Verapamil reduces coronary endothelium damage and cardiomyocyte necrosis but not apoptosis after ischemia and reperfusion: ex-vivo study in rat hearts [0.03%]
维拉帕米在缺血再灌注后可减少大鼠心脏内皮损伤及心肌细胞坏死，但对凋亡无影响：离体实验研究
P. Di Napoli,A. A. Taccardi,A. Grilli et al.
P. Di Napoli et al.
We tested the hypothesis of beneficial effects of the calcium-blocker verapamil in a model of ischemia-reperfusion, and investigated its effects against coronary microcirculation and cardiomyocyte apoptosis. Isolated working rat hearts were...
Fexofenadine in chronic idiopathic urticaria: a clinical and immunohistochemical evaluation [0.03%]
慢性特发性荨麻疹的临床和免疫组化评定研究-西替利嗪与非索非那定的比较
G. A. Vena,N. Cassano,M. Filieri et al.
G. A. Vena et al.
Fexofenadine is a non-sedating selective third-generation antihistamine, which also exerts an anti-inflammatory action. The aim of this study was to evaluate the influence on the expression of inflammatory skin mediators, together with the ...
Effect of yogurt on the inhibition of an intestinal carcinoma by increasing cellular apoptosis [0.03%]
益生菌酸奶通过促进细胞凋亡抑制肠道肿瘤的效果研究
M. M. Rachid,N. M. Gobbato,J. C. Valdéz et al.
M. M. Rachid et al.
Yogurt consumption has been associated with decreased risk of colon cancer. The apoptosis induced by yogurt as a mechanism involved in the inhibition of an experimental intestinal tumor induced by 1,2 dimethylhydrazine (DMH) in BALB/c mice,...
O. Trubiani,S. Guarnieri,R. Paganelli et al.
O. Trubiani et al.
To investigate the in vivo role of caspase-3 in Terminal Transferase metabolism DMSO-treated RPMI-8402, a human pre-T cell line was used. In DMSO treated samples (3)H-dGTP incorporation and TdT phosphorylation occurs after 4 hours of treatm...
N(2)O(2)-induced apoptosis of thymocytes involves mobilization of divalent cations [0.03%]
N(2)O(2)诱导的胸腺细胞凋亡与二价阳离子动员有关
A. Acharya
A. Acharya
More than 90% of thymocytes undergo apoptosis while undergoing differentiation in the thymus. Although several factors act in concert to induce thymocyte apoptosis, it remains speculative if reactive oxygen intermediates produced by thymic ...
Effect of monocyte chemoattractant protein-1 on murine bone marrow cells: proliferation, colony-forming ability and signal transduction pathway involved [0.03%]
单核细胞趋化蛋白-1对小鼠骨髓细胞的作用及信号转导途径的研究
S. K. Biswas,A. Sodhi
S. K. Biswas
Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role in the migration and activation of leukocytes in both physiological and pathological contexts. In this paper, we report the in vitro effect of MCP-1 on myeloid haematopoiesis. ...
G. Riccioni,F. Santilli,N. D&#x;Orazio et al.
G. Riccioni et al.
Cysteinyl leukotrienes (Cys-LTs) are mediators released in asthma and are both direct bronchoconstrictors and proinflammatory substances that mediated several steps in the pathophysiology of chronic asthma, including inflammatory cells recr...
S. Frydas,B. Madhappan,D. Kempuraj
S. Frydas
The objective of these studies is to review the role of some parasites and their components in inflammation, allergy and immune system. We also report recent results published by others group as well as our own.
M. Agostini,B. Di Marco,G. Nocentini et al.
M. Agostini et al.
Antigenic stimuli increase ROS that influence T-cell activation by interfering with the oxidant-antioxidant balance. Oxidative stress takes place when excess of ROS production is not counterbalanced by antioxidant mechanisms and bcl-2 gene ...