Genomic characterization of invasive Streptococcus pneumoniae isolates from a southern Taiwan medical centre, 2015-2023 [0.03%]
2015年至2023年台湾南部医疗中心侵袭性肺炎链球菌分离株的基因组特征分析
Poyen Liu,Anne-Kathryn Venero,Theresa Tran et al.
Poyen Liu et al.
Since the introduction of pneumococcal conjugate vaccines, the incidence of invasive pneumococcal disease (IPD) among children has decreased significantly. The distribution of IPD cases has shifted towards other vulnerable populations, incl...
Genome-wide characterization of sulphur metabolism gene families and recombination dynamics in mangrove-derived Bacillus aryabhattai NM1-A2 and Bacillus cereus NR1 [0.03%]
源自红树的枯草芽胞杆菌NM1-A2和NR1硫代谢基因家族及重组动力学的全基因组表征
Muhammad Kashif,Tingmei Li,Dan Wang et al.
Muhammad Kashif et al.
This study presents a comprehensive genome-wide analysis of sulphur metabolism-related gene families in Bacillus aryabhattai strain NM1-A2 and Bacillus cereus strain NR1, isolated from marine mangrove habitats. We investigated phylogenetic ...
The effects of bacteriophage cocktail treatment on healthy gut microbiota: an in vitro human colon model study [0.03%]
噬菌体鸡尾酒疗法对健康肠道微生物群的影响：体内人体结肠模型研究
Teagan L Brown,Duncan Y K Ng,George M Savva et al.
Teagan L Brown et al.
The human gut microbiome is a complex community that plays an important role in health, where perturbations can result in dysbiosis and disease. Bacteriophages (phages) can provide treatment for bacterial gastrointestinal disease, and comme...
Using pangenome variation graphs to improve mutation detection in a large DNA virus [0.03%]
利用泛基因组变异图改进大型DNA病毒中的突变检测
Tim Downing,Chandana Tennakoon,Lidia Lasecka-Dykes et al.
Tim Downing et al.
Accurately quantifying viral genetic diversity is essential for understanding pathogen evolution, transmission and emergence. However, standard approaches that map sequencing reads to a single linear reference genome introduce substantial r...
Unveiling metagenomic and metabolomic signatures in mild and severe pneumonia caused by Mycoplasma pneumoniae in children [0.03%]
儿童支原体肺炎轻型和重型的元基因组和代谢组特征分析
Yeran Yang,Shitao Lian,Xiao Li et al.
Yeran Yang et al.
Background. Mycoplasma pneumoniae (MP) is a common causative pathogen of community-acquired pneumonia in children, with clinical presentations ranging in severity. Early stratification and timely intervention are essential for improving pat...
Towards accurate genomic detection of fungal antimicrobial resistance: progress in fungal resistance databases and bioinformatic tools [0.03%]
迈向准确的真菌抗微生物基因组检测：真菌耐药数据库和生物信息学工具的研究进展
Andrew P Gador-Whyte,Johanna Rhodes,Rhys A Farrer et al.
Andrew P Gador-Whyte et al.
Fungal antimicrobial resistance (fAMR) is increasing worldwide and is recognized as a global health priority by the World Health Organization. The emergence of Candidozyma (Candida) auris and other resistant fungal pathogens presents a risk...
Uncovering resistance pathways to first- and last-line antibiotics in Mycobacterium tuberculosis populations [0.03%]
揭示结核分枝杆菌菌群中一线和二线抗生素的耐药途径
Prapaporn Srilohasin,Jasmine M Williams,Aidan P Tay et al.
Prapaporn Srilohasin et al.
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the world's deadliest diseases, currently responsible for ~1.5 million deaths per year and rising. Recently, rifampicin-resistant M. tuberculosis was designated as a critica...
Genetic structure of penicillin non-susceptible invasive Streptococcus pneumoniae in Colombia [0.03%]
哥伦比亚耐青霉素侵袭性肺炎链球菌的遗传结构
Jamie Moreno,Johan F Bernal,Monica Abrudan et al.
Jamie Moreno et al.
Background. Infections caused by Streptococcus pneumoniae are a public health problem worldwide, and penicillin-non-susceptible isolates are a priority for the World Health Organization, which requires further research and development of ne...
Phylogenomic and metabolic insights into iron reduction metabolism in the genus Deferribacter belonging to the order Deferribacterales [0.03%]
铁还原菌属铁还原代谢的生理基因组和代谢见解
Eva Pouder,Karine Alain,Sophie Mieszkin
Eva Pouder
Iron is one of the most important elements of the Earth, yet its bioavailability is limited in oceanic environments. In this context, deep-sea hydrothermal ecosystems represent one of the major sources of iron. While some microorganisms inv...
Conservation, origin, and remodeling of the phenyl acetate degradation pathway [0.03%]
苯乙酸降解途径的保护、起源和重建
Jimena Arreola-Calderon,Juan-Manuel Hurtado-Ramirez,Erick Cruz-Santiago et al.
Jimena Arreola-Calderon et al.
Aromatic hydrocarbons are widespread environmental compounds whose microbial degradation is essential for detoxification, yet the genomic distribution and evolutionary stability of many catabolic pathways remain poorly understood. The pheny...