Local accessory gene sharing among Egyptian Campylobacter potentially promotes the spread of antimicrobial resistance [0.03%]
埃及弯曲杆菌属细菌的局部配体基因共享或可促进抗生素抗性传播
Shaimaa F Mouftah,Ben Pascoe,Jessica K Calland et al.
Shaimaa F Mouftah et al.
Campylobacter is the most common cause of bacterial gastroenteritis worldwide, and diarrhoeal disease is a major cause of child morbidity, growth faltering and mortality in low- and middle-income countries. Despite evidence of high inciden...
Curation of the AMRFinderPlus databases: applications, functionality and impact [0.03%]
AMRFinderPlus数据库的整理：应用、功能及影响
Michael Feldgarden,Vyacheslav Brover,Boris Fedorov et al.
Michael Feldgarden et al.
Antimicrobial resistance (AMR) is a significant public health threat. Low-cost whole-genome sequencing, which is often used in surveillance programmes, provides an opportunity to assess AMR gene content in these genomes using in silico appr...
The characterization of Moraxella catarrhalis carried in the general population [0.03%]
人群中摩拉克菌的定植特征研究
Denise E Morris,Karen L Osman,David W Cleary et al.
Denise E Morris et al.
Moraxella catarrhalis is a common cause of respiratory tract infection, particularly otitis media in children, whilst it is also associated with the onset of exacerbation in chronic obstructive pulmonary disease in adults. Despite the need ...
Target-enrichment sequencing yields valuable genomic data for challenging-to-culture bacteria of public health importance [0.03%]
靶向富集测序技术揭示重要难培养病原菌的基因组信息
Tristan P W Dennis,Barbara K Mable,Brian Brunelle et al.
Tristan P W Dennis et al.
Genomic data contribute invaluable information to the epidemiological investigation of pathogens of public health importance. However, whole-genome sequencing (WGS) of bacteria typically relies on culture, which represents a major hurdle fo...
Genomic epidemiology and temperature dependency of hypermucoviscous Klebsiella pneumoniae in Japan [0.03%]
日本的基因组流行病学和高温依赖性高粘性的肺炎克雷伯菌
Mi Nguyen-Tra Le,Shizuo Kayama,Kelly L Wyres et al.
Mi Nguyen-Tra Le et al.
Klebsiella pneumoniae (Kp) has emerged as a global life-threatening pathogen owing to its multidrug resistance and hypervirulence phenotype. Several fatal outbreaks of carbapenem-resistant hypervirulent Kp have been reported recently. Hyper...
RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12 [0.03%]
regulonDB 11.0：大肠杆菌 K-12 转录调控的综合大规模数据集
Víctor H Tierrafría,Claire Rioualen,Heladia Salgado et al.
Víctor H Tierrafría et al.
Genomics has set the basis for a variety of methodologies that produce high-throughput datasets identifying the different players that define gene regulation, particularly regulation of transcription initiation and operon organization. Thes...
Enabling genomic island prediction and comparison in multiple genomes to investigate bacterial evolution and outbreaks [0.03%]
启动基因组岛预测和比较以调查细菌进化和疫情
Claire Bertelli,Kristen L Gray,Nolan Woods et al.
Claire Bertelli et al.
Outbreaks of virulent and/or drug-resistant bacteria have a significant impact on human health and major economic consequences. Genomic islands (GIs; defined as clusters of genes of probable horizontal origin) are of high interest because t...
Investigating plant disease outbreaks with long-read metagenomics: sensitive detection and highly resolved phylogenetic reconstruction applied to Xylella fastidiosa [0.03%]
基于长读长宏基因组学调查植物病害爆发：弗式非洲氯叶斑病菌的敏感检测和高分辨率系统发育重建研究
Marcela A Johnson,Haijie Liu,Elizabeth Bush et al.
Marcela A Johnson et al.
Early disease detection is a prerequisite for enacting effective interventions for disease control. Strains of the bacterial plant pathogen Xylella fastidiosa have recurrently spread to new crops in new countries causing devastating outbrea...
Impacts of Mycoplasma agalactiae restriction-modification systems on pan-epigenome dynamics and genome plasticity [0.03%]
Mycoplasma agalactiae限制修饰系统对泛表观基因组动力学和基因组可塑性的影响
Emilie Dordet-Frisoni,Céline Vandecasteele,Rachel Contarin et al.
Emilie Dordet-Frisoni et al.
DNA methylations play an important role in the biology of bacteria. Often associated with restriction modification (RM) systems, they are important drivers of bacterial evolution interfering in horizontal gene transfer events by providing a...
Carriage prevalence and genomic epidemiology of Staphylococcus aureus among Native American children and adults in the Southwestern USA [0.03%]
美国西南部原住民儿童和成人中的金黄色葡萄球菌带菌流行率及基因组流行病学研究
Eleonora Cella,Catherine G Sutcliffe,Carol Tso et al.
Eleonora Cella et al.
Native American individuals in the Southwestern USA experience a higher burden of invasive Staphylococcus aureus disease than the general population. However, little is known about S. aureus carriage in these communities. A cross-sectional ...