Behavioral state-dependent lateralization of dorsal dentate gyrus c-Fos expression in mice [0.03%]
与行为状态相关的鼠背侧齿状回c-Fos表达侧化现象
Jake T Jordan,M Regis Shanley,Carolyn L Pytte
Jake T Jordan
Hemispheric lateralization is a fundamental organizing principle of nervous systems across taxonomic groups with bilateral symmetry. The mammalian hippocampus is lateralized anatomically, physiologically, and chemically; however, functional...
The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells [0.03%]
饮食类黄酮香豆素亚环烯是一种强烈的人类神经母细胞瘤细胞毒药
Amnah M Alshangiti,Katie L Togher,Shane V Hegarty et al.
Amnah M Alshangiti et al.
Neuroblastoma (NB) is the most common extracranial solid tumor of early childhood; it accounts for approximately 8-10% of all childhood cancers and is the most common cancer in children in the first year of life. Patients in the high-risk g...
A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia [0.03%]
孤儿核受体TLX在神经前体细胞与小胶质细胞相互作用中的作用
Danka A Kozareva,Gerard M Moloney,Alan E Hoban et al.
Danka A Kozareva et al.
Microglia are an essential component of the neurogenic niche in the adult hippocampus and are involved in the control of neural precursor cell (NPC) proliferation, differentiation and the survival and integration of newborn neurons in hippo...
Regulation of cholinergic basal forebrain development, connectivity, and function by neurotrophin receptors [0.03%]
神经生长因子受体调控胆碱能基底前脑的发育、连接和功能
Zoran Boskovic,Sonja Meier,Yunpeng Wang et al.
Zoran Boskovic et al.
Cholinergic basal forebrain (cBF) neurons are defined by their expression of the p75 neurotrophin receptor (p75NTR) and tropomyosin-related kinase (Trk) neurotrophin receptors in addition to cholinergic markers. It is known that the neurotr...
CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain [0.03%]
CRMP2和电压门控离子通道在神经病理性疼痛中的潜在作用
Lindsey A Chew,Rajesh Khanna
Lindsey A Chew
Neuropathic pain represents a significant and mounting burden on patients and society at large. Management of neuropathic pain, however, is both intricate and challenging, exacerbated by the limited quantity and quality of clinically availa...
Novel rapid-acting antidepressants: molecular and cellular signaling mechanisms [0.03%]
新型快速抗抑郁剂：分子及细胞信号转导机制
Alexandra M Thomas,Ronald S Duman
Alexandra M Thomas
Depression is a chronic, debilitating, and common illness. Currently available pharmacotherapies can be helpful but have several major drawbacks, including substantial rates of low or no response and a long therapeutic time lag. In pursuit ...