Efficacy of immediate anti-hypertensive treatment in patients with acute ischaemic stroke stratified by mean arterial pressure and pulse pressure: a secondary analysis of the China Antihypertensive Trial in Acute Ischemic Stroke trial [0.03%]
根据中国急性缺血性卒中降压治疗研究（CATIS）的亚组分析评价不同血压分层急性缺血性卒中患者立即降压治疗的有效性
Ming Wang,Shiguang Zhu,Jiayi Long et al.
Ming Wang et al.
Background: Whether mean arterial pressure (MAP) and pulse pressure (PP), two indicators of cerebral perfusion, could guide the selection of anti-hypertensive strategies after acute ischaemic stroke remains uncertain. Our...
Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease [0.03%]
外周血GATA2表达影响 moyamoya病RNF213突变的外显率和临床严重程度
Yohei Mineharu,Takahiko Kamata,Mei Tomoto et al.
Yohei Mineharu et al.
Background: The p.R4810K founder mutation in the RNF213 gene confers susceptibility to moyamoya disease (MMD) and non-MMD intracranial artery disease. However, penetrance is incomplete, and the underlying molecular mechan...
Intracerebral haemorrhage laterality and associations with mood and pain: a MISTIE III substudy [0.03%]
颅内出血侧别与情绪和疼痛的关系：来自MISTIE III亚组的研究结果
Dawson C Cooper,Efrat Abramson,Wendy C Ziai et al.
Dawson C Cooper et al.
Background: The prognostic significance of the affected hemisphere in haemorrhagic stroke remains uncertain. We aimed to determine the relationship between the affected hemisphere (right or left) and differences in non-mo...
Effect of intravenous alteplase before endovascular therapy for atherothrombotic stroke-related large vessel occlusion: subanalysis of the RESCUE AT-LVO registry [0.03%]
组织型纤溶酶原激活剂静脉给药联合血管内治疗治疗动脉粥样硬化性大血管闭塞性卒中的疗效：RESCUE AT-LVO注册研究的亚组分析
Hirotaka Hayashi,Satoshi Namitome,Seigo Shindo et al.
Hirotaka Hayashi et al.
Background: Whether intravenous thrombolysis (IVT) should be administered prior to endovascular therapy (EVT) in patients with atherothrombotic stroke-related large vessel occlusion (AT-LVO) remains unclear. This study ai...
Functional outcomes of minimally invasive surgery treatment for patients with small supratentorial spontaneous intracerebral haematoma less than 30 mL: a propensity score matching study [0.03%]
小容量幕上自发性脑内血肿患者微创手术治疗功能预后：倾向性评分匹配研究
Hanyu Sun,Xinqun Luo,Zhang Guo et al.
Hanyu Sun et al.
Background: This study investigated the efficacy of frameless robot-assisted stereotactic aspiration coupled with catheter thrombolysis (SA-CT) in treating supratentorial spontaneous intracerebral haemorrhage (sICH) with ...
E F fects of Y-6 S U blingual Tablets for Pa T ients with Ac U te Ischemic St R ok E (FUTURE): a phase II, randomised, double-blind, double-dummy, placebo-controlled, parallel trial [0.03%]
Y-6滴丸治疗急性缺血性卒中的疗效（未来）：一项II期随机双盲安慰剂对照平行分组临床试验
Yicong Wang,Baoshan Qiu,Ling Guan et al.
Yicong Wang et al.
Background: Acute ischaemic stroke, due to its high mortality and disability rates, imposes a significant economic and social burden worldwide. Typically, endovascular treatment within the therapeutic window is provided t...
Stepwise improvement in intracerebral haematoma expansion prediction with advanced imaging: a comprehensive comparison of existing scores [0.03%]
基于影像学的颅内血肿扩大的预测评分的系统比较研究
Umberto Pensato,Koji Tanaka,Chitapa Kaveeta et al.
Umberto Pensato et al.
Background: We aim to comprehensively assess and compare the predictive performance of haematoma expansion (HE) scores in a homogeneous cohort of acute intracerebral haemorrhage (ICH) patients. ...
Learning curve and embolisation strategy in single-stage surgery combined embolisation and microsurgery for brain arteriovenous malformations: results from a nationwide multicentre prospective registry study [0.03%]
单阶段手术治疗脑动静脉畸形术前栓塞策略和学习曲线的全国多中心前瞻性注册研究结果
Tengfei Yu,Heze Han,Li Ma et al.
Tengfei Yu et al.
Objective: Single-stage surgery combining embolisation and microsurgery has been increasingly used as a stand-alone procedure to cure complex AVMs. This study aimed to investigate the learning curve and embolisation strat...
Young stroke in Bangladesh: addressing rare cases with diagnostic challenges and much-needed solutions [0.03%]
孟加拉国的青年卒中：解决罕见病例的诊断难题和亟需的解决方案
Manisha Das,Md Jubayer Hossain
Manisha Das
Stroke is a leading cause of mortality and morbidity in Bangladesh, and young adults are increasingly affected. Common risk factors include hypertension, diabetes, dyslipidaemia, obesity and smoking, whereas rare causes include haematologic...
Rationale and Study Design to Assess the Efficacy and Safety of Minocycline in Patients with Moderate to Severe Acute Ischaemic Stroke (EMPHASIS) [0.03%]
评估中度至重度急性缺血性卒中患者使用米诺环素的疗效和安全性的合理性和研究设计（EMPHASIS）
Yao Lu,Ling Guan,Meiyang Zhang et al.
Yao Lu et al.
Background: Inflammation and blood-brain barrier disruption may contribute to the pathogenesis of ischaemic stroke. Minocycline was shown to exert anti-inflammatory effects by attenuating microglial activation and protect...