Factors associated with infarct volume growth after mechanical thrombectomy in large core infarction: ANGEL-ASPECT insights [0.03%]
ANGEL-ASPECT研究中大梗死核心患者机械取栓后梗死体积扩大的相关因素分析
Longhui Zhang,Yufan Liu,Fangguang Chen et al.
Longhui Zhang et al.
Background: Infarct volume growth (IVG) correlates with outcomes and may represent a prognostic imaging biomarker in acute ischaemic stroke due to anterior circulation large vessel occlusion (LVO). This study aims to iden...
30 years of thrombolysis for ischaemic stroke: expanded agents, widened windows and accelerated delivery [0.03%]
溶栓治疗缺血性卒中的30年：药物扩大、时间窗延长以及加速给药
Bowei Zhang,Shuya Li,Xia Meng et al.
Bowei Zhang et al.
Over the past three decades, thrombolytic therapy for acute ischaemic stroke has evolved dramatically since the landmark National Institute of Neurological Disorders and Stroke (NINDS) trial in 1995, which formally established recombinant t...
Heterogeneity of cerebral small vessel disease based on imaging markers in a community-based population [0.03%]
基于影像标志物的社区人群中脑小血管疾病的异质性研究
Yuxian Li,Dandan Liu,Yingying Yang et al.
Yuxian Li et al.
Background: The heterogeneity of cerebral small vessel disease (CSVD) within community populations remains underexplored. In this study, we aimed to establish an imaging biomarker-based research paradigm to investigate CS...
Mechanisms of disorders of consciousness based on source-level microstate characteristics under deep brain stimulation neuromodulation [0.03%]
深脑刺激神经调控下基于源水平微状态特征的意识障碍机制研究
Tianqing Cao,Yihua Wang,Bin Jiang et al.
Tianqing Cao et al.
Background: Improving the efficacy of neuroregulatory treatments for disorders of consciousness (DOCs) remains a significant challenge. Changes in brain spatiotemporal dynamics reveal the underlying mechanisms of brain ne...
RIC-specific cytoprotective profile mediated by microglia in a mouse model of acute ischaemic stroke [0.03%]
小鼠急性缺血性卒中模型中微胶质细胞介导的RIC特异性细胞保护表型研究
Coral Torres-Querol,Gloria Arqué,Francisco Purroy
Coral Torres-Querol
Background: Remote ischaemic conditioning (RIC) is an endogenous neuroprotective strategy involving repeated, transient occlusion of a limb artery to reduce ischaemic injury at a distant site. We investigated the effects ...
Yongjun Wang,Bowei Zhang,Xuewei Xie
Yongjun Wang
Over the past three decades, the development of evidence-based medicine (EBM) has brought significant opportunities to the advancement of clinical practice in stroke medicine. Substantial EBM evidence has transformed clinical practice in mu...
Letter to the editor: risk factors for cervical artery dissection - a systematic review with meta-analysis [0.03%]
写给编辑室：颈动脉夹层的风险因素-一项系统性回顾和荟萃分析
Joshua Plener,L Rachid Salmi,J David Cassidy et al.
Joshua Plener et al.
Loberamisal for Acute Ischaemic Stroke (LAIS): a multicentre, randomised, double-blind, parallel, placebo-controlled phase III clinical trial [0.03%]
洛博拉米沙尔治疗急性缺血性卒中的多中心随机双盲平行对照三期临床试验（LAIS研究）
Shuya Li,Xuechun Wang,Baoyu Feng et al.
Shuya Li et al.
Background and objectives: Loberamisal, a novel agent that dissociates the post-synaptic density protein 95/neuronal nitric oxide synthase complex and potentiates the α2-containing γ-aminobutyric acid type A receptors, ...
Chinese expert consensus on the treatment and diagnosis of moyamoya disease and moyamoya syndrome (2024) [0.03%]
中国 moyamoya 病和 moyamoya 综合征诊断和治疗专家共识（2024）
Wei Ni,Jiabin Su,Yuchao Fei et al.
Wei Ni et al.
Aim: Moyamoya disease (MMD) is a chronic, occlusive cerebrovascular disorder with no unified management guidelines. This consensus aims to provide updated, evidence-based recommendations for the diagnosis and treatment of...
Burden of stroke and its subtypes in young adults in Asia, 1990-2021: risk factors and future predictions [0.03%]
1990年至2021年亚洲年轻人卒中及其亚型的疾病负担：危险因素及未来预测
Wenbo Li,Qirui Guo,Cong Gao et al.
Wenbo Li et al.
Stroke remains a major global public health challenge, with persistent disparities in its burden across countries, and an increasing burden among young adults aged 15-49 has emerged as a growing concern. However, comprehensive evaluations o...