Marie Minet,Amila Beganovic,Shusruto Rishik et al.
Marie Minet et al.
During restricted timeframes in Drosophila development, re-replication occurs as physiological process causing the known developmental gene amplification in Drosophila. Gene amplification has also been found during differentiation in human ...
Cytokine-induced expandable memory NK cells with significant metabolic, epigenetic remodeling, and persistence properties [0.03%]
细胞因子诱导的具有显著代谢、表观遗传重塑和持久性特性的可扩增记忆NK细胞
Hongye Wang,Jingwei Tu,Yi Luo et al.
Hongye Wang et al.
Recent investigations have indicated that NK cells induced overnight with IL-12/15/18 cytokines possess memory-like characteristics (refers as CIML NK, cytokine induced memory-like NK cells), demonstrating enhanced effector function and pro...
PIN1 enhances SUMOylation of YAP1 and inhibits ferroptosis via autophagy-dependent degradation of ACSL4 in cervical cancer [0.03%]
PIN1通过自噬依赖的ACSL4降解在宫颈癌中促进YAP1的SUMO化并抑制铁死亡
Dan Liao,Lijuan Shi,Yumeng Cui et al.
Dan Liao et al.
Cervical cancer (CC) is a prevalent malignancy threatening women's health. Due to its complex pathogenesis and tumor heterogeneity, it is urgent to thoroughly investigate its pathological mechanisms. Based on the TCGA database, the expressi...
Marina Campos Rocha,Neta Shlezinger,Jean-Pierre Gangneux et al.
Marina Campos Rocha et al.
Feihong Ren,Yudian Wang,Yufei Zhang et al.
Feihong Ren et al.
The global incidence and prevalence of kidney diseases continue to rise, posing a serious public health challenge. SIRT6 is an NAD⁺-dependent histone deacetylase with broad essential regulatory roles across various pathophysiological proce...
Correction: A positive feedback loop between TKT and c-Myc drives TACE resistance in hepatocellular carcinoma [0.03%]
Correction：TKT和c-MYC之间的正反馈环驱动肝细胞癌中TACE抵抗
Yifu Xiao,Mingyu Liu,Ying Zhou et al.
Yifu Xiao et al.
Published Erratum
Cell death discovery. 2026 Jul 15;12(1):308. DOI:10.1038/s41420-026-03216-6 2026
Technical and regulatory challenges in cell therapy products: lessons from unsuccessful IND and BLA/NDA approvals [0.03%]
有关细胞治疗产品的技术及法规难题——未获成功的IND和BLA/NDA提交案例分析启示
Dongmei Han,Jinping Xie,Yufang Shi et al.
Dongmei Han et al.
Correction: NLRP3-mediated pyroptosis aggravates pressure overload-induced cardiac hypertrophy, fibrosis, and dysfunction in mice: cardioprotective role of irisin [0.03%]
纠正：NLRP3介导的焦亡加重压力超负荷诱导的小鼠心肌肥厚、纤维化和功能障碍： Irisin的心脏保护作用
Rongchuan Yue,Zaiyong Zheng,Yu Luo et al.
Rongchuan Yue et al.
Published Erratum
Cell death discovery. 2026 Jul 15;12(1):309. DOI:10.1038/s41420-026-03177-w 2026
KIF14 silencing suppresses cell proliferation and enhances chemosensitivity by modulating 53BP1 nucleocytoplasmic shuttling in non-WNT/non-SHH medulloblastoma [0.03%]
KIF14沉默通过调节非WNT /非SHH髓母细胞瘤中53BP1的核胞质转运来抑制细胞增殖并增强化疗敏感性
Huangyi Fang,Tao Xu,Wei Wen et al.
Huangyi Fang et al.
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. The non-WNT/non-SHH subtypes (Groups 3 and 4) exhibit high genetic heterogeneity and limited therapeutic options. Kinesin family member 14 (KIF14) is selectively expre...
Piceatannol as a safe senotherapeutic: ameliorating senescence-associated markers in a radiation-induced murine model [0.03%]
白杨茋作为安全的衰老治疗药物：改善辐射诱导的小鼠模型中与衰老相关的标志物
Alessia Ambrosino,Claudia Moriello,Nicola Alessio et al.
Alessia Ambrosino et al.
Cellular senescence is a key driver of age-associated tissue dysfunction through the secretion of pro-inflammatory and pro-senescent factors (SASP). Among these, insulin-like growth factor binding proteins (IGFBPs) have emerged as causal me...