Revisiting classical Escherichia coli cell division mutants by whole-genome sequencing [0.03%]
全基因组测序重新研究经典的大肠杆菌细胞分裂突变体
Elias Dahdouh,Isabel García-Pérez,Diana Soledad Reyes-Zuñagua et al.
Elias Dahdouh et al.
Over 60 years ago, researchers started the genetic analysis of bacterial cell division by isolating conditional, temperature-sensitive mutants of essential Escherichia coli cell division genes. These early mutants were obtained by mutagenes...
Genomic investigations in animal enteric disease-associated Clostridium perfringens [0.03%]
动物肠道疾病相关产气荚膜梭菌的基因组研究
Jan Franzen,Thomas Roder,Martin Larralde et al.
Jan Franzen et al.
The anaerobic bacterium Clostridium perfringens is commonly found in the intestinal tract of humans and animals. However, there are marked differences in virulence between isolates and toxinotypes, which largely depend on various virulence ...
Oxford nanopore sequencing as a useful tool for investigating the population dynamics of invasive begomoviruses in Sicily [0.03%]
牛津纳米孔测序作为一种研究入侵贝托摩病毒在西西里的种群动态的有用工具
Sofia Bertacca,Silvia Rotunno,Fulco Frascati et al.
Sofia Bertacca et al.
Tomato yellow leaf curl disease is a major viral disease severely affecting tomato crops in the Mediterranean region, leading to reduced crop yield and significant economic losses. The disease is caused by monopartite begomoviruses belongin...
Biodiscovery of Actinomycetota through metabolo-genomics reveals functional diversity across contrasting Mexican ecosystems [0.03%]
基于代谢组-基因组学的链霉菌目生物发现揭示了墨西哥不同生态系统中的功能多样性
Lorena Rodríguez-Orduña,César Aguilar,Alan Gerardo Hernández-Melgar et al.
Lorena Rodríguez-Orduña et al.
Discovery of novel bioactive natural products from Actinomycetota has decreased, motivating the exploration of rare ecosystems. In this work, we integrated genomics and untargeted metabolomics to profile the biosynthetic capacity of Strepto...
Evidence of diversification and geographic separation in a lineage of Campylobacter jejuni co-circulating in cattle and humans [0.03%]
证据表明Campylobacter jejuni同源菌株在宿主分离情况下发生种群分化
Jose A Rodrigues,Karla A Vasco,Heather M Blankenship et al.
Jose A Rodrigues et al.
Campylobacter jejuni, a leading cause of gastroenteritis, is acquired by consuming contaminated food products or via direct contact with animal reservoirs like cattle and poultry. Prior studies have identified specific C. jejuni lineages su...
Genomics reveals multiple introductions of the seventh pandemic Vibrio cholerae O1 El Tor lineage into Iran since 1965 [0.03%]
基因组学揭示第七次鼠疫弧菌霍乱O1埃尔托毒力亚型系自1965年以来多次进入伊朗
Bita Bakhshi,Elisabeth Njamkepo,Mozhgan Derakhshan-Sefidi et al.
Bita Bakhshi et al.
Cholera epidemics due to Vibrio cholerae O1 El Tor have been occurring in Iran since 1965, but the incidence of this disease has declined significantly over time. We found that multiple sublineages of the seventh pandemic V. cholerae O1 El ...
A multi-isolate genomic approach identifies diverse Escherichia coli contamination and antimicrobial resistance carriage on retail foods [0.03%]
基于多个菌株的基因组方法识别零售食物中大肠杆菌污染和抗生素抗性携带的多样性
Gabriel Astorga,Samuel J Bloomfield,Raphaëlle Palau et al.
Gabriel Astorga et al.
Background. Bacterial pathogens contaminating retail foods can cause foodborne illness. Escherichia coli is commonly enumerated on food to assess unsafe levels of faecal contamination, but E. coli as a species is genetically variable and di...
Temporal reconstruction of a Salmonella Enteritidis ST11 outbreak in New Zealand [0.03%]
新西兰志贺毒素型伤寒沙门氏菌ST11株的事件性发病时间推断研究
Hugo Strydom,Jackie Wright,Collette Bromhead et al.
Hugo Strydom et al.
Outbreaks caused by Salmonella Enteritidis are commonly linked to eggs and poultry meat internationally, but this serovar had never been detected in Aotearoa New Zealand (NZ) poultry prior to 2021. Locally designated genomic cluster Salmone...
Whole-genome analysis of rotavirus G1P[8] and other Wa-like strains in Mozambican children: evidence of genetic variations of pre-vaccine G1P[8] strains from Manhiça, Mozambique [0.03%]
莫桑比克马尼卡省轮状病毒G1P[8]和其他Wa样菌株的全基因组分析：来自莫桑比克马尼卡的疫苗前G1P[8]菌株遗传变异的证据
Filomena Manjate,Percina Chirinda,Peter Mwangi et al.
Filomena Manjate et al.
The Rotarix® (GlaxoSmithKline, Rixenstart, Belgium) vaccine was adopted into the Expanded Program on Immunization in Mozambique in September 2015, and G1P[8] strains were frequent pre- and post-vaccine introduction in some regions of the c...
An integrated multi-omic approach for discovery and dereplication of bioactive microbial natural products [0.03%]
一种用于生物活性微生物天然产物发现和脱重复的多组学综合研究方法
Negero Gemeda Negeri,Duong Duc Anh Nguyen,Michael Michael et al.
Negero Gemeda Negeri et al.
Soil bacteria are a major source of clinically useful antibiotics, yet the majority of soil-dwelling micro-organisms remain uncultivable by standard laboratory methods. To access this untapped microbial diversity, we employed microbial diff...