The niche-specialist and age-related oral microbial ecosystem: crosstalk with host immune cells in homeostasis [0.03%]
小众专长和年龄相关的口腔微生物生态系统：稳态下与宿主免疫细胞的相互作用
Dongjia Lin,Qiannan Hu,Lisa Yang et al.
Dongjia Lin et al.
Although characterization of the baseline oral microbiota has been discussed, the current literature seems insufficient to draw a definitive conclusion on the interactions between the microbes themselves or with the host. This study focuses...
Whole-genome sequencing enhances existing pathogen and antimicrobial-resistance surveillance schemes within a neonatal unit [0.03%]
全基因组测序可增强新生儿病室现有致病菌和抗菌药物耐药性监测方案
Vivien Price,Steven J Dunn,Robert A Moran et al.
Vivien Price et al.
In some neonatal units, the screening of isolates for antimicrobial-resistant organisms is a matter of routine, with theoretical benefits including the prevention or early detection of outbreaks. This study sought to use whole-genome sequen...
Insights into plastic biodegradation: community composition and functional capabilities of the superworm (Zophobas morio) microbiome in styrofoam feeding trials [0.03%]
超 worm(Zophobas morio)微生物组在泡沫聚苯乙烯取食实验中的组成和功能能力分析
Jiarui Sun,Apoorva Prabhu,Samuel T N Aroney et al.
Jiarui Sun et al.
Plastics are inexpensive and widely used organic polymers, but their high durability hinders biodegradation. Polystyrene, including extruded polystyrene (also known as styrofoam), is among the most commonly produced plastics worldwide and i...
Local accessory gene sharing among Egyptian Campylobacter potentially promotes the spread of antimicrobial resistance [0.03%]
埃及弯曲杆菌属细菌的局部配体基因共享或可促进抗生素抗性传播
Shaimaa F Mouftah,Ben Pascoe,Jessica K Calland et al.
Shaimaa F Mouftah et al.
Campylobacter is the most common cause of bacterial gastroenteritis worldwide, and diarrhoeal disease is a major cause of child morbidity, growth faltering and mortality in low- and middle-income countries. Despite evidence of high inciden...
Curation of the AMRFinderPlus databases: applications, functionality and impact [0.03%]
AMRFinderPlus数据库的整理：应用、功能及影响
Michael Feldgarden,Vyacheslav Brover,Boris Fedorov et al.
Michael Feldgarden et al.
Antimicrobial resistance (AMR) is a significant public health threat. Low-cost whole-genome sequencing, which is often used in surveillance programmes, provides an opportunity to assess AMR gene content in these genomes using in silico appr...
The characterization of Moraxella catarrhalis carried in the general population [0.03%]
人群中摩拉克菌的定植特征研究
Denise E Morris,Karen L Osman,David W Cleary et al.
Denise E Morris et al.
Moraxella catarrhalis is a common cause of respiratory tract infection, particularly otitis media in children, whilst it is also associated with the onset of exacerbation in chronic obstructive pulmonary disease in adults. Despite the need ...
Target-enrichment sequencing yields valuable genomic data for challenging-to-culture bacteria of public health importance [0.03%]
靶向富集测序技术揭示重要难培养病原菌的基因组信息
Tristan P W Dennis,Barbara K Mable,Brian Brunelle et al.
Tristan P W Dennis et al.
Genomic data contribute invaluable information to the epidemiological investigation of pathogens of public health importance. However, whole-genome sequencing (WGS) of bacteria typically relies on culture, which represents a major hurdle fo...
Genomic epidemiology and temperature dependency of hypermucoviscous Klebsiella pneumoniae in Japan [0.03%]
日本的基因组流行病学和高温依赖性高粘性的肺炎克雷伯菌
Mi Nguyen-Tra Le,Shizuo Kayama,Kelly L Wyres et al.
Mi Nguyen-Tra Le et al.
Klebsiella pneumoniae (Kp) has emerged as a global life-threatening pathogen owing to its multidrug resistance and hypervirulence phenotype. Several fatal outbreaks of carbapenem-resistant hypervirulent Kp have been reported recently. Hyper...
RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12 [0.03%]
regulonDB 11.0：大肠杆菌 K-12 转录调控的综合大规模数据集
Víctor H Tierrafría,Claire Rioualen,Heladia Salgado et al.
Víctor H Tierrafría et al.
Genomics has set the basis for a variety of methodologies that produce high-throughput datasets identifying the different players that define gene regulation, particularly regulation of transcription initiation and operon organization. Thes...
Enabling genomic island prediction and comparison in multiple genomes to investigate bacterial evolution and outbreaks [0.03%]
启动基因组岛预测和比较以调查细菌进化和疫情
Claire Bertelli,Kristen L Gray,Nolan Woods et al.
Claire Bertelli et al.
Outbreaks of virulent and/or drug-resistant bacteria have a significant impact on human health and major economic consequences. Genomic islands (GIs; defined as clusters of genes of probable horizontal origin) are of high interest because t...