A Rare Case of Childhood Glaucoma Resulting from Anterior Segment Dysgenesis Associated with a Homozygous Mutation in the CPAMD8 Gene [0.03%]
CPAMD8基因纯合突变所致前段发育不良性婴幼儿型青光角膜葡萄肿一例报告
Nevyana Veleva-Krasteva,Kiril Genov,Kunka Kamenarova et al.
Nevyana Veleva-Krasteva et al.
The term "childhood glaucoma" summarizes a heterogeneous group of diseases characterized by elevated intraocular pressure and associated optic nerve damage. Secondary glaucoma may develop based on non-acquired ocular anomalies, the most com...
Case Reports
Genes. 2026 Apr 21;17(4):494. DOI:10.3390/genes17040494 2026
Genetic Characterization and Statistical Interpretation of 16 STR Markers in South-West Bulgaria: Implications for Forensic Identification and Kinship Analysis [0.03%]
保加利亚西南部16个基因座的遗传特征和统计学分析在法医识别和亲缘关系鉴定中的意义
Vera Djeliova,Bogdan Mirchev,Ekaterina Angelova et al.
Vera Djeliova et al.
Background/Objectives: The widespread adoption of short tandem repeat (STR) marker technology in genetic analysis has led to the collection of substantial STR data from diverse populations. Allele-frequency data provide robust forensic util...
Genetic Identification of Human Skeletal Remains in Forensic Context: A Review [0.03%]
法医领域人体骨骼残骸的基因识别研究进展
Laura Cainé,Madalena Henriques,Adelina Rohovska et al.
Laura Cainé et al.
Background/Objectives: Genetic identification of human skeletal remains plays a pivotal role in forensic investigations when other traditional or primary methods are not appropriate. Decomposition, storage and environmental conditions often...
Shangjia Li,Zhimo Zhu,Chen Yang et al.
Shangjia Li et al.
Background/objectives: Regulated cell death (RCD), a process that relies on a series of molecular mechanisms, can be targeted to eliminate superfluous, irreversibly damaged, and potentially harmful cells. In this research...
Genetic Diversity and Phylogenetic Relationships Among Accessions of Pediomelum tenuiflorum (Pursh) A.N. Egan [0.03%]
基于ISSR技术的细花钟根萍资源遗传多样性及亲缘关系分析
Cynthia O Anukege,Mark Schoenbeck,P Roxanne Kellar
Cynthia O Anukege
Background: Differentiating plant species is complex, complicated by morphological similarities that confound species' delineation. For hundreds of years, researchers have used herbarium specimens to study plant morpholog...
Genome-Wide Identification of the IDD Gene Family in Soybean (Glycine max) and Their Expression Profiles in Response to Drought, Salt Stress, and Different Photoperiod Conditions [0.03%]
大豆(IDD基因家族的全基因组鉴定及其对干旱、盐胁迫和不同光周期的响应表达谱分析)
Rouxing Li,Zixiang Ning,Zhihui Dong et al.
Rouxing Li et al.
Background: INDETERMINATE DOMAIN proteins (IDDs) are a plant-specific transcription factor family, and members of this family play crucial roles in regulating growth and development as well as environmental adaptation. However, a comprehens...
Dual-Caspase-Mediated Apoptosis Underlies Peritoneal Cell-Free DNA Release After PD-Related Peritonitis [0.03%]
PD相关性腹膜炎后腹腔细胞无菌dna释放由双重半胱天冬酶介导的凋亡所致
Grazia Maria Virzì,Sabrina Milan Manani,Matteo Marcello et al.
Grazia Maria Virzì et al.
Background/Objectives: Cell-free DNA (cfDNA) is released into the circulation during inflammation-driven cellular injury and regulated cell death. Elevated cfDNA concentrations have been reported in several clinical settings, including chro...
Effect of DNA Methylation Modulators on UV Damage Formation and Repair [0.03%]
DNA甲基化调节剂对紫外线损伤形成及修复的影响研究
Kyle Jones,Rishav Rajbhandari,Wentao Li
Kyle Jones
Background/Objectives: DNA methylation is a key epigenetic modification involved in regulating many cellular processes, including gene expression and the maintenance of genome stability. Ultraviolet (UV) radiation induces DNA damage in the ...
An Integrative Network Analysis Framework for Identifying Altered Glycosylation Pathways Associated with Autism Spectrum Disorder [0.03%]
一种综合网络分析框架用于识别自闭症谱系障碍相关的异常糖基化途径
Anup Mammen Oommen,Marie Morel,Stephen Cunningham et al.
Anup Mammen Oommen et al.
Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by heterogeneous behavioral symptoms and systemic comorbidities, including immune and gastrointestinal dysfunctions. Emerging studies suggest that g...
A Novel Col4a5-G814fs Knock-In Mouse Model Reveals Phenotypic Heterogeneity Among Truncating COL4A5 Mutations in X-Linked Alport Syndrome [0.03%]
一个新的Col4a5-G814fs敲入小鼠模型揭示了X连锁Alport综合征中COL4A5截断突变的表型异质性
Yingqi Lin,Lei Sun,Mengying Li et al.
Yingqi Lin et al.
Background/Objectives: X-linked Alport syndrome (XLAS) arises from pathogenic variants in COL4A5. Truncating variants are generally classified as severe, but whether clinically meaningful heterogeneity exists within this group remains uncle...