Carla Masala,Gianluca Martinez et al.
Paolo Solla et al.
Background/objectives: Continuous subcutaneous foslevodopa/foscarbidopa infusion (CSFLI) improves motor fluctuations in advanced Parkinson's disease (PD), but some patients continue to experience residual motor and non-mo...
Case Reports
Brain sciences. 2026 May 21;16(5):545. DOI:10.3390/brainsci16050545 2026
Amelia Rizzo,Maria Grazia Maggio,Martina Barbera et al.
Amelia Rizzo et al.
Background: Workplace victimization is a form of repeated and systematic psychological violence that can severely affect both mental and physical health. From a psychological perspective, it impacts mood states, defense mechanisms, and pers...
New Advances in the Development of New Drugs and Treatment Targets for Brain Cancers (2nd Edition) [0.03%]
新药和脑肿瘤治疗靶点研发进展(第二版)
Luis Exequiel Ibarra,Laura Natalia Milla Sanabria,Nuria Arias-Ramos
Luis Exequiel Ibarra
Primary tumors of the central nervous system (CNS) represent a major clinical challenge worldwide due to their high morbidity, aggressive biological behavior, and limited therapeutic options [...].
Modulation of the PI3K/AKT/mTOR and AMPK/TSC2/mTOR Pathways by N-Acetyl-L-Cysteine as a Protector of Embryonic Bodies from the Toxic Effect of Methylmercury [0.03%]
N-乙酰半胱氨酸通过PI3K / AKT / mTOR和AMPK / TSC2 / mTOR途径对甲基汞胚胎毒性的保护作用
Júlia Leão Batista Simões,Geórgia de Carvalho Braga,Charles Elias Assmann et al.
Júlia Leão Batista Simões et al.
Methylmercury (MeHg) is a potent environmental contaminant primarily ingested through seafood consumption. Gestational exposure induces profound neurological and developmental deficits in the fetus that often persist throughout childhood. T...
Paper to Pixels: Enhancing Unilateral Neglect Assessment Using the New Computer Vision-Based Tool CANDO [0.03%]
从纸笔测试到计算机视觉:利用新型计算机视觉工具CANDO改善一侧面忽视综合症的评估
Lisa Beckmann,Rylan Donohoe,Doris Schmid et al.
Lisa Beckmann et al.
Background/Objectives: The main aim of this article is to introduce a novel tool that allows the automatic scoring of many of the subtests from the conventional subpart of the Behavioural Inattention Test (BIT) and its German adaptation, th...
Neural and Kinematic Characteristics of Reaching in Autistic Children During Movement Observation, Execution, and Synchronization: An fNIRS Study [0.03%]
自闭症儿童在运动观察、执行和同步过程中的神经和运动学特征:近红外光谱成像研究
Wan-Chun Su,Daisuke Tsuzuki,Anjana Bhat
Wan-Chun Su
Background/objectives: Children with Autism Spectrum Disorder (ASD, here on termed autistic children) exhibit motor difficulties in social and non-social contexts. Although previous studies have reported behavioral and ne...
Sympathetic Activation and Sleep-Related Movements: Integrating Autonomic, Dopaminergic, and Iron Deficiency Mechanisms [0.03%]
交感神经激活和睡眠相关运动:自主神经、多巴胺能及铁缺乏机制的整合
Gulcin Benbir Senel,Lourdes M DelRosso
Gulcin Benbir Senel
Objective: Recent research has expanded the understanding of the potential role of sympathetic nervous system activation in the implications of sleep-related movement disorders, particularly in the mechanisms of dopaminer...
Surgical Management of Traumatic Brain Injury Based on Intracranial Compliance: Toward Personalized Decision-Making [0.03%]
基于颅内顺应性的创伤性脑损伤外科治疗:迈向个性化决策
Santiago Cardona-Collazos,Laura M Loaiza-Cardona,Andres Salazar-Restrepo et al.
Santiago Cardona-Collazos et al.
Traditional surgical decision-making in traumatic brain injury (TBI) has relied on static intracranial pressure (ICP) thresholds and fixed volumetric criteria, an approach that inadequately reflects the dynamic physiological nature of secon...
Investigating Treatment Response in Obsessive-Compulsive Disorder Through Neuromodulation and Patient-Derived Induced Pluripotent Stem Cell Models: Preliminary Clinical Observations from a Translational Study [0.03%]
通过神经调控和患者来源的诱导多能干细胞模型研究强迫症的治疗反应:一项转化研究的初步临床观察
Beatrice Benatti,Matteo Marcatili,Rodolfo Leuzzi et al.
Beatrice Benatti et al.
Background: Treatment-resistant obsessive-compulsive disorder (OCD) is a heterogeneous and clinically challenging condition. Growing evidence suggests alterations in glutamatergic signaling within cortico-striatal-thalamo...
Sleep Quality Profiles in Youth with Eating Disorders: A Latent Profile Analysis [0.03%]
儿童饮食障碍的睡眠质量类型分析研究
Elvira Anna Carbone,Matteo Aloi,Renato de Filippis et al.
Elvira Anna Carbone et al.
Background/objectives: Sleep disturbances are highly prevalent in young individuals with eating disorders (EDs) and are associated with increased psychopathology and poorer clinical outcomes. However, sleep alterations in...