Genomic dissection of the Vibrio cholerae O-serogroup global reference strains: reassessing our view of diversity and plasticity between two chromosomes [0.03%]
弧菌基因组的染色体多样性及可塑性的全球参考菌株分析：重新评估两套染色体之间的差异性及可塑性
Kazunori Murase,Eiji Arakawa,Hidemasa Izumiya et al.
Kazunori Murase et al.
Approximately 200 O-serogroups of Vibrio cholerae have already been identified; however, only 2 serogroups, O1 and O139, are strongly related to pandemic cholera. The study of non-O1 and non-O139 strains has hitherto been limited. Neverthel...
Insertion sequences and other mobile elements associated with antibiotic resistance genes in Enterococcus isolates from an inpatient with prolonged bacteraemia [0.03%]
耐药基因相关的插入序列和其他可移动元件在一位长期菌血病住院患者肠球菌分离株中的关联性研究
Zulema Udaondo,Kaleb Z Abram,Atul Kothari et al.
Zulema Udaondo et al.
Insertion sequences (ISs) and other transposable elements are associated with the mobilization of antibiotic resistance determinants and the modulation of pathogenic characteristics. In this work, we aimed to investigate the association bet...
Alexander Dietrich,Monica Steffi Matchado,Maximilian Zwiebel et al.
Alexander Dietrich et al.
16S rRNA gene profiling is currently the most widely used technique in microbiome research and allows the study of microbial diversity, taxonomic profiling, phylogenetics, functional and network analysis. While a plethora of tools have been...
Kayla N Conner,Joseph T Burke,Janani Ravi et al.
Kayla N Conner et al.
Listeria monocytogenes (Lm) is a bacterial pathogen that causes listeriosis in immunocompromised individuals, particularly pregnant women. Several virulence factors support the intracellular lifecycle of Lm and facilitate cell-to-cell sprea...
Genome-resolved metagenomics reveals novel archaeal and bacterial genomes from Amazonian forest and pasture soils [0.03%]
基于基因组的宏基因组揭示了亚马逊森林和牧场土壤中新型古菌和细菌基因组
Andressa M Venturini,Júlia B Gontijo,Jéssica A Mandro et al.
Andressa M Venturini et al.
Amazonian soil microbial communities are known to be affected by the forest-to-pasture conversion, but the identity and metabolic potential of most of their organisms remain poorly characterized. To contribute to the understanding of these ...
Replacement of the Alpha variant of SARS-CoV-2 by the Delta variant in Lebanon between April and June 2021 [0.03%]
2021年4月至6月黎巴嫩新冠病毒Alpha变异株被Delta变异株替代
Georgi Merhi,Alexander J Trotter,Leonardo de Oliveira Martins et al.
Georgi Merhi et al.
The COVID-19 pandemic continues to expand globally, with case numbers rising in many areas of the world, including the Eastern Mediterranean Region. Lebanon experienced its largest wave of COVID-19 infections from January to April 2021. Lim...
Corrigendum: Genome plasticity driven by aneuploidy and loss of heterozygosity in Trypanosoma cruzi [0.03%]
致歉：染色体非整倍体和等位基因杂合性损失驱动的克氏锥虫基因组可塑性纠正说明
Lissa Cruz-Saavedra,Philipp Schwabl,Gustavo A Vallejo et al.
Lissa Cruz-Saavedra et al.
Magdalena Ksiezarek,Filipa Grosso,Teresa Gonçalves Ribeiro et al.
Magdalena Ksiezarek et al.
The genus Limosilactobacillus (formerly Lactobacillus ) contains multiple species considered to be adapted to vertebrates, yet their genomic diversity has not been explored. In this study, we performed comparative genomic analysis of Li...
Distinct Streptococcus pneumoniae cause invasive disease in Papua New Guinea [0.03%]
不同的肺炎链球菌在巴布亚新几内亚导致侵袭性疾病
Kate C Mellor,Stephanie Lo,Mition Yoannes et al.
Kate C Mellor et al.
Streptococcus pneumoniae is a key contributor to childhood morbidity and mortality in Papua New Guinea (PNG). For the first time, whole genome sequencing of 174 isolates has enabled detailed characterisation of diverse S. pneumoniae causing...
Fine-grain population structure and transmission patterns of Mycobacterium tuberculosis in southern Mozambique, a high TB/HIV burden area [0.03%]
莫桑比克南部地区细粒度人口结构及结核分枝杆菌传播模式调查研究（高结核/艾滋负担区域）
Belén Saavedra Cervera,Mariana G López,Álvaro Chiner-Oms et al.
Belén Saavedra Cervera et al.
Genomic studies of the Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. To...