A cross-study analysis of prenatal exposures to environmental contaminants and the epigenome: support for stress-responsive transcription factor occupancy as a mediator of gene-specific CpG methylation patterning [0.03%]
环境污染物的孕期暴露与表观基因的研究：支持转录因子结合作为特定基因CpG甲基化模式的中介因素
Elizabeth M Martin,Rebecca C Fry
Elizabeth M Martin
A biological mechanism by which exposure to environmental contaminants results in gene-specific CpG methylation patterning is currently unknown. We hypothesize that gene-specific CpG methylation is related to environmentally perturbed trans...
PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes [0.03%]
PON1：遗传、表观遗传及表达数据的候选易感基因整合模型
Karen Huen,Paul Yousefi,Kelly Street et al.
Karen Huen et al.
Recent genome- and epigenome-wide studies demonstrate that the DNA methylation is controlled in part by genetics, highlighting the importance of integrating genetic and epigenetic data. To better understand molecular mechanisms affecting ge...
Epigenetics-a potential mediator between air pollution and preterm birth [0.03%]
表观遗传学-空气污染与早产之间的潜在介质
Vania W Lin,Andrea A Baccarelli,Heather H Burris
Vania W Lin
Preterm birth is a major cause of infant morbidity and mortality and a potential risk factor for adult chronic disease. With over 15 million infants born preterm worldwide each year, preterm birth poses a global health concern. There is a p...