Antidiabetic and antioxidant potential of Crocin in high-fat diet plus streptozotocin-induced type-2 diabetic rats [0.03%]
番红花素对高脂饮食加链脲佐菌素诱导的2型糖尿病大鼠的抗糖尿病和抗氧化潜能
Syed Mohammed Basheeruddin Asdaq,Basheerahmed Abdulaziz Mannasaheb,Raha Orfali et al.
Syed Mohammed Basheeruddin Asdaq et al.
Objectives: Crocin, the principal water-soluble active constituent of saffron, possesses numerous pharmacological activities. The present investigation examined the potential antidiabetic and antioxidant characteristics o...
The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report [0.03%]
抑制测定在疑似过敏女性患者中的应用：病例报告(api g 7)
Natalia Ukleja-Sokołowska,Kinga Lis,Małgorzata Graczyk et al.
Natalia Ukleja-Sokołowska et al.
The symptoms of celery allergy are mainly presented as oral allergy symptom, but there are several case reports of patients who experienced anaphylaxis. Defensin (Api g 7), as a novel allergen in celery root, was described in 2022 r. The fe...
Randomized Controlled Trial
International journal of immunopathology and pharmacology. 2024 Jan-Dec:38:3946320231223004. DOI:10.1177/03946320231223004 2024
The hepatotoxicity of γ-radiation synthesized 5-fluorouracil nanogel versus 5-fluorouracil in rats model [0.03%]
γ射线合成的5-氟尿嘧啶纳米凝胶与5-氟尿嘧啶在大鼠模型中的肝毒性比较研究
Wael Em Barakat,Fatma Sm Moawed,Esraa Sa Ahmed et al.
Wael Em Barakat et al.
Introduction: The clinical use of 5-fluorouracil (5-FU), a routinely used chemotherapy medication, has a deleterious impact on the liver. Therefore, it is necessary to find a less harmful alternative to minimize liver dam...
BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells via regulating the lipoxygenase pathway [0.03%]
BML-111通过调控脂氧合酶途径抑制MCF-7细胞的上皮间充质转化和迁移
Fen Xu,Xiaoyan Zhou,Lan Lin et al.
Fen Xu et al.
Introduction: Aberrant epithelial-mesenchymal transition (EMT) and migration frequently occur during tumour progression. BML-111, an analogue of lipoxin A4, has been implicated in inflammation in cancer research. Methods: 3-(4,5-Dimethyl-2-...
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice [0.03%]
sclareol通过抑制核因子-κB / NOD样受体蛋白3介导的炎症和脂质代谢障碍改善糖尿病小鼠的肝脏损伤
Leilei Tang,Xuan Mei,Mengling Ye et al.
Leilei Tang et al.
Objectives: Sclareol (SCL) is a natural diterpene with anti-inflammation and antioxidant properties. This study aimed to assess the hepatoprotective effects of SCL in diabetic mice. Methods: SCL (10 mg/kg) was administered intragastrically ...
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells [0.03%]
癌症易感基因18通过海绵吸附miR-5586-5p正向调节宫颈癌细胞中NUAK家族激酶1的表达以促进迁移和侵袭
Jingrong Wang,Bocheng Zhang,Sha Gong et al.
Jingrong Wang et al.
Introduction: Cervical squamous cell carcinoma (CESC) is the most common gynecological malignancy worldwide. Although the cancer susceptibility 18 (CASC18) gene was involved in the regulation of cancer biology, its specif...
Shu-Yu Wu,Shi-Jye Chu,Shih-En Tang et al.
Shu-Yu Wu et al.
Objective: Evidence suggests that aldehyde dehydrogenase 2 (ALDH2) offers protection against damage caused by oxidative stress in diverse rodent models. Nonetheless, the effect of Alda-1, a compound that activates ALDH2, ...
Protective effect of rivastigmine against lung injury in acute pancreatitis model in rats via Hsp 70/IL6/ NF-κB signaling cascade [0.03%]
石杉碱甲通过Hsp70/IL6/NF-кB信号途径对急性胰腺炎肺损伤的保护作用
Maha Yehia Kamel,Josef Zekry Attia,Sabreen Mahmoud Ahmed et al.
Maha Yehia Kamel et al.
Acute lung injury (ALI) that develops as a result of AP can progress to acute respiratory distress syndrome. Some hypotheses are proposed to explain the pathophysiology of AP and its related pulmonary hazards. This experiment aimed to evalu...
Development and evaluation of a risk score model based on a WNT score gene-associated signature for predicting the clinical outcome and the tumour microenvironment of hepatocellular carcinoma [0.03%]
基于WNT评分基因特征签名的肝细胞癌临床预后及肿瘤微环境风险评分模型的建立与验证
Penghui Li,Xiao Ma,Di Huang et al.
Penghui Li et al.
Background: Hepatocellular carcinoma (HCC) is currently one of the most life-threatening diseases worldwide. However, the factors, genes, and processes involved in the mechanisms of HCC initiation, development, and metastasis remain to be i...
Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathway [0.03%]
二氯化四氰基茋通过Nrf2/HO-1信号转导途径诱导宫颈癌细胞铁死亡
Xiaoning Wei,Qiaoqiao Huang,Jinbing Huang et al.
Xiaoning Wei et al.
Objective: Our research aims to assess the influence of erastin, a ferroptosis-inducing agent, on cervical cancer cells. Introduction: ...