Gerlinde A S Metz,Jamshid Faraji
Gerlinde A S Metz
Siddhartha Das,Amanda Rundblad,Irene Fontes Marques et al.
Siddhartha Das et al.
Environmental exposures, including air pollutants and lack of natural spaces, are associated with suboptimal health outcomes in children. We aimed to study the associations between environmental exposures and gene expression in children. As...
Intercontinental insights into autism spectrum disorder: a synthesis of environmental influences and DNA methylation [0.03%]
孤独症谱系障碍的跨国界研究综述：环境影响与DNA甲基化的综合分析
George E Kuodza,Ray Kawai,Janine M LaSalle
George E Kuodza
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by a broad range of symptoms. The etiology of ASD is thought to involve complex gene-environment interactions, which are crucial to understanding its vari...
A new approach to study stochastic epigenetic mutations in sperm methylome of Vietnam war veterans directly exposed to Agent Orange [0.03%]
越南战争退伍军人直接接触橙剂的精子甲基化谱随机表观遗传突变的新研究方法
Luigi Corsaro,Davide Sacco,Carlo Corbetta et al.
Luigi Corsaro et al.
Among the various environmental pollutants, dioxin, a highly toxic and widely used compound, is associated with numerous adverse health effects, including a potentially toxic multigenerational effect. Understanding the mechanisms by which d...
Maternal mitochondrial DNA copy number and methylation as possible predictors of pregnancy outcomes in a Michigan pregnancy cohort [0.03%]
Michigan 地区妊娠妇女线粒体DNA拷贝数和甲基化水平与其妊娠结局的关系研究
Maria E Cinzori,Megan Nicol,Alisa L Dewald et al.
Maria E Cinzori et al.
Little is understood about the roles of mitochondria in pregnancy-related adaptations. Therefore, we evaluated associations of maternal early-to-mid pregnancy mitochondrial DNA copy number (mtDNAcn) and mtDNA methylation with birth size and...
Epigenetic biomarker for preeclampsia-associated preterm birth and potential preventative medicine [0.03%]
子痫前期相关性早产的表观遗传生物标志物及潜在预防药物
Eric E Nilsson,Paul Winchester,Cathy Proctor et al.
Eric E Nilsson et al.
Preterm birth (PTB) has dramatically increased within the population (i.e. >10%) and preeclampsia is a significant sub-category of PTB. Currently, there are no practical clinical parameters or biomarkers which predict preeclampsia induced P...
Prenatal exposure to maternal smoking and adult lung cancer risk: a nested case-control study using peripheral blood leukocyte DNA methylation prediction of exposure [0.03%]
基于外周血白细胞DNA甲基化的巢式病例对照研究评估孕期母系吸烟与成年期肺癌风险之间的关系
Meng Ru,Dominique S Michaud,Naisi Zhao et al.
Meng Ru et al.
A prior study reported no association between prenatal smoking methylation scores and adult lung cancer risk adjusting for methylation-predicted adult smoking, without considering maternal smoking trends by birth cohort. To address this gap...
DNA methylation correlates with transcriptional noise in response to elevated pCO2 in the eastern oyster (Crassostrea virginica) [0.03%]
DNA甲基化与东部牡蛎(Crassostrea virginica)对高二氧化碳环境转录噪音的相关性研究
Yaamini R Venkataraman,Ariana S Huffmyer,Samuel J White et al.
Yaamini R Venkataraman et al.
Ocean acidification significantly affects marine calcifiers like oysters, warranting the study of molecular mechanisms like DNA methylation that contribute to adaptive plasticity in response to environmental change. However, a consensus has...
EV-miRNA associated with environmental air pollution exposures in the MADRES cohort [0.03%]
MADRES队列中与环境空气污染暴露相关的EV-miRNA
Helen Bermudez Foley,Sandrah P Eckel,Tingyu Yang et al.
Helen Bermudez Foley et al.
Air pollution is a hazardous contaminant, exposure to which has substantial consequences for health during critical periods, such as pregnancy. MicroRNA (miRNA) is an epigenetic mechanism that modulates transcriptome responses to the enviro...
DNA methylation is associated with hair trace elements in female adolescents from two vulnerable populations in the Colombian Caribbean [0.03%]
哥伦比亚加勒比地区两个易受损害人群中女性青少年头发中的微量元素与DNA甲基化有关
Alejandra Manjarres-Suarez,Anne Bozack,Andres Cardenas et al.
Alejandra Manjarres-Suarez et al.
Exposure to trace elements (TEs) influences DNA methylation patterns, which may be associated with disease development. Vulnerable populations, such as adolescents undergoing maturity, are susceptible to the effects of TE exposure. The aim ...