A critical evaluation of Mycobacterium bovis pangenomics, with reference to its utility in outbreak investigation [0.03%]
结核分枝杆菌泛基因组的批判性评价及其在疫情调查中的应用价值探讨
Kristina M Ceres,Michael J Stanhope,Yrjö T Gröhn
Kristina M Ceres
The increased accessibility of next generation sequencing has allowed enough genomes from a given bacterial species to be sequenced to describe the distribution of genes in the pangenome, without limiting analyses to genes present in refere...
Genetic background of Cambodian pneumococcal carriage isolates following pneumococcal conjugate vaccine 13 [0.03%]
肺炎结合疫苗13接种后柬埔寨肺炎链球菌携带株的基因背景分析
Sophie Belman,Sona Soeng,Chansovannara Soputhy et al.
Sophie Belman et al.
Streptococcus pneumoniae (the pneumococcus) is a leading cause of childhood mortality globally and in Cambodia. It is commensal in the human nasopharynx, occasionally resulting in invasive disease. Monitoring population genetic shifts, char...
Virulence plasmid pINV as a genetic signature for Shigella flexneri phylogeny [0.03%]
毒力质粒pINV作为志贺菌进化基因标志的证据
Giulia Pilla,Gabriele Arcari,Christoph M Tang et al.
Giulia Pilla et al.
Shigella flexneri is a major health burden in low- and middle-income countries, where it is a leading cause of mortality associated with diarrhoea in children, and shows an increasing incidence among travellers and men having sex with men. ...
Genome plasticity driven by aneuploidy and loss of heterozygosity in Trypanosoma cruzi [0.03%]
由染色体非整倍体和杂合性丧失驱动的克鲁兹锥虫基因组可塑性
Lissa Cruz-Saavedra,Philipp Schwabl,Gustavo A Vallejo et al.
Lissa Cruz-Saavedra et al.
Trypanosoma cruzi the causative agent of Chagas disease shows a marked genetic diversity and divided into at least six Discrete Typing Units (DTUs). High intra genetic variability has been observed in the TcI DTU, the most widely distribute...
Population genomics of pneumococcal carriage in South Africa following the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) immunization [0.03%]
13价肺炎球菌结合疫苗(PCV13)接种后南非肺炎球菌定植的群体基因组学分析
Nida Javaid,Courtney Olwagen,Susan Nzenze et al.
Nida Javaid et al.
Streptococcus pneumoniae is a major human pathogen responsible for over 317000 deaths in children
Identification and characterization of virus-encoded circular RNAs in host cells [0.03%]
宿主细胞中病毒源性环形RNA的鉴定与分析
Shuting Chen,Jie Zheng,Bingyue Zhang et al.
Shuting Chen et al.
Emerging evidence has identified viral circular RNAs (circRNAs) in human cells infected by viruses, interfering with the immune system and inducing diseases including human cancer. However, the biogenesis and regulatory mechanisms of virus-...
GR13-type plasmids in Acinetobacter potentiate the accumulation and horizontal transfer of diverse accessory genes [0.03%]
阿克托莫巴奈菌GR13型质粒促进多种辅助基因的积累和水平转移
Robert A Moran,Haiyang Liu,Emma L Doughty et al.
Robert A Moran et al.
Carbapenem and other antibiotic resistance genes (ARGs) can be found in plasmids in Acinetobacter , but many plasmid types in this genus have not been well-characterized. Here we describe the distribution, diversity and evolutionary capaci...
The niche-specialist and age-related oral microbial ecosystem: crosstalk with host immune cells in homeostasis [0.03%]
小众专长和年龄相关的口腔微生物生态系统：稳态下与宿主免疫细胞的相互作用
Dongjia Lin,Qiannan Hu,Lisa Yang et al.
Dongjia Lin et al.
Although characterization of the baseline oral microbiota has been discussed, the current literature seems insufficient to draw a definitive conclusion on the interactions between the microbes themselves or with the host. This study focuses...
Whole-genome sequencing enhances existing pathogen and antimicrobial-resistance surveillance schemes within a neonatal unit [0.03%]
全基因组测序可增强新生儿病室现有致病菌和抗菌药物耐药性监测方案
Vivien Price,Steven J Dunn,Robert A Moran et al.
Vivien Price et al.
In some neonatal units, the screening of isolates for antimicrobial-resistant organisms is a matter of routine, with theoretical benefits including the prevention or early detection of outbreaks. This study sought to use whole-genome sequen...
Insights into plastic biodegradation: community composition and functional capabilities of the superworm (Zophobas morio) microbiome in styrofoam feeding trials [0.03%]
超 worm(Zophobas morio)微生物组在泡沫聚苯乙烯取食实验中的组成和功能能力分析
Jiarui Sun,Apoorva Prabhu,Samuel T N Aroney et al.
Jiarui Sun et al.
Plastics are inexpensive and widely used organic polymers, but their high durability hinders biodegradation. Polystyrene, including extruded polystyrene (also known as styrofoam), is among the most commonly produced plastics worldwide and i...