Complete Mitochondrial Genome of Phoxinus grumi (Cypriniformes: Leuciscidae): Characterization and Phylogenetic Position [0.03%]
鱼类线粒体基因组及其系统发育地位研究——基于光唇鱼属的完整线粒体基因组分析
Hongxiong Chang,Wei Guo,Ping Yang et al.
Hongxiong Chang et al.
Background: Phoxinus grumi, a small leuciscid fish endemic to the Turpan Basin in Xinjiang, China, has long been the subject of taxonomic disputes, hindering accurate species identification and the understanding of its ev...
From Genome to Pharmacome: Current Status and Future Perspectives of Multi-Omics Integration in Traditional Chinese Medicine Research [0.03%]
从基因组到药典：多组学整合在中医药研究中的现状与未来展望
Tengfei Yu,Changting Chen,Peng Hu et al.
Tengfei Yu et al.
High-throughput sequencing and multi-omics are transforming Traditional Chinese Medicine (TCM) research from empirical descriptions toward data-driven mechanistic analyses. Unlike earlier systems pharmacology frameworks that relied primaril...
CMSV: Long-Read-Based Structural Variation Detection Through a CNN-Mamba Model [0.03%]
基于长读的通过CNN-Mamba模型的结构变异检测(CMSV)
Song Cheng,Hongbing Ma
Song Cheng
Background/Objectives: Structural variations are important forms of genomic variation and are closely related to genomic diversity and many human diseases. Long-read sequencing has improved the ability to detect structural variations in com...
Building CRISPR-Based Gene-Editing Platforms for Personalized Medicine: The Next Step in Interventional Genetics [0.03%]
基于CRISPR的基因编辑平台的构建助力精准医疗：干预遗传学的下一个步骤
Sebastian Hernandez Rodriguez,Toshifumi Yokota
Sebastian Hernandez Rodriguez
Recent advances in CRISPR technology have expanded beyond traditional double-strand break-based genome editing to include base editors and prime editors, enabling precise and programmable sequence modifications. This evolution marks a shift...
From Bench to Insight: Rapid Pathogen Genomic Surveillance Workflow for SARS-CoV-2 and Emerging Pathogens [0.03%]
从实验室到见解：SARS-CoV-2和其他新发病原体的快速基因组监测工作流
Chelsea Zimmer,Selena McVay,Keely Starke et al.
Chelsea Zimmer et al.
Background/Objectives: Clinical surveillance of infectious diseases caused by viruses, such as SARS-CoV-2, is important for effective intervention and preventing potential epidemics or pandemics. The development of cost-effective whole geno...
Qun Wu,Junsheng Sun,Shengfu Yang et al.
Qun Wu et al.
Wheat (Triticum aestivum L.) is a crucial global food crop that plays a central role in agricultural production and food security. The spike number per unit area (SN) is one of the three component factors of grain yield. In this study, we c...
Transcriptomic Analysis Based on RNA-Seq Technology Reveals the Molecular Mechanisms of Sunflower (Helianthus annuus L.) Response to Salt Stress [0.03%]
基于RNA-seq技术的向日葵转录组分析揭示了其响应盐胁迫的分子机制
Yanfang Zhang,Jiaxin Xie,Shuchun Guo et al.
Yanfang Zhang et al.
Background/Objectives: Sunflower (Helianthus annuus L.) is one of the four major oil crops worldwide and possesses strong stress tolerance. However, salt stress remains limiting in the improvement of sunflower yield and quality. Methods: In...
Forensic Evaluation of the Ion AmpliSeq MH-74 Microhaplotype Panel in the Portuguese Population [0.03%]
Ion AmpliSeq MH-74微卫星基因型在葡萄牙人群中的法医学评价
Rui Nascimento,Heloísa Afonso Costa,Eugénia Cunha et al.
Rui Nascimento et al.
Background/Objectives: Microhaplotypes have emerged as promising genetic markers for forensic applications, combining low mutation rates with high polymorphic information. However, population data remain limited for several regions, includi...
Identification of the Genetic Characteristics of Copy Number Variation Regions in Diverse Goat Populations [0.03%]
识别山羊不同群体拷贝数变异区域的遗传特征
Wenze Li,Yixin Su,Can Liu et al.
Wenze Li et al.
Background: Copy number variation (CNV) is an important class of structural variations (SVs) that contribute to phenotypic diversity and environmental adaptation in animals. However, large-scale population-level analyses ...
Identifying Single-Cell Expression Quantitative Trait Loci Using a Bootstrap Penalized Hurdle Model [0.03%]
利用Bootstrap惩罚 hurdle模型识别单细胞表达定量特征位点
Dongyuan Wu,Susmita Datta
Dongyuan Wu
Background: Expression quantitative trait loci (eQTL) analysis links genetic variants to gene expression levels, helping to uncover how genetic variation contributes to gene regulation. While traditional eQTL analyses rel...