Evolution of genomic architecture of the plant-pathogenic fungus Alternaria revealed by comparative analyses of 12 chromosome-level assemblies [0.03%]
基于12个染色体水平基因组的比较分析揭示出植物病原真菌链格孢属的基因组结构演化
Jeremy R Dettman,Natalie E Kim,Kasia Dadej
Jeremy R Dettman
Gapless, chromosome-level assemblies provide unparalleled resolution for studying the architecture and evolution of genomes. We produced new telomere-to-telomere genome assemblies for five strains representing four species from the plant-pa...
Comparative Study
Microbial genomics. 2026 Apr;12(4):001686. DOI:10.1099/mgen.0.001686 2026
Host-anellovirus interactions in an island ecosystem: non-human primates and rodents in Madagascar harbour diverse, rich anellovirus populations [0.03%]
孤岛上宿主与痘病毒的相互作用：马达加斯加非人类灵长类动物和啮齿动物中丰富的环状病毒群落
Elise N Paietta,Rachel A Johnston,Santatriniaina F Randrianarisoa et al.
Elise N Paietta et al.
Anelloviruses are circular, negative-sense single-stranded DNA viruses that have remarkable diversity and ubiquity across mammals. However, few studies have attempted to determine anellovirus diversity and dynamics across a biodiverse lands...
Genomic and statistical models to characterize Streptococcus pneumoniae transmission patterns in Malawi [0.03%]
马拉维肺炎链球菌传播模式的基因组和统计模型研究
Rory Cave,James Chirombo,Uri Obolski et al.
Rory Cave et al.
Controlling the carriage and transmission of Streptococcus pneumoniae in children from high-burden settings is critical for disease prevention. To investigate the rate and drivers of transmission following pneumococcal conjugate vaccine (PC...
Public and patient involvement: exploring public partnership in pathogen whole-genome sequencing research and its data visualisation [0.03%]
公共和患者参与：探索病原体全基因组测序研究及其数据可视化中的公众伙伴关系
Suzanne Rotheram,Hannah Trivett,Jane Whitehurst et al.
Suzanne Rotheram et al.
Pathogen genomics is increasingly used in publicly funded studies and has important implications for understanding infectious diseases and their spread. However, unlike many other research areas, it has seen little patient and public involv...
Genomic characterization of mobile genetic elements associated with antimicrobial resistance in Streptococcus pneumoniae from Australia [0.03%]
澳大利亚肺炎链球菌耐药性相关可移动遗传元件的基因组表征
Gabriel Temitope Sunmonu,Rosa C Coldbeck-Shackley,Rikki M A Graham et al.
Gabriel Temitope Sunmonu et al.
The emergence and spread of antimicrobial resistance (AMR) in Streptococcus pneumoniae threatens current antibiotic treatment strategies. While β-lactams remain the first-line therapy for pneumococcal infections in Australia, resistance to...
Comparative genomic and resistance characterization of ST2 and ST164 carbapenem-resistant Acinetobacter baumannii from hospital environments and clinical specimens [0.03%]
来自医院环境和临床标本的O型血耐碳青霉烯类抗生素的baumannii的基因组和抗性特征比较分析
Xiao Wang,Tongsheng Xu,Yue Zhang et al.
Xiao Wang et al.
Carbapenem-resistant Acinetobacter baumannii (CRAB) represents a formidable nosocomial pathogen, with healthcare environments acting as critical reservoirs for its dissemination. In this study, we investigated the prevalence, antimicrobial ...
Genomic epidemiology of Mycobacterium tuberculosis in Malawi: using global phylogeography to understand the impact of geographically focused interventions [0.03%]
马拉维结核分枝杆菌基因组流行病学：利用全球谱系地理来了解地理聚焦干预措施的影响
Alexander B Beams,Yexuan Song,Jennifer McNichol et al.
Alexander B Beams et al.
Genomic surveillance of pathogens important to public health, such as Mycobacterium tuberculosis (Mtb), offers the opportunity to characterize the geographic movements of pathogens on a range of spatial and temporal scales and to explore th...
Functional shifts of the dual-substrate phosphoribosyl isomerase PriA from primary to specialized metabolism in rare Actinomycetota [0.03%]
罕见放线菌门中双底物磷酸核糖异构酶PriA从初级代谢向专业代谢的功能转移
Luis Rodrigo Rosas-Becerra,Andrés Arredondo-Cruz,Nelly Sélem-Mojica et al.
Luis Rodrigo Rosas-Becerra et al.
Evolutionary functional innovations can occur while gene families expand and two homologous (or analogous) genes co-occur. PriA is a dual-substrate enzyme family exclusive to Actinomycetota, with activities in l-histidine and l-tryptophan b...
The novel pseudo-compound transposon Tn 7086 carries aminoglycoside resistance genes in Enterococcus faecalis [0.03%]
新的假复合转座子Tn7086含有耐氨基糖苷类基因并存在于粪链球菌中
Lorenzo Colombini,Mariana Tirziu,Stefano De Giorgi et al.
Lorenzo Colombini et al.
Enterococcus faecalis is a member of the human gut microbiota and a pathogen responsible for mild and severe infections. Here, genome analysis of E. faecalis strains isolated from different body sites revealed the presence of a novel family...
Lifestyle-associated variation in type IV secretion systems between phytopathogenic and environmental Ralstonia [0.03%]
植物致病性和环境条件下的Ralstonia菌群中IV型分泌系统的差异性分析
Tabitha C Cowell,Matthew L Cope-Arguello,Gi Yoon Shin et al.
Tabitha C Cowell et al.
Type IV secretion systems (T4SSs) are versatile machines with variable functions including DNA uptake and release, protein translocation, and DNA conjugation. However, the diversity, distribution, and functional roles of the T4SS in the Ral...