Nisha Ganesh,William M Grady,Andrew M Kaz
Nisha Ganesh
Colitis-associated colorectal cancer (CAC) represents a distinct subtype of colorectal malignancy that arises in the setting of chronic inflammatory bowel disease (IBD). Unlike sporadic colorectal cancer, CAC develops through inflammation-d...
Fisetin Suppresses the Proliferative and Migratory Behavior of HeLa Cells by Modulating Aberrant Epigenetic Marks (Writers and Erasers) [0.03%]
山柰酚通过调节异常表观遗传标记（书写者和擦除者）抑制HeLa细胞的增殖和迁移行为
Nazia Afroze,Reham I Alagal,Lujain A Almousa et al.
Nazia Afroze et al.
Purpose: The reversible deviant in epigenomic modulations is the highlight of developing new anti-cancer drugs, necessitating the use of fisetin as an epigenetic modifier in the study. ...
Epigenetic Regulation and Gene Expression Profiles in Cervical Swabs: Toward Non-Invasive Biomarkers of Cervical Lesion Progression [0.03%]
宫颈抹片的表观遗传调控及基因表达谱：非侵入性生物标志物筛查宫颈病变进展的研究
Ivana Kašubová,Andrea Hornáková,Lucia Kotúľová et al.
Ivana Kašubová et al.
Background/Objectives: Cervical cancer is a common malignancy in women worldwide, closely associated with persistent human papillomavirus (HPV) infection. Epigenetic mechanisms, particularly promoter methylation, may contribute to tumour pr...
Upregulation of a MicroRNA Signature Involving miR-17-5p, miR-26b-5p, miR-106a-5p, and miR-146a-5p During Cervical Epithelial Transformation [0.03%]
宫颈上皮细胞异常分化过程中miR-17-5p、miR-26b-5p、miR-106a-5p和miR-146a-5p表达水平上调
Andrea Hornakova,Zuzana Kolkova,Lucia Kotulova et al.
Andrea Hornakova et al.
Background: Cervical cancer remains the fourth most common malignancy among women worldwide. Despite vaccination and regular screening, new molecular biomarkers are needed for improved early detection and risk assessment. MicroRNAs (miRNAs)...
Epigenome-Wide Search for Distinctive Methylation Biomarkers of Endothelial and Leukocyte DNA [0.03%]
泛素端粒酶基因组范围Distinctive甲基化生物标志物的筛选研究：内皮细胞和白细胞DNA中的差异分析研究
Valeria A Korolenya,Maxim L Filipenko,Mariya A Smetanina
Valeria A Korolenya
The endothelium, as the inner layer of the vascular wall, is in constant contact with blood components, so that leukocytes have the ability to adhere to endotheliocytes and penetrate to the subendothelial space. When studying heterogenic va...
The Exosome-Mediated Epigenome: Non-Coding RNA and mRNA-Coding Networks in Microbiome-Cellular Communication, Inflammation, and Tumorigenesis Along the Oral-Gut-Lung Axis [0.03%]
沿口腔-肠道-肺轴的微生物群-细胞通讯、炎症和肿瘤发生的外泌体介导的表观基因组：非编码RNA和mRNA编码网络
Beatriz Andrea Otálora-Otálora,César Payán-Gómez,Juan Javier López-Rivera et al.
Beatriz Andrea Otálora-Otálora et al.
Background/Objectives: The oral-gut-lung axis represents a dynamic system where exosomes carrying mRNAs and non-coding RNAs might help to regulate microbiota and human cell crosstalk to establish transcriptional regulatory networks controll...
The Evolutionary Misfit: Evolution, Epigenetics, and the Rise of Non-Communicable Diseases [0.03%]
进化中的不合作者：进化、表观遗传学与非传染性疾病的兴起
Stefano Amatori
Stefano Amatori
Human life expectancy has risen dramatically in the last century, but this demographic triumph has come at the cost of an explosion of non-communicable diseases (NCDs), threatening the sustainability of healthcare systems in aging, low-fert...
The Epigenomic Impact of Quantum Dots: Emerging Biosensors and Potential Disruptors [0.03%]
量子点的表观基因组影响：新兴生物传感器和潜在干扰因素
Abhishu Chand,Kyoungtae Kim
Abhishu Chand
Quantum dots (QDs) have emerged as powerful tools in biomedical applications due to their unique optical and fluorescent properties which enable highly sensitive and multiplexed detection of biomolecules. Particularly in the field of epigen...
Introducing the EpG2 System: Epigenomic Processes and the Emergent Genome [0.03%]
Epg2系统问世——表观基因组进程与新兴基因组学说
Edward A Ruiz-Narváez
Edward A Ruiz-Narváez
Background/Objectives: Current genomics research equates the genome with DNA sequence and treats the epigenome as a regulatory layer. This DNA-centric view obscures the fact that genomic identity arises through epigenomic processes. The obj...
Adverse Childhood Experiences, DNA Methylation, and Depressive Symptoms in Black Pregnant Women [0.03%]
童年不良经历、DNA甲基化和黑人孕妇的抑郁症状
Alexandra L Nowak,Marvin A Schilt-Solberg,Xiaoyu Liang et al.
Alexandra L Nowak et al.
Background: Prenatal depression, affecting up to a quarter of all pregnancies in the United States, contributes to morbidity and mortality and is associated with increased risk of adverse birth and long-term mental health...