CircRNAs-Potential Diagnostic Biomarkers and Therapeutic Targets for Receptive and Cancerous Endometrium [0.03%]
Circular RNA分子作为诊断标志物和治疗靶点在子宫内膜异位症及癌变中的作用
Antoan Milov,Maria Nikolova,Stoilka Mandadzhieva et al.
Antoan Milov et al.
Circular RNAs (circRNAs) are small, non-coding RNAs in which the 5' and 3' ends are linked covalently by back-splicing of exons from a single pre-mRNA. More and more scientific evidence is gathered for their wide distribution in the animal ...
Epigenetic Regulation of Salt Stress Responses in Rice: Mechanisms and Prospects for Enhancing Tolerance [0.03%]
水稻耐盐应答的表观遗传调控机制及育种应用前景展望
Emanuela Talarico,Eleonora Greco,Francesco Guarasci et al.
Emanuela Talarico et al.
Rice (Oryza sativa L.) is a staple food for over half the global population and a model organism for monocot plant research. However, it is susceptible to salinity, with most cultivated varieties showing reduced growth at salt levels above ...
Sebastian Gaston Alvarado,Annaliese Chang,Maral Tajerian
Sebastian Gaston Alvarado
Background: Trait convergence or parallelism is widely seen across the animal and plant kingdoms. For example, the evolution of eyes in cephalopods and vertebrate lineages, wings in bats and insects, or shark and dolphin ...
Exploring the Impact of Nanotherapeutics on Histone H3 and H4 Acetylation Enrichment in Cancer Epigenome: A Systematic Scoping Synthesis [0.03%]
纳米药物对癌症表观基因组组蛋白H3和H4乙酰化富集的影响：系统性综述合成研究
Milad Shirvaliloo,Sepideh Khoee,Samideh Khoei et al.
Milad Shirvaliloo et al.
Background/Objectives: Histone acetylation regulates gene expression and plays a key role in cancer pathophysiology. Nanotherapeutics are known to modulate histone acetylation and influence cancer progression. This systematic scoping review...
Epigenetic Mechanisms of Plant Adaptation to Cadmium and Heavy Metal Stress [0.03%]
植物适应镉和重金属胁迫的表观遗传机制
Eleonora Greco,Emanuela Talarico,Francesco Guarasci et al.
Eleonora Greco et al.
Heavy metal and metalloid stress, particularly from toxic elements like cadmium (Cd), poses a growing threat to plant ecosystems, crop productivity, and global food security. Elevated concentrations of these contaminants can trigger cytotox...
Rakesh Srivastava,Niraj Lodhi
Rakesh Srivastava
N6-methyladenosine (m6A) is the most abundant and dynamic RNA modification in eukaryotic messenger and non-coding RNAs, playing a pivotal role in the post-transcriptional regulation of gene expression. The coordinated actions of m6A writers...
Exploration into the MLL4/WRAD Enzyme-Substrate Network: Systematic In Vitro Identification of CFP1 as a Potential Non-Histone Substrate of the MLL4 Lysine Methyltransferase [0.03%]
探索MLL4/WRAD酶底物网络：CFP1是MLL4组蛋白甲基转移酶潜在非组蛋白底物的系统体外鉴定
Mullen Boulter,Ryan Collins,Kyle K Biggar
Mullen Boulter
Lysine methylation is a critical post-translational modification catalyzed by lysine methyltransferases (KMTs), originally characterized in the regulation of histones. However, the breadth of non-histone targets remains largely unexplored. ...
Elevated Alcohol Consumption and Chronic Inflammation Predict Cardiovascular Risk Among Black Americans: Examination of a Dual-Risk Model Using Epigenetic Risk Markers [0.03%]
饮酒量增加和慢性炎症可预测美国黑人中的心血管风险：使用表观遗传学风险标志物检验双重风险模型
Steven R H Beach,Robert A Philibert,Mei-Ling Ong et al.
Steven R H Beach et al.
Background: Heart disease may take a greater toll on Black Americans than White Americans despite similar levels of traditional risk factors. Elevated alcohol consumption (EAC) and chronic inflammation are two potentially...
A Pilot Epigenome-Wide Study of Posttraumatic Growth: Identifying Novel Candidates for Future Research [0.03%]
一项创伤后成长表观基因组范围研究的试点研究：为未来的研究确定新的候选对象
Mackenzie Rubens,Paul Ruiz Pinto,Anita Sathyanarayanan et al.
Mackenzie Rubens et al.
Background: Posttraumatic growth (PTG) refers to positive psychological change following trauma. While its psychological aspects are well-documented, the biological mechanisms remain unclear. Epigenetic changes, such as D...
Tripartite Interaction of Epigenetic Regulation, Brain Aging, and Neuroinflammation: Mechanistic Insights and Therapeutic Implications [0.03%]
表观遗传调控、脑衰老与神经炎症的三重互作：机制阐释和治疗启示
Shenghui Mi,Hideyuki Nakashima,Kinichi Nakashima
Shenghui Mi
Aging of the central nervous system (CNS) involves widespread transcriptional and structural remodeling, prominently marked by synaptic loss, impaired neurogenesis, and glial dysfunction. While age-related gene expression changes have been ...