Time-resolved comparative genomics of ' Candidatus Carsonella ruddii' across psyllid lineages reveals a conserved core genome and contrasting secondary symbiont dynamics [0.03%]
卡戎星卡尔森内拉古德迪种时间解析比较基因组学：保守的核心基因组与对比明显的次要共生菌动力学
Fengnian Wu,Kangyi Deng,Xiuxuan Lin et al.
Fengnian Wu et al.
Psyllids harbour the obligate nutritional symbiont 'Candidatus Carsonella ruddii' (CaCr), yet complete CaCr genomes remain unevenly sampled across Psylloidea, limiting both comparative analysis and temporal inference. Here, seven complete C...
Rapid identification of microbial pathogens and antimicrobial resistance from bloodstream infections using long-read sequencing [0.03%]
基于长读取测序技术快速识别血流感染中的微生物病原体和抗微生物药物耐药性
Nicole Lerminiaux,Ken Fakharuddin,Heather J Adam et al.
Nicole Lerminiaux et al.
The gold standard for bloodstream infection (BSI) diagnostics involves culturing positive blood cultures (BCs) using phenotypic methods for organism identification and antimicrobial resistance (AMR) testing, which can take up to five days. ...
Pseudogenization of the chaperonin system in ' Candidatus Phytoplasma pruni' revealed by genome sequencing and comparative genomics [0.03%]
基因组测序和比较基因组学揭示了皮托普拉斯基亚类葡萄植原体(chaperonin系统)的假基因化
Thierry Alexandre Pellegrinetti,Christine Hammond,Edel Pérez-López et al.
Thierry Alexandre Pellegrinetti et al.
GroE is a chaperonin folding system consisting of GroEL (Cpn60, a 60 kDa chaperonin), and the smaller co-chaperonin GroES (Cpn10). Many 'client' proteins require GroE to fold properly, including several that are essential for cell viability...
Daniel J Nebauer,Tiffanie Nelson,Caitlin Romanis et al.
Daniel J Nebauer et al.
The recovery of metagenome-assembled genomes (MAGs) from shotgun metagenomic sequencing is rapidly expanding the availability of representative genomes. However, this practice may skew the representation of specific taxa in real-world datas...
Genomic diversity and virulence of Pasteurella multocida in Norwegian calves [0.03%]
挪威牛分枝杆菌溶血素基因多态性与毒力研究
Asal Ahmadi,Veslemøy Sunniva Oma,Lise Marie Ånestad et al.
Asal Ahmadi et al.
The bovine respiratory disease (BRD) complex is a major health and welfare challenge in the cattle industry worldwide, with substantial economic and antimicrobial resistance implications. Pasteurella multocida (PM) is a key bacterial agent ...
Andreas C Lawaetz,Alexa Gannon,Paul A Hoskisson
Andreas C Lawaetz
Most antibiotics are derived from Streptomyces bacteria and produced industrially via fermentations relying on food-grade feedstocks, which have a substantial environmental impact. Efficient utilization of starch-rich organic wastes, such a...
2026 Bundibugyo virus outbreak: the role of genomics in Orthoebolavirus outbreaks [0.03%]
2026年邦迪博约病毒疫情暴发：正埃博拉病毒属疫情中的基因组学作用
Charlotte J Houldcroft
Charlotte J Houldcroft
Central Africa is currently experiencing its third recorded outbreak of Bundibugyo virus, one of three orthoebolaviruses capable of causing lethal haemorrhagic fevers in humans with person-to-person transmission. The first genomes from this...
Deciphering the pangenome of the shellfish pathogen Vibrio europaeus: evolutionary history and functional impact of core and accessory genes in aquaculture [0.03%]
虾夷弧菌泛基因组的解析：核心和辅助基因在养殖中的进化历史及功能影响
Sergio Rodriguez,Diego Rey-Varela,Andrés Blanco-Hortas et al.
Sergio Rodriguez et al.
Vibrio europaeus is an important pathogen in shellfish aquaculture, yet its genomic diversity remains poorly understood. Here, we present the first comprehensive analysis of the V. europaeus pangenome, integrating genomic data from all stra...
Carolin M Kobras,Seungwon Ko,Priyanshu S Raikwar et al.
Carolin M Kobras et al.
Rapid, low-cost genome sequencing has transformed microbiology, advancing efforts to link genetic and phenotypic variation across diverse bacterial systems. Laboratory functional screens now uncover causal mechanisms underlying key traits i...
Whole-genome analysis of a novel Pandoraea sputorum lineage causing high-mortality bloodstream infections [0.03%]
全基因组分析新型解耳霉菌引起高致死率血流感染的新谱系
Hua Wu,Lin Liu,Shijia Li et al.
Hua Wu et al.
Background. Pandoraea sputorum is an emerging multidrug-resistant pathogen primarily associated with cystic fibrosis. Bloodstream infections (BSIs) are rare but linked to high mortality. The genomic characteristics and evolutionary history ...