Intravenous tenecteplase before endovascular thrombectomy in patients with acute basilar artery occlusion within 4.5-24 hours: study protocol and rationale [0.03%]
急性基底动脉闭塞患者在发病4.5-24小时内进行血管内血栓抽吸前应用替奈普酶静脉给药：研究方案与原理说明
Rui Li,Thanh Nguyen,Chunrong Tao et al.
Rui Li et al.
Background and purpose: One clinical trial demonstrated the beneficial effect of intravenous tenecteplase for large vessel occlusion patients not undergoing endovascular thrombectomy (EVT) within 4.5-24 hours. However, fo...
Access to mechanical thrombectomy for stroke in the UK: the unacceptable postcode lottery [0.03%]
英国卒中患者接受机械取栓治疗情况postcode抽奖游戏的结果不可接受：英国卒中患者接受机械取栓治疗情况不容乐观
Soma Banerjee,Kyriakos Lobotesis,Joseph Kwan et al.
Soma Banerjee et al.
Sox10 glial-neuron nuclear communication mediates anti-apoptosis neuroprotection after ischaemic stroke [0.03%]
Sox10胶质细胞-神经元核通讯在缺血性脑卒中后抗凋亡神经保护中的作用
Maojiao Huang,Xinye Huang,Yunru Chen et al.
Maojiao Huang et al.
Background: Neuronal apoptosis is a hallmark of ischaemic stroke, yet effective neuroprotective therapies remain scarce. Recent studies suggest that Sox10-lineage cells (SOL) can transfer nuclear material to neurons. Howe...
Efficacy and safety of edaravone sublingual tablet for patients with cerebral small vessel disease-related cognitive impairment: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial [0.03%]
edaravone舌下片治疗脑小血管病相关认知障碍患者的有效性和安全性：多中心随机双盲安慰剂对照试验方案
Qing Ye,Weidong Ling,Haifeng Chen et al.
Qing Ye et al.
Background: Cerebral small vessel disease (CSVD) represents a leading aetiology of vascular cognitive impairment, yet effective treatments for CSVD-related cognitive impairment (CSVD-CI) are limited. Although edaravone ha...
Long-term mortality associated with incidental unruptured intracranial aneurysms in neurologically healthy Japanese adults: the Kashima scan study [0.03%]
日本神奈川县成年人无症状颅内动脉瘤的长期相关死亡率：神户扫描研究
Atsushi Ogata,Kohei Suzuyama,Tatsumi Hirotsu et al.
Atsushi Ogata et al.
Background and purpose: With the widespread use of MRI, there has been an increase in the frequency of incidental detection of unruptured intracranial aneurysms (UIAs); however, the mortality rates and cause of death in a...
AI-Based STroke Risk fActor Classification and Treatment (ABSTRACT) study [0.03%]
基于人工智能的卒中危险因素分类和治疗(ABSTRACT)研究
William Heseltine-Carp,Aishwarya Kasabe,Megan Courtman et al.
William Heseltine-Carp et al.
Background: Stroke is a leading cause of death and disability worldwide, costing the UK approximately £26 billion annually. While lifestyle modification and preventative medications reduce risk, 30% of patients with stro...
Effect of a regional guideline-education initiative on dual antiplatelet therapy use in minor non-cardioembolic stroke: a pre-post analysis from the Shanghai Stroke Service System [0.03%]
上海卒中服务系统缺血性小卒中或短暂性脑缺血发作双联抗血小板治疗的地区指南教育干预前后分析研究
Sha Han,Jiawen Xu,Yanan Xie et al.
Sha Han et al.
Background: Dual antiplatelet therapy (DAPT) reduces recurrent stroke in patients with minor non-cardioembolic ischaemic stroke or high-risk transient ischaemic attack (TIA). However, real-world prescribing remains hetero...
Thrombus magnetic susceptibility: implications for distal embolisation risk in endovascular therapy [0.03%]
血栓磁化率与血管内治疗远端栓塞风险的关系研究
Jie Chen,Zhe Zhang,Ximing Nie et al.
Jie Chen et al.
Background: Distal embolisation (DE) is a common complication following endovascular treatment (EVT) for acute ischaemic stroke. Thrombus magnetic susceptibility may offer predictive insights into DE risk. In this study, ...
Multimodal MRI habitat atlas for personalised re-haemorrhage risk prediction in brainstem cavernous malformations [0.03%]
针对脑干海绵状血管畸形的个性化出血风险预测的多模态MRI生境图谱
Haohuai Gui,Xuchen Dong,Zongze Li et al.
Haohuai Gui et al.
Objective: To develop an MRI habitat atlas that is robust across different haemorrhage stages for haemorrhagic brainstem cavernous malformations (BSCMs) and to integrate habitat-derived imaging biomarkers with clinical va...
Efficacy and safety of heparin in preventing embolic events during transradial cerebral angiography: a randomised controlled trial [0.03%]
预防经桡动脉脑血管造影期间栓塞事件的疗效和安全性的随机对照试验HEPARIN研究
Chenchen Liu,Gang Deng,Yihui Wang et al.
Chenchen Liu et al.
Background: Transradial access has become an increasingly preferred approach for cerebral angiography. However, embolic events, often clinically silent, remain a frequent concern. Despite routine use, the efficacy and saf...