Ruchi Umargamwala,Jantina Manning,Julian M Carosi et al.
Ruchi Umargamwala et al.
Autophagy is a fundamental cellular recycling process that maintains homeostasis during animal development and under nutrient-limiting conditions. In our previous work, we employed autophagy-dependent cell death (ADCD) in the obsolete Droso...
Correction: Long range inter-chromosomal interaction of Oct4 distal enhancer loci regulates ESCs pluripotency [0.03%]
Byoung-San Moon,David Huang,Fan Gao et al.
Byoung-San Moon et al.
Published Erratum
Cell death discovery. 2026 Apr 14;12(1):183. DOI:10.1038/s41420-026-02993-4 2026
Jana Leuenberger,Grischa Ott,Thomas Nevian et al.
Jana Leuenberger et al.
A vital question in neuroscience is whether and how efficiently cellular models may be differentiated into functional neuronal cells in culture. Despite the frequent use of the human neuroblastoma cell line SH-SY5Y, differentiation protocol...
Correction: CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells [0.03%]
Chuyun Chen,Fubin Zhang,Jiayi Shen et al.
Chuyun Chen et al.
Published Erratum
Cell death discovery. 2026 Apr 14;12(1):184. DOI:10.1038/s41420-026-03008-y 2026
Targeting the ODC1-YBX1 axis reverses gastric cancer chemoresistance via transcriptional control of SLC7A11-mediated ferroptosis [0.03%]
Ruiqi Li,Shantanu Baral,Fanyu Zhao et al.
Ruiqi Li et al.
Gastric adenocarcinoma (STAD), a leading cause of cancer mortality, faces major therapeutic challenges due to intrinsic and acquired chemoresistance. Chemoresistance is intricately linked to ferroptosis.Elucidating the mechanisms of chemoth...
Bon appétit, your phagocyte [0.03%]
Dilara C Ozkocak,Jascinta P Santavanond,Maria C Tanzer et al.
Dilara C Ozkocak et al.
Every day, billions of cells in the human body undergo apoptosis as part of normal tissue turnover. The swift clearance of these dying cells by phagocytes is an essential process to limit the release of intracellular contents that can disru...
BIRC3/CAV1 co-expression drives GBM aggressiveness as a prognostic signature and therapeutic vulnerability [0.03%]
BIRC3/CAV1共表达作为预后标志物驱动胶质母细胞瘤的恶性表型及潜在治疗靶点
Sara Franceschi,Mariangela Morelli,Francesca Lessi et al.
Sara Franceschi et al.
Glioblastoma (GBM) is an incurable tumor where temozolomide (TMZ) resistance limits survival, even in MGMT-methylated patients. To improve stratification, we used NAD(P)H-FLIM to profile TMZ response in 35 patient-derived explants, integrat...
Shaorui Niu,Pang Yang,Yuyang Yao et al.
Shaorui Niu et al.
Ferroptosis, a form of regulated cell death, plays a pivotal role in the development and treatment of cancer because of its impact on tumor cell proliferation, differentiation, and resistance to chemotherapy. NT5DC2, a gene associated with ...
Oncoprotein CYB561, acting in IRE1-XBP1-SREBF1 and FAK-ERK pathway, promotes breast cancer lipogenesis and progression [0.03%]
致癌蛋白CYB561通过IRE1-XBP1-SREBF1和FAK-ERK通路促进乳腺癌脂质生成及发展
Xiaochen Yang,Yukai Tao,Yan Xu et al.
Xiaochen Yang et al.
Breast cancer (BC) heterogeneity, particularly in triple-negative (TNBC) and HER2-positive subtypes, underpins therapeutic challenges and cancer-related mortality worldwide. Here, we identify the transmembrane oxidoreductase CYB561 as a piv...
Long term administration of selective NMDA GluN2B receptor blocker Ro25-6981 attenuates neurodegeneration in mouse model of spinocerebellar ataxia type 1 (SCA1) [0.03%]
选择性NMDA GluN2B受体拮抗剂Ro25-6981长期给药减轻小鼠脊髓小脑共济失调1型(SCA1)模型神经退行性病变
Olga S Belozor,Alexandra G Mileiko,Lyudmila D Mosina et al.
Olga S Belozor et al.
Spinocerebellar ataxia type 1 (SCA1) is caused by a CAG expansion in the gene that encodes the protein Ataxin1. Accumulation of the mutant protein in cells leads to degeneration of the cerebellum and brainstem, resulting in ataxia and culmi...