Stent angioplasty in patients with vertebral artery ostial stenosis: clinical and angiographic outcomes in 525 patients [0.03%]
血管造影证实的椎动脉开口部狭窄的支架成形术临床及影像学结果(525例)
Kamran Hajiyev,Ali Khanafer,Philipp von Gottberg et al.
Kamran Hajiyev et al.
Background: The optimal treatment approach for patients with severe atherosclerotic vertebral artery ostial stenosis (VAOS) is not yet supported by evidence from large-scale studies. Even with optimal medical treatment an...
Fibrinogenase for injection in the treatment of acute ischaemic stroke: a randomised clinical trial [0.03%]
注射用降纤酶治疗急性缺血性脑卒中：随机临床试验
Mengmeng Ma,Jinghuan Fang,Xin Jiang et al.
Mengmeng Ma et al.
Background: Fibrinogenase for injection is an effective antithrombotic agent for eligible patients with acute ischaemic stroke (AIS), but evidence regarding its treatment effects remains limited. This study aimed to evalu...
Early blood pressure lowering and cerebral oedema in thrombolysis-treated stroke: secondary analysis of the ENCHANTED trial [0.03%]
ENCHANTED试验的二次分析：溶栓治疗患者的早期降压与脑水肿的关系
Feifeng Liu,Xinwen Ren,Chen Chen et al.
Feifeng Liu et al.
Background and purpose: Controversy persists over the balance of benefits and harms of early intensive blood pressure (BP) lowering in thrombolysis-treated acute ischaemic stroke (AIS) patients. The BP-control arm of the ...
Monitoring treatment of delayed cerebral ischaemia in unconscious patients after aneurysmal subarachnoid haemorrhage: a prospective multimodal neuromonitoring study [0.03%]
蛛网膜下腔出血后动脉瘤患者的延迟性脑缺血的治疗监测：一项多模式神经监护的前瞻性研究
Michael Veldeman,Stefan Yu Bögli,Ihsane Olakorede et al.
Michael Veldeman et al.
Background: Aneurysmal subarachnoid haemorrhage (SAH) is a life-threatening condition with high morbidity. Delayed cerebral ischaemia (DCI) significantly contributes to secondary injury and poor outcomes. While perfusion ...
Reduced endothelial TAK1 impairs vascular integrity in cerebral small vessel disease via the RIPK1-MLKL signalling pathway [0.03%]
内皮TAK1减少通过RIPK1-MLKL信号途径损害脑小血管疾病中的血管完整性
Jing Yang,Chi Xiao,Ming Yi et al.
Jing Yang et al.
Background: Hypertension stands as a major modifiable risk factor for cerebral small vessel disease (CSVD), driving pathological cerebrovascular rarefaction and blood-brain barrier (BBB) compromise through endothelial dys...
Outcomes of Onyx embolisation as primary treatment for intracranial dural arteriovenous fistulas over the past two decades [0.03%]
过去二十年间奥曲肽栓塞作为颅内硬脑膜动静脉瘘的一线治疗的效果
Xin Su,Zihao Song,Yiguang Chen et al.
Xin Su et al.
Background: Most current studies on Onyx are limited by small sample sizes and often involve its use in combination with other embolic materials, with few investigations specifically evaluating Onyx as a sole embolic agen...
Tenecteplase versus standard care in patients with acute basilar artery occlusion: a multi-centre, prospective, randomised, open-label, blinded endpoint, phase 3, controlled trial [0.03%]
替奈普酶与标准治疗急性基底动脉闭塞的患者的有效性：一项多中心、前瞻性、随机对照三期临床试验
Yunyun Xiong,Fana Alemseged,Zhixin Cao et al.
Yunyun Xiong et al.
Background and purpose: There is a scarcity of evidence of tenecteplase administered within the 24-hour window of acute ischaemic stroke due to basilar artery occlusion (BAO). We sought to assess whether intravenous tenec...
Contact aspiration versus stent retriever thrombectomy for acute basilar artery occlusion (ANGEL-COAST): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint trial [0.03%]
接触式抽吸取栓与支架取栓治疗急性基底动脉闭塞（ANGEL-COAST）：多中心、前瞻性、随机对照、开放标签、盲终点试验的设计和原理
Sun Xuan,Ming Yang,Dapeng Sun et al.
Sun Xuan et al.
Background: Contact aspiration (CA) and stent retriever (SR) thrombectomy are two equally recommended first-line endovascular techniques for treating acute ischaemic stroke due to large vessel occlusion. Whether CA is mor...
Clinical features, treatment and long-term outcomes of hemorrhagic moyamoya disease in children: an extensive follow-up study [0.03%]
儿童出血性烟雾病的临床特征、治疗及长期预后：一项随访研究
Cheng Chen,Gan Gao,Desheng Li et al.
Cheng Chen et al.
Background: Paediatric hemorrhagic moyamoya disease (hMMD) is rare, with unclear clinical features and long-term outcomes owing to limited data. We comprehensively evaluated the clinical characteristics, prognosis and opt...
Association between elevated adiponectin levels and 5-year risk of clinical outcomes in patients with ischaemic stroke [0.03%]
缺血性卒中患者血清脂联素水平与5年临床结局风险之间的关系
Siding Chen,Fanzhen Lin,Jinfeng Yin et al.
Siding Chen et al.
Background: The role of adiponectin (ADPN) in stroke remains debatable, despite its significant impact as a major adipocytokine on cardiovascular (CV) diseases. This study aimed to assess the association between ADPN and ...