Deciphering differences in DNA methylation and transcriptome profiles of oocytes from pigs with high and low developmental competence [0.03%]
高效和低效卵母细胞DNA甲基化及转录组谱系的解读
Laura Abril-Parreño,Jordana S Lopes,Jon Romero-Aguirregomezcorta et al.
Laura Abril-Parreño et al.
In vitro maturation (IVM) is a critical step in animal in vitro embryo production, yet oocytes matured in vitro often exhibit lower developmental competence than their in vivo counterparts. However, the molecular mechanisms behind this obse...
Mapping heat stress-induced core histone post-translational modifications in Acropora cervicornis [0.03%]
Acropora cervicornis热应力诱导的核小体组蛋白修饰映射研究
Cassandra N Fuller,Sabrina Mansoor,Santiago J Guzman et al.
Cassandra N Fuller et al.
Histone post-translational modifications (PTMs) participate in the dynamic regulation of chromatin structure and function, through their chemical nature and specific location within the histone sequence. Alternative analytical approaches fo...
Multigenerational inheritance of parasitic stress memory in Drosophila melanogaster [0.03%]
果蝇中寄生压力记忆的跨世代继承
Shagufta Khan,Ravina Saini,Runa Hamid et al.
Shagufta Khan et al.
Organisms detect harmful environmental conditions and employ strategies to protect themselves. Additionally, they can communicate these experiences to the next generation or beyond through non-DNA sequence-based mechanisms, known as interge...
Elia Mario Biganzoli,Valentina Bollati
Elia Mario Biganzoli
Traditionally viewed as a set of switches regulating gene expression, epigenetic mechanisms may also operate as an information-processing system with symbolic and subsymbolic features. In this framework, gene-specific DNA methylation and ot...
Global maintenance of histone post-translational modifications during the transition into anoxia in embryos of the annual killifish Austrofundulus limnaeus [0.03%]
秘鳉(Austrofundulus limnaeus)胚胎在无氧过渡期间组蛋白翻译后修饰的全球维持机制研究
Chelsea Hughes,Elizabeth A Mojica,Dietmar Kültz et al.
Chelsea Hughes et al.
Many organisms have adapted to survive anoxic or hypoxic environments, but the epigenetic responses involved in this successful stress response are not well described in most species. Embryos of the annual killifish Austrofundulus limnaeus ...
Immediate and durable effects of maternal tobacco consumption on placental DNA methylation: a replication and discovery study [0.03%]
母亲烟草暴露对胎盘DNA甲基化的影响：一项验证和发现研究
Chloé Masdoumier,Lucile Broséus,Florent Chuffart et al.
Chloé Masdoumier et al.
An increasing number of epigenome-wide association studies report tobacco smoking-associated DNA methylation levels. However, comprehensive replication studies remain scarce, particularly in placenta, despite their crucial interest in such ...
Exposure to fine particulate matter in adults is associated with immune cell gene expression related to inflammation, the electron transport chain, and cell cycle regulation [0.03%]
成人接触细颗粒物与免疫细胞表达有关炎症、电子传递链和细胞周期调节的基因密切相关
Amanda Rundblad,Siddhartha Das,Bigina N R Ginos et al.
Amanda Rundblad et al.
Exposure to air pollution and an unhealthy built environment increase disease risk by impacting metabolic risk factors and inflammation, potentially via epigenetic modifications and effects on gene expression. We aimed to explore associatio...
Molecular responses of chicken embryos to maternal heat stress through DNA methylation and gene expression: a pilot study [0.03%]
母体热应激通过DNA甲基化和基因表达对鸡胚的分子响应：初步研究
Keyvan Karami,Jules Sabban,Chloé Cerutti et al.
Keyvan Karami et al.
Climate change, with its repercussions on agriculture, is one of the most important adaptation challenges for livestock production. Poultry production is a major source of proteins for human consumption all over the world. With a growing hu...
Prenatal ambient air pollution associations with DNA methylation in asthma- and allergy-relevant genes: findings from ECHO [0.03%]
孕期环境空气污染与哮喘和过敏相关基因DNA甲基化的关系：ECHO项目结果
Meredith Palmore,Emma E Thompson,Fang Fang et al.
Meredith Palmore et al.
Prenatal exposure to air pollution is an important risk factor for child health outcomes, including asthma. Identification of DNA methylation changes associated with air pollutant exposure can provide new intervention targets to improve chi...
Extended abstinence from morphine alters sperm smRNA expression and prevents transmission of intergenerational phenotypes [0.03%]
吗啡断瘾可改变精子smRNA表达并阻止跨代表型传递
Dana Zeid,Andre B Toussaint,Carmen Dressler et al.
Dana Zeid et al.
Paternal exposure to drugs of abuse can impact addiction-related behaviours in progeny via germline epigenome remodelling. Previously, we found that offspring of morphine-exposed male rats showed increased morphine-taking, diminished adoles...