Cough reflex testing for dysphagia severity and pneumonia risk after acute stroke: a prospective observational study [0.03%]
急性卒中后咳嗽反射测试评估吞咽困难严重程度和肺炎风险的前瞻性观察研究
Anne Jung,Bendix Labeit,Stephan Oelenberg et al.
Anne Jung et al.
Introduction: Poststroke dysphagia and impaired cough reflex contribute to aspiration and pneumonia, yet the clinical value of cough reflex testing remains unclear. ...
Chinese stroke association guidelines on construction of direct transfer to angiography suite [0.03%]
中国卒中协会关于构建直接送至导管手术室的指南
Yunyun Xiong,Marc Ribo,Bruce C V Campbell et al.
Yunyun Xiong et al.
Large vessel occlusion (LVO) is a severe subtype of acute ischaemic stroke, for which endovascular therapy significantly improves clinical outcomes. Expediting time to reperfusion is critical; however, conventional in-hospital workflows bas...
Development and validation of an explainable prediction model for post-stroke epilepsy in patients with ischaemic stroke following mechanical thrombectomy: a multicentre retrospective cohort study [0.03%]
缺血性脑卒中机械取栓术后出血转化致痫预测模型的开发和验证：多中心回顾性队列研究
Zongzhi Jiang,Zhanhao Mo,Mingyang Du et al.
Zongzhi Jiang et al.
Objective: In this retrospective multicentre cohort study, we aimed to develop and validate an interpretable machine learning (ML) model for early post-stroke epilepsy (PSE) prediction in patients who underwent mechanical...
Endothelial dysfunction mediates inflammation-driven poor prognosis in symptomatic intracranial atherosclerosis stenosis [0.03%]
血管内皮功能不全介导了症状性颅内动脉粥样硬化狭窄的炎症相关不良预后
Qiong Wu,Ruoyu Li,Jinfeng Yin et al.
Qiong Wu et al.
Introduction: Systemic inflammation is associated with poor outcomes in symptomatic intracranial atherosclerotic stenosis (sICAS); however, the underlying mechanisms remain unclear. We investigated whether urinary albumin...
Piezo1 mechanosensitive ion channel in macrophages: a potential therapeutic target for intracerebral haemorrhage [0.03%]
巨噬细胞中的Piezo1机械敏感性离子通道是颅内出血的潜在治疗靶点
Renate Ma,Ashley Aguillard,Zhidan Xiang et al.
Renate Ma et al.
Piezo1 is a mechanoreceptor cation channel that responds to various physical and environmental stimuli to facilitate an influx of cations, thereby converting physical or chemical triggers into electrochemical activity. Highly expressed on t...
Rethinking the management of small unruptured intracranial aneurysms: risk balance and emerging strategies [0.03%]
重新思考小型未破裂颅内动脉瘤的管理：风险平衡和新兴策略
Bing Zhao,Qingyuan Liu,Christopher S Ogilvy
Bing Zhao
Small unruptured intracranial aneurysms (UIAs) are increasingly detected by imaging modalities widely used in clinical practice. The low rupture risk of small UIAs contrasts with the substantial proportion of small aneurysms in ruptured cas...
Individual heterogeneity in neuroimaging markers of functional outcomes in patients with acute ischaemic stroke [0.03%]
急性缺血性卒中患者的神经影像功能预后的个体异质性
Luo Yi,Hui Tang,Hao Liu et al.
Luo Yi et al.
Background: This study aimed to investigate the heterogeneity of topographic and connectomic mechanisms underlying diverse functional outcomes in patients with acute ischaemic stroke. ...
Renal function and effect of early antihypertensive therapy in acute ischaemic stroke: a subgroup analysis of the CATIS-2 trial [0.03%]
中国急性缺血性卒中早期降压治疗的肾脏效应：CATIS-2试验的亚组分析
Dacheng Liu,Yufei Wei,Xuewei Xie et al.
Dacheng Liu et al.
Background: The role of renal function in patients with acute ischaemic stroke (AIS) receiving blood pressure (BP) lowering therapy remains incompletely understood. In this prespecified subgroup analysis of the CATIS-2 tr...
Tenecteplase versus alteplase in elderly stroke: a post hoc analysis of the AcT trial [0.03%]
重组组织型纤溶酶原激活剂与替奈普酶治疗老年急性缺血性脑卒中的疗效和安全性：ACT试验的事后分析
Taha Aslan,Mohamed AlShamrani,Brian Buck et al.
Taha Aslan et al.
Background: Stroke rates rise steeply with age but data on tenecteplase in patients ≥80 years remain limited. This post-hoc analysis of the AcT trial compared tenecteplase with alteplase in this population. ...
Machine learning models for outcome prediction of patients with ischaemic stroke undergoing reperfusion therapy: a systematic review and meta-analysis [0.03%]
用于评估接受再灌注治疗的缺血性卒中患者预后的机器学习模型系统评价和Meta分析
Song He,Yijie Gao,Quandan Tan et al.
Song He et al.
Background: Reperfusion therapy, including thrombolysis and thrombectomy, is crucial for ischaemic stroke treatment. However, patient outcomes often remain suboptimal. Conventional regression models show limited accuracy ...