Tory A Hendry,Kelley A Gallagher
Tory A Hendry
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation [0.03%]
类真核细胞的gephyrin及相应的膜受体协调分枝杆菌细胞分裂和极性伸长
Mariano Martinez,Julienne Petit,Alejandro Leyva et al.
Mariano Martinez et al.
The order Corynebacteriales includes major industrial and pathogenic Actinobacteria such as Corynebacterium glutamicum or Mycobacterium tuberculosis. These bacteria have multi-layered cell walls composed of the mycolyl-arabinogalactan-pepti...
Genome content predicts the carbon catabolic preferences of heterotrophic bacteria [0.03%]
基因组含量可预测异养菌的碳代谢偏好性
Matti Gralka,Shaul Pollak,Otto X Cordero
Matti Gralka
Heterotrophic bacteria-bacteria that utilize organic carbon sources-are taxonomically and functionally diverse across environments. It is challenging to map metabolic interactions and niches within microbial communities due to the large num...
Bacterial c-di-GMP has a key role in establishing host-microbe symbiosis [0.03%]
细菌c-di-GMP在宿主微生物共生关系建立中起关键作用
Nancy Obeng,Anna Czerwinski,Daniel Schütz et al.
Nancy Obeng et al.
Most microbes evolve faster than their hosts and should therefore drive evolution of host-microbe interactions. However, relatively little is known about the characteristics that define the adaptive path of microbes to host association. Her...
Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection [0.03%]
单细胞大规模平行多重微生物测序（M3-seq）可识别稀有细菌种群并分析噬菌体感染状况
Bruce Wang,Aaron E Lin,Jiayi Yuan et al.
Bruce Wang et al.
Bacterial populations are highly adaptive. They can respond to stress and survive in shifting environments. How the behaviours of individual bacteria vary during stress, however, is poorly understood. To identify and characterize rare bacte...
Kevin Ciminski,Geoffrey Chase,Martin Schwemmle et al.
Kevin Ciminski et al.
Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates [0.03%]
具有治疗作用的噬菌体BPs和Muddy需要海藻糖聚酚酸
Katherine S Wetzel,Morgane Illouz,Lawrence Abad et al.
Katherine S Wetzel et al.
Mycobacteriophages show promise as therapeutic agents for non-tuberculous mycobacterium infections. However, little is known about phage recognition of Mycobacterium cell surfaces or mechanisms of phage resistance. We show here that trehalo...
Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella [0.03%]
帕金森病相关激酶LRRK2调控细胞自有的佛尔蒙酸依赖的抗菌防御途径以应对胞内沙门氏菌感染
Huan Lian,Donghyun Park,Meixin Chen et al.
Huan Lian et al.
Cell-intrinsic defences constitute the first line of defence against intracellular pathogens. The guanosine triphosphatase RAB32 orchestrates one such defence response against the bacterial pathogen Salmonella, through delivery of antimicro...
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia [0.03%]
对埃塞俄比亚抗疟诊断药物青蒿素的抗药性问题不容忽视
Abebe A Fola,Sindew M Feleke,Hussein Mohammed et al.
Abebe A Fola et al.
Diagnosis and treatment of Plasmodium falciparum infections are required for effective malaria control and are pre-requisites for malaria elimination efforts; hence we need to monitor emergence, evolution and spread of drug- and diagnostics...