The Complete Mitochondrial Genome of Stromateus stellatus (Scombriformes: Stromateidae): Organization, Gene Arrangement, and Phylogenetic Position Within the Suborder Stromateoidei [0.03%]
刺鳞鱼（金枪鱼形目：刺鳞鱼科）线粒体基因组的组织、基因排列及在刺鳞鱼亚目的系统发育地位
Fernanda E Angulo,Rodrigo Pedrero-Pacheco,José J Nuñez
Fernanda E Angulo
Background/objectives: The butterfish Stromateus stellatus is undervalued and usually discarded as bycatch, leading to an inefficient and unsustainable use of marine biomass. Overall, although Stromateus is the type genus...
Attention-Guided Probabilistic Diffusion Model for Generating Cell-Type-Specific Gene Regulatory Networks from Gene Expression Profiles [0.03%]
基于注意力引导的概率扩散模型：从基因表达谱生成细胞类型特异性基因调控网络
Shiyu Xu,Na Yu,Daoliang Zhang et al.
Shiyu Xu et al.
Gene regulatory networks (GRN) govern cellular identity and function through precise control of gene transcription. Single-cell technologies have provided powerful means to dissect regulatory mechanisms within specific cellular states. Howe...
Bioinformatics Approach to mTOR Signaling Pathway-Associated Genes and Cancer Etiopathogenesis [0.03%]
利用生物信息学方法研究mTOR信号通路相关基因与癌症发病机制的关系
Kursat Ozdilli,Gozde Oztan,Demet Kıvanç et al.
Kursat Ozdilli et al.
Background/Objectives: The mTOR serine/threonine kinase coordinates protein translation, cell growth, and metabolism, and its dysregulation promotes tumorigenesis. We present a reproducible, pan-cancer, network-aware framework that integrat...
Genetic Diversity and Population Structure of Farmed Longfin Batfish (Platax teira) in the South China Sea [0.03%]
南海养殖长鳍鱂鱼(Platax teira)的遗传多样性和群体结构
Yayang Gao,Baosuo Liu,Huayang Guo et al.
Yayang Gao et al.
Background: Longfin batfish (Platax teira) is an important economic species in southern China. In recent years, its wild population has significantly declined due to overfishing. Around 2015, breakthroughs in the artifici...
Rare Duplication in the RYR1 Gene Causing Malignant Hyperthermia and Clinical Variability [0.03%]
RYR1基因罕见重复序列导致恶性高热及临床表现多变性
Brandow W Souza,Guilherme L Yamamoto,Isabela A Zogbi et al.
Brandow W Souza et al.
Background/Objectives: Variants in the RYR1 gene are associated mainly with Malignant Hyperthermia. Missense variants are largely the most common, while insertions and duplications account for less than 10%. We aimed to investigate the effe...
Case Reports
Genes. 2025 Oct 24;16(11):1252. DOI:10.3390/genes16111252 2025
Genome-Wide Identification of the PAL Gene Family in Camellia nitidissima and Functional Characterization of CnPAL1 Gene by In Vitro Expression [0.03%]
山茶凝萃种PAL基因家族的全基因组鉴定及CnPAL1体外表达功能分析
Hexia Liu,Bo Li
Hexia Liu
Background: PAL genes are crucial for plant growth and stress response, yet studies on the PAL gene family in Camellia nitidissima are sparse. Methods: The PAL gene family was screened from the entire genome of C. nitidissima, and their phy...
Genetically Confirmed Familial Case of Nonsyndromic Cardiac Progeria Caused by the LMNA p.Asp300Asn Variant with Presumed Gonadal Mosaicism: Phenotypic Comparison with Previously Reported Patients [0.03%]
遗传确认的LMNA p.Asp300Asn变异导致的非综合症性心脏早衰家族病例，并假设生殖细胞嵌合体：与先前报道的患者的表型比较
Ekaterina Nuzhnaya,Margarita Sharova,Uliana Chubykina et al.
Ekaterina Nuzhnaya et al.
We describe the first genetically confirmed familial case of nonsyndromic cardiac progeria caused by the LMNA NM_170707.4:c.898G>A (p.Asp300Asn) variant, with evidence suggesting gonadal mosaicism as the mechanism of inheritance. The proban...
Case Reports
Genes. 2025 Oct 22;16(11):1250. DOI:10.3390/genes16111250 2025
Comparative Analysis of Chloroplast Genome Sequences and Phylogeny in Three Macadamia integrifolia Cultivars [0.03%]
三种Macadamia integrifolia栽培品种的叶绿体基因组序列比较分析及亲缘关系研究
Jihua Guo,Zhuanmiao Kang,Zhongchun Xiao et al.
Jihua Guo et al.
Background/Objectives: Macadamia integrifolia is a valuable subtropical fruit tree, yet genomic studies on its cultivars are limited. This study aims to elucidate the chloroplast genome features, variations, and phylogenetic relationships o...
Comparative Study
Genes. 2025 Oct 22;16(11):1248. DOI:10.3390/genes16111248 2025
Molecular Characterization and Expression Patterns of Sox3 and Sox30 Genes and Response to Exogenous Hormones in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis) [0.03%]
中国甲鱼Sox3和Sox30基因的分子特征、表达模式及外源激素对其诱导作用的研究
Kailin Xiao,Yue Li,Tong Ren et al.
Kailin Xiao et al.
Background/objectives: The Sox transcription factor family is critical for gonadal development and sex differentiation in animals, yet its roles in chelonians, particularly in the Chinese soft-shelled turtle (Pelodiscus s...
Rare Genetic Variants Underlying Primary Immunodeficiency: Clinical, Pulmonary, and Genetic Insights from Two Pediatric Cases [0.03%]
原发性免疫缺陷的罕见基因变异：两例儿科病例的临床、肺部和遗传学见解
Nurgul Sikhayeva,Svetlana Volodchenko,Elena Kovzel et al.
Nurgul Sikhayeva et al.
Background/objectives: Inborn errors of immunity (IEIs), formerly known as primary immunodeficiency disorders, are a heterogeneous group of genetic diseases characterized by recurrent infections and multisystem involvemen...
Case Reports
Genes. 2025 Oct 22;16(11):1247. DOI:10.3390/genes16111247 2025