Michael K Skinner
Michael K Skinner
Epigenetic clocks and research implications of the lack of data on whom they have been developed: a review of reported and missing sociodemographic characteristics [0.03%]
表观遗传时钟及其研究中缺乏数据的影响：已报告和缺失的人口社会特征综述
Sarah Holmes Watkins,Christian Testa,Jarvis T Chen et al.
Sarah Holmes Watkins et al.
Epigenetic clocks are increasingly being used as a tool to assess the impact of a wide variety of phenotypes and exposures on healthy ageing, with a recent focus on social determinants of health. However, little attention has been paid to t...
Transgenerational sperm DMRs escape DNA methylation erasure during embryonic development and epigenetic inheritance [0.03%]
跨越世代的精子DMRs在胚胎发育过程中逃逸DNA甲基化擦除并进行表观遗传学传递
Millissia Ben Maamar,Yue Wang,Eric E Nilsson et al.
Millissia Ben Maamar et al.
Germline transmission of epigenetic information is a critical component of epigenetic inheritance. Previous studies have suggested that an erasure of DNA methylation is required to develop stem cells in the morula embryo. An exception invol...
Geetha Venkatesh,Sina Tönges,Katharina Hanna et al.
Geetha Venkatesh et al.
DNA methylation is an important epigenetic modification that is widely conserved across animal genomes. It is widely accepted that DNA methylation patterns can change in a context-dependent manner, including in response to changing environm...
Transgenerational epigenetic inheritance of axonal regeneration after spinal cord injury [0.03%]
脊髓损伤后轴突再生的跨代表观遗传学继承现象
Andy Madrid,Reid S Alisch,Elias Rizk et al.
Andy Madrid et al.
Human epidemiological studies reveal that dietary and environmental alterations influence the health of the offspring and that the effect is not limited to the F1 or F2 generations. Non-Mendelian transgenerational inheritance of traits in r...
Hexavalent chromium-induced epigenetic instability and transposon activation lead to phenotypic variations and tumors in Drosophila [0.03%]
六价铬通过表观遗传不稳定和转座子激活导致果蝇发生表型变异和肿瘤
Rasesh Y Parikh,Vamsi K Gangaraju
Rasesh Y Parikh
Developmental robustness represents the ability of an organism to resist phenotypic variations despite environmental insults and inherent genetic variations. Derailment of developmental robustness leads to phenotypic variations that can get...
Effects of paternal methionine supplementation on sperm DNA methylation and embryo transcriptome in sheep [0.03%]
公羊甲硫氨酸补充对精子dna甲基化和胚胎转录组的影响
Jessica Townsend,Camila U Braz,Todd Taylor et al.
Jessica Townsend et al.
Environmental effects on gene expression and offspring development can be mediated by epigenetic modifications. It is well established that maternal diet influences DNA methylation patterns and phenotypes in the offspring; however, the epig...
Duration of exposure to epidural anesthesia at delivery, DNA methylation in umbilical cord blood and their association with offspring asthma in Non-Hispanic Black women [0.03%]
硬膜外麻醉暴露时间，脐带血DNA甲基化及其与非西班牙裔黑人女性后代哮喘的关联研究
Yaxu Wang,Jung-Ying Tzeng,Yueyang Huang et al.
Yaxu Wang et al.
Epidural anesthesia is an effective pain relief modality, widely used for labor analgesia. Childhood asthma is one of the commonest chronic medical illnesses in the USA which places a significant burden on the health-care system. We recentl...
Meghna Rajaprakash,Lorraine T Dean,Meredith Palmore et al.
Meghna Rajaprakash et al.
This review article provides a framework for the use of deoxyribonucleic acid (DNA) methylation (DNAm) biomarkers to study the biological embedding of socioeconomic position (SEP) and summarizes the latest developments in the area. It prese...
Michael K Skinner
Michael K Skinner