Making microbial genomics work for clinical and public health microbiology [0.03%]
让微生物基因组学在临床和公共卫生微生物学中发挥作用
Taj Azarian,Norelle L Sherry,Kate Baker et al.
Taj Azarian et al.
Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011-2018 determined through whole-genome sequencing [0.03%]
俄罗斯中部和西北部2011-2018年通过全基因组测序获得的肺炎链球菌分离株的特点分析
Ekaterina Egorova,Narender Kumar,Rebecca A Gladstone et al.
Ekaterina Egorova et al.
Invasive pneumococcal disease remains one of the leading causes of morbidity and mortality worldwide. In Russia, 13- valent pneumococcal conjugate vaccine (PCV13) was introduced into the childhood immunization programme nationwide in 2014. ...
Phylogenomic analysis of the genus Delftia reveals distinct major lineages with ecological specializations [0.03%]
全基因组系统发生分析揭示了具有生态特化的泛菌属的主要谱系
Supriya V Bhat,Heather Maughan,Andrew D S Cameron et al.
Supriya V Bhat et al.
Delftia is a diverse betaproteobacterial genus with many strains having agricultural and industrial relevance, including plant-growth promotion, bioremediation of hydrocarbon-contaminated soils, and heavy metal immobilization. Delftia spp. ...
Changes to the upper gastrointestinal microbiotas of children with reflux oesophagitis and oesophageal metaplasia [0.03%]
儿童胃食管反流病和食管鳞状异形增生的上消化道微生物群变化
Laurence D W Luu,Harveen Singh,Natalia Castaño-Rodríguez et al.
Laurence D W Luu et al.
Little is known of the relationships among paediatric upper gastrointestinal microbiotas, and the impact of medication use and disease on their diversity. Here, we investigated the diversity of three microbiotas in the upper gastrointestina...
Phylodynamic analysis of SARS-CoV-2 spread in Rio de Janeiro, Brazil, highlights how metropolitan areas act as dispersal hubs for new variants [0.03%]
里约热内卢的SARS-CoV-2传播的谱系动态分析强调了大都市地区作为新的病毒变种扩散中心的作用
Alessandra Pavan Lamarca,Luiz G P de Almeida,Ronaldo da Silva Francisco et al.
Alessandra Pavan Lamarca et al.
During the first semester of 2021, all of Brazil has suffered an intense wave of COVID-19 associated with the Gamma variant. In July, the first cases of Delta variant were detected in the state of Rio de Janeiro. In this work, we have emplo...
Ribosomal MLST nucleotide identity (rMLST-NI), a rapid bacterial species identification method: application to Klebsiella and Raoultella genomic species validation [0.03%]
基于核糖体的多位点序列打分法（rMLST-NI）：一种快速细菌物种鉴定方法及其在肺炎克雷伯菌和臭鼻克雷伯菌基因种分类验证中的应用
James E Bray,Annapaula Correia,Margaret Varga et al.
James E Bray et al.
Bacterial genomics is making an increasing contribution to the fields of medicine and public health microbiology. Consequently, accurate species identification of bacterial genomes is an important task, particularly as the number of genomes...
Desulfuromonas sp. 'CSMB_57', isolation and genomic insights from the most abundant bacterial taxon in eastern Australian coals [0.03%]
澳大利亚东部煤中的优势细菌种群脱硫单胞菌的分离及基因组分析
Andrew G McLeish,Paul Greenfield,David J Midgley et al.
Andrew G McLeish et al.
One of the most abundant and ubiquitous taxa observed in eastern Australian coal seams is an uncultured Desulfuromonas species and part of the Coal Seam Microbiome dataset assigned as 'CSMB_57'. Despite this abundance and ubiquity, knowledg...
Contrasting long-term dynamics of antimicrobial resistance and virulence plasmids in Salmonella Typhimurium from animals [0.03%]
动物来源的伤寒沙门氏菌抗菌药物抗性可移动遗传元件和毒力质粒的长期动态变化趋势差异分析
Kate C Mellor,Grace A Blackwell,Shaun A Cawthraw et al.
Kate C Mellor et al.
Plasmids are mobile elements that can carry genes encoding traits of clinical concern, including antimicrobial resistance (AMR) and virulence. Population-level studies of Enterobacterales, including Escherichia coli, Shigella and Klebsiella...
Shooting hoops: globetrotting plasmids spreading more than just antimicrobial resistance genes across One Health [0.03%]
穿梭于医、兽、环三界中的质粒：不仅传播抗性基因而且促进耐药性的产生与演化
Cian Smyth,Robert J Leigh,Sarah Delaney et al.
Cian Smyth et al.
Our study provides novel insights into the global nature of antimicrobial resistance (AMR) plasmids across the food chain. We provide compelling evidence of the globetrotting nature of AMR plasmids and the need for surveillance to sequence ...
Homologous recombination between tandem paralogues drives evolution of a subset of type VII secretion system immunity genes in firmicute bacteria [0.03%]
革兰氏阳性菌中并列同源重组驱动的一类VII型分泌系统免疫基因的进化
Stephen R Garrett,Giuseppina Mariano,Jo Dicks et al.
Stephen R Garrett et al.
The type VII secretion system (T7SS) is found in many Gram-positive firmicutes and secretes protein toxins that mediate bacterial antagonism. Two T7SS toxins have been identified in Staphylococcus aureus, EsaD a nuclease toxin that is count...