The beneficial effect of probiotics as an adjuvant treatment in childhood drug resistant epilepsy: A prospective pilot study [0.03%]
益生菌作为儿童难治性药物癫痫辅助治疗的有益作用：一项前瞻性试点研究
Ossama Salah El-Sharkawy,Omnia Fathy El-Rashidy,Iman Ali Abdelhamid Elagouza et al.
Ossama Salah El-Sharkawy et al.
Background: One of the most common long-term neurological disorders affecting children is epilepsy. Even with effective antiseizure medications, one-third of epileptic patients develop drug-resistant epilepsy (DRE). Numer...
Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectives [0.03%]
胆碱酯酶、胆碱能疗法和分子对接：重要考虑因素及未来展望
Snežana M Jovičić
Snežana M Jovičić
Enzyme Che plays an essential role in cholinergic and non-cholinergic functions. It is present in the fertilized/unfertilized eggs and sperm of different species. Inclusion criteria for data collection from electronic databases NCBI and Goo...
A gradient model of renal ischemia reperfusion injury to investigate renal interstitial fibrosis [0.03%]
一种肾缺血再灌注损伤的梯度模型用于研究肾间质纤维化
Fan Yang,Baoping Zhu,Elyce Ozols et al.
Fan Yang et al.
Background: The progression from acute kidney injury to chronic kidney disease poses a significant health challenge. Nonetheless, a constraint in existing animal models of renal ischemia/reperfusion (I/R) injury is the necessity for a sever...
Umbelliprenin improved anti-proliferative effects of ionizing radiation on adult T-cell leukemia/lymphoma cells via interaction with CDK6; an in vitro and in silico study [0.03%]
一种名为欧芹预醇的化合物通过与细胞周期蛋白依赖性激酶6相互作用增强电离辐射对成人T细胞白血病/淋巴瘤细胞抗增殖效果的体外和计算机模拟研究
Keyhan Ebrahimi,Ramin Bagheri,Hamid Gholamhosseinian et al.
Keyhan Ebrahimi et al.
Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy with poor survival rates. The efficacy of radiotherapy in ATL needs enhancement with radiosensitizing agents. This study investigated whether umbelliprenin (UMB) could improve...
Ten-day vonoprazan-based versus fourteen-day proton pump inhibitor-based therapy for first-line Helicobacter pylori eradication in China: A meta-analysis of randomized controlled trials [0.03%]
中国首次根除幽门螺杆菌的 vonoprazan 10天方案与质子泵抑制剂14天方案疗效比较：随机对照试验 Meta 分析
Wenwen Gao,Qian Wang,Xiang Zhang et al.
Wenwen Gao et al.
Background: A shorter treatment duration potentially offers the advantage of reducing adverse events (AEs) and enhancing patient compliance for Helicobacter pylori eradication. However, the difference in eradication rates between short-dura...
Anti-astmatic effect of ROCK inhibitor, GSK429286 A, in experimentally induced allergic airway inflammation [0.03%]
ROCK抑制剂GSK429286A对实验性过敏性气道炎症的抗哮喘作用
Eduard Gondáš,Jozef Mažerik,Matúš Dohál et al.
Eduard Gondáš et al.
Background: Allergic asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, inflammation and remodeling. ROCK inhibitors have now been shown to have the potential to alleviate these symptoms...
The global immune-nutrition-inflammation index (GINI) as a robust prognostic factor in glioblastoma patients treated with the standard stupp protocol [0.03%]
免疫营养炎症指数(GINI)作为标准Stupp方案治疗的胶质母细胞瘤患者的预后因素
Erkan Topkan,Nilufer Kilic Durankus,Sukran Senyurek et al.
Erkan Topkan et al.
Background: Systemic inflammation can significantly impact gliomas' onset, progression, and prognosis. Glioblastoma multiforme (GBM) represents the glioma subtype characterized by the most profound inflammatory and immuno...
Syk protein inhibitors treatment for the allergic symptoms associated with hyper immunoglobulin E syndromes: A focused on a computational approach [0.03%]
基于计算方法针对高免疫球蛋白E综合征相关过敏症状的Syk蛋白抑制剂治疗研究
Mariam Mansouri,Ghyzlane ElHaddoumi,Ilham Kandoussi et al.
Mariam Mansouri et al.
Background: Mutations in the Spleen tyrosine kinase (Syk) protein have significant implications for its function and response to treatments. Understanding these mutations and identifying new inhibitors can lead to more effective therapies f...
Implication of IL-12A, IL-12B, IL-6, and TNF single-nucleotide polymorphisms in severity and susceptibility to COVID-19 [0.03%]
IL-12A、IL-12B、IL-6和TNF单核苷酸多态性在COVID-19易感性和严重程度中的作用
R Benmansour,M R Tagajdid,I A Lahlou et al.
R Benmansour et al.
Background: The Coronavirus Disease 2019 (COVID-19) pandemic has led to significant global morbidity and mortality. Understanding the genetic factors that influence disease outcomes can provide critical insights into path...