Beyond livestock: the genomic evolution and expansion of MRSA CC398 as a healthcare- and community-associated pathogen (2017-2024) [0.03%]
超越家畜：MRSA菌株CC398作为医疗和社区相关病原体的基因组演化及扩展（2017-2024）
Jan Tkadlec,Adela Rozsypalkova,Sylvia Polivkova et al.
Jan Tkadlec et al.
This study employed whole-genome sequencing to elucidate the genomic diversity and population structure of Staphylococcus aureus clonal complex 398 (CC398) in the Czech Republic over a 7-year period (2017-2024). Among 1,129 MRSA isolates fr...
Clonal expansion of global pneumococcal sequence cluster 3 within serotype 8 after 13-valent pneumococcal conjugate vaccine introduction, South Africa [0.03%]
13价肺炎球菌结合疫苗引入后血清型8中的全球肺炎球菌序列群系3的克隆扩增，南非
Cebile Lekhuleni,Kedibone Ndlangisa,Ana D Sanches Ferreira et al.
Cebile Lekhuleni et al.
Background. Serotype 8 has emerged as a common non-vaccine serotype causing invasive pneumococcal disease (IPD) in children and adults globally after the introduction of pneumococcal conjugate vaccines (PCV). We aimed to determine serotype ...
Hybrid sequencing reveals incompleteness of the H37Rv reference genome and highlights lineage-specific genomic divergence in Mycobacterium tuberculosis [0.03%]
杂交测序揭示了H37Rv参考基因组的不完整性，并强调了结核分枝杆菌中的谱系特异性基因组分歧现象
Haiting Chen,Xiangchen Li,Ruiqi Chen et al.
Haiting Chen et al.
Background. The Mycobacterium tuberculosis H37Rv reference genome (Lineage 4), sequenced in 1998, may be incomplete and inaccurate due to earlier technology. Moreover, its use is problematic in regions like East Asia where the dominant Beij...
Emergence and dissemination of extensively drug-resistant ST307 Klebsiella pneumoniae in China [0.03%]
中国广泛流行的产超广谱酶ST307型肺炎克雷伯菌的产生及传播机制研究
Weihua Han,Xinru Yuan,Can Yang et al.
Weihua Han et al.
Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat to global public health. Identifying high-risk clones that facilitate the global dissemination of carbapenemases is essential for developing effective strategies t...
From classification to confirmation: verifying taxonomic classifications by mapping metagenomic reads to reference genomes [0.03%]
从分类到确认：通过将元基因组读段映射到参考基因组来验证分类学分类
Robyn J Wright,Benjamin R Fisher,André M Comeau et al.
Robyn J Wright et al.
Obtaining high precision while maintaining high recall is an ongoing problem for metagenomic taxonomic classification in microbial ecology research. Parameter adjustments can achieve this in simulated samples, but in real samples - especial...
Integrative and conjugative elements carrying high-level gentamicin resistance genes in Streptococcus dysgalactiae subsp. equisimilis from horses [0.03%]
来自马的牛链球菌亚种中携带高水平新霉素抗性基因的整合和接合元件
Tony Rochegüe,Sandrine Hughes,Estelle Saras et al.
Tony Rochegüe et al.
In streptococci, the acquisition of high-level gentamicin resistance (HLGR) abolishes the synergy with beta-lactams, constituting a medical concern for humans and animals. This synergy between gentamicin and beta-lactams is useful to treat ...
Sulphur metabolism as a key factor in the evolution of environmental adaptation of Acidihalobacter [0.03%]
硫代谢在酸盐嗜卤菌环境适应性进化中的作用
Eva Vergara,Himel Nahreen Khaleque,Gonzalo Neira et al.
Eva Vergara et al.
This study compares predicted sulphur metabolism genes across four Acidihalobacter type strains and two metagenome-assembled genomes (MAGs), revealing genomic differences that appear to correspond to ecological specialization. Phylogenomic ...
Diversity and prevalence of dairy streptococcal phages in two European dairy fermentation facilities over a one-year period [0.03%]
欧洲两个乳制品发酵厂一年期间的乳品链球菌噬菌体的多样性和流行度
Kelsey White,Joanna Danuta Szafran,Brian McDonnell et al.
Kelsey White et al.
Bacteriophages (or phages) represent a major challenge to industrial dairy fermentations and may cause reduced acidification of the milk substrate. Streptococcus thermophilus is a thermophilic lactic acid bacterium widely used in dairy ferm...
Direct nanopore sequencing of Mycobacterium tuberculosis on sputa and rescue of suboptimal results to enhance transmission surveillance [0.03%]
结核分枝杆菌直接纳米孔测序及其次优结果的挽救以增强传播监测
Sheri M Saleeb,Andrea Marcos-Abellán,María Teresa Cabezas Fernández et al.
Sheri M Saleeb et al.
Whole-genome sequencing (WGS) has enhanced precision to predict antimicrobial resistance and track transmission in Mycobacterium tuberculosis (MTB). Due to the slow-growing nature of MTB, genomic results are unavoidably delayed; however, fe...
Mammal-infecting DNA viruses identified in lemurs and rodents in Madagascar mirror the evolutionary history of their hosts [0.03%]
在马达加斯加灵长类动物和啮齿动物中发现的感染哺乳动物的DNA病毒反映了宿主的进化历史
Elise N Paietta,Rachel A Johnston,Simona Kraberger et al.
Elise N Paietta et al.
Given that some DNA viruses have been found to exhibit virus-host co-evolution and establish lifelong infection, mammals with unique evolutionary histories in island ecosystems likely host exceptionally diverse viruses. Madagascar is inhabi...