Interleukin expression patterns and immune cell infiltration in prostate adenocarcinoma: Implications for recurrence risk [0.03%]
前列腺腺癌中的白细胞介素表达模式和免疫细胞浸润：对复发风险的影响
Jialong Zhang,Cong Huang,Xu Wang et al.
Jialong Zhang et al.
Objective: This study aims to comprehensively investigate the expression profiles of interleukins in prostate adenocarcinoma (PRAD) and their relationship with immune cell infiltration, tumor progression, and patient prog...
Dihydromyricetin improving myocardial function in the mice induced by CCl4 [0.03%]
白鲜素改善四氯化碳诱导的小鼠心肌功能
Wen-Juan Zhang,Ke-Yun Li,Le-Ying Lin et al.
Wen-Juan Zhang et al.
Objective: To study the role and underlying mechanisms of dihydromyricetin on the myocardial function in mice induced by CCl4. Methods: ...
Impact of tacrolimus on interferon gamma ELISpot assay results for the assessment of T-cell immunity: Proof-of-concept [0.03%]
他克莫司对干扰素γELISpot检测结果的影响：评估T细胞免疫的概念性验证
Aurélie Truffot,Jules Weinhard,Pauline Dessaud et al.
Aurélie Truffot et al.
SOT patients require immunosuppressors to avoid graft rejection. Therapeutic drug monitoring is insufficient to find the optimal balance with immunosuppression. The evaluation of cell-mediated immunity by enzyme-linked immunospot (ELISpot) ...
Dissociation between the expression of cGAS/STING and a senescence-associated signature in colon cancer [0.03%]
结肠癌中cGAS/STING的表达与衰老相关特征之间的不关联性
Sofian Al Shboul,Ola Abu Al Karsaneh,Moath Alrjoub et al.
Sofian Al Shboul et al.
Objective: The effect of the cGAS/STING pathway on antitumor immunity and its connection to senescence in vivo necessitates further investigation. Introdu...
Attenuation of senile pruritus by PAC-14028-mediated downregulation of the NF-κB and MAPK pathways [0.03%]
通过PAC-14028介导的NF-κB和MAPK通路下调来减轻老年性瘙痒症
Ji Hye Yoon,Byoung Young Woo,Mi-Yeon Kim et al.
Ji Hye Yoon et al.
Objective: Senile pruritus is a specific type of itching that occurs in elderly persons. Previously, we assessed antagonism of the nonselective ligand-gated cation channel transient receptor potential vanilloid 1 (TRPV1; ...
Administration of anti-GFAP antibodies increases CGRP expression and increases pain hypersensitivity in spinal cord injured animals [0.03%]
抗GFAP抗体的管理增加了脊髓损伤动物中CGRP的表达和疼痛超敏反应
Georgene W Hergenroeder,Samuel T Molina,Juan J Herrera
Georgene W Hergenroeder
Background: Spinal cord injury (SCI) results in a multitude of cellular and pathological changes including neuronal loss, axonal damage, gliosis, and loss of motor and sensory function. In 40%-70% of patients, SCI can als...
Association of HLA-DR, HLA-DQ, and HLA-B alleles with inclusion body myositis risk: A systematic review, a meta-analysis, a meta-regression and a trial sequential analysis [0.03%]
与包涵体肌炎风险相关的HLA-DR、HLA-DQ和HLA-B等位基因：系统评价、荟萃分析、荟萃回归和试验序贯分析
Tarak Dhaouadi,Awatef Riahi,Taïeb Ben Abdallah et al.
Tarak Dhaouadi et al.
Introduction: Although, several studies have assessed the association of HLA Class I and II genes with inclusion body myositis (IBM), results were inconsistent and between-studies heterogeneity needs to be investigated. ...
Therapeutic drug monitoring and immunogenetic factors associated with the use of adalimumab in Crohn's disease patients [0.03%]
使用英夫利昔单抗治疗的克罗恩病患者的治疗药物监测和免疫遗传因素
Livia Moreira Genaro,Juliana Carron,Marina Moreira de Castro et al.
Livia Moreira Genaro et al.
Crohn's disease (CD) involves immune system interactions with intestinal tissue, driven by pro-inflammatory cytokines like Tumor Necrosis Factor (TNF-α). Adalimumab, targeting TNF-α, regulates associated inflammatory responses. Despite be...
Micronutrient deficiencies in patients with celiac disease: A systematic review and meta-analysis [0.03%]
乳糜泻患者中的微量营养素缺乏：系统回顾与荟萃分析
Saad Lamjadli,Ider Oujamaa,Ikram Souli et al.
Saad Lamjadli et al.
This study aimed to characterize micronutrient deficiencies, including iron, ferritin, folic acid, vitamin D, zinc (Zn), vitamin B12, and copper, in patients with celiac disease, and evaluated the effects of these deficiencies on selected h...
Melatonin alleviates oral epithelial cell inflammation via Keap1/Nrf2 signaling [0.03%]
褪黑素通过Keap1/Nrf2信号传导减轻口腔上皮细胞炎症
Nan Zhang,Wenjing Wang,Rongxia Zhang et al.
Nan Zhang et al.
Background: Oral mucosal diseases manifest primarily as inflammatory conditions. These diseases affect approximately half a billion people worldwide. Obje...