Mapping potential pathogen profiling in cetacean blow: comparative insights from sequencing technologies [0.03%]
鲸鱼喷雾潜在病原体谱系测定的路径学：来源于测序技术的比较见解
Johann Frederick Jaitner,Nicola Gambardella,Luís Afonso et al.
Johann Frederick Jaitner et al.
Cetaceans play a critical role in marine ecosystems and function as sentinel species for detecting environmental perturbations, underscoring the importance of assessing their health for effective marine conservation. This study employed 16S...
Comparative Study
Microbial genomics. 2026 Jul;12(7):001773. DOI:10.1099/mgen.0.001773 2026
A microbial mirage: when microbiome metrics may obscure ecological meaning [0.03%]
微生物指标的误导：当微生物组计量可能掩盖生态意义时
Jake M Robinson,Linda Guentas,Martin F Breed
Jake M Robinson
Metrics such as alpha diversity, inferred functional potential and network complexity have become standard metrics in microbiome research. While they offer convenient ways to summarize complex data, these metrics may sometimes obscure more ...
Amanda Araujo Serrao de Andrade,Andrea Silverj,Theodore Josephs et al.
Amanda Araujo Serrao de Andrade et al.
Viruses interact with all domains of life and play fundamental roles in shaping biological systems from individual hosts to global ecosystems. Yet their identification remains difficult due to a lack of a universal marker gene and the exten...
Stabilizing features of cefotaximase harbouring plasmids enable persistence in UK livestock [0.03%]
携带头孢他啶酶的质粒的稳定特征可使该菌在英国家畜中持续存在
Nicholas Duggett,Daisy E Gates,Manal AbuOun et al.
Nicholas Duggett et al.
Extended-spectrum cephalosporinases (ESCs) confer resistance to a range of beta-lactam compounds, including many cephalosporins and have grown in prevalence since the early 2000s. ESCs are often disseminated via plasmids, which can also enc...
Genomic analysis of intrahospital transmission of carbapenem-resistant Gram-negative bacteria: a multicentre study in Japan [0.03%]
日本多中心碳青霉烯耐药革兰氏阴性杆菌院内传播的基因组学分析研究
Yasufumi Matsumura,Yohei Doi,Kayoko Hayakawa et al.
Yasufumi Matsumura et al.
We aimed to identify genomically defined strain transmission events of carbapenem-resistant Gram-negative bacteria (CRGNB) in hospitals, estimate species-specific transmission rates and identify risk factors for transmission. The study incl...
Multicenter Study
Microbial genomics. 2026 Jul;12(7):001770. DOI:10.1099/mgen.0.001770 2026
Comparative genomics and methylome profiling of Pseudolactococcus laudensis reveal signatures of niche adaptation and strain-level variation in mobile genetic elements and phage defence [0.03%]
比较基因组学和甲基化组分析揭示了Pseudolactococcus laudensis适应生态位和菌株水平的可移动遗传元件以及噬菌体防御的标志物
Axel Soto-Serrano,Tamas Vincze,Richard J Roberts et al.
Axel Soto-Serrano et al.
Pseudolactococcus laudensis (formerly named Lactococcus laudensis) is an emerging lactic acid bacterium first isolated from raw milk in 2015 and subsequently detected in vegetables and dairy mesophilic starter cultures. Despite its recurren...
Culture-enriched metagenomic sequencing reveals within-patient diversity and transmission of vancomycin-resistant Enterococcus faecium [0.03%]
改良的宏基因组测序揭示了肠球菌内的万古霉素耐药多样性和传播状况
Emma G Mills,Kirsten M Evans,Ava J Dorazio et al.
Emma G Mills et al.
Colonization of the gastrointestinal (GI) tract by vancomycin-resistant Enterococcus faecium (VREfm) often precedes bloodstream infection and serves as a reservoir for onward patient transmission in healthcare settings. Routine clonal isola...
New isolates from the 1970s to early 2000s provide insights into the evolution of Acinetobacter baumannii international clone 2 and its resistome [0.03%]
从二十世纪七十年代到本世纪初的新分离株为国际流行克隆2耐药性基因组演化提供见解
Matthew Neil,Frédéric Grenier,Nancy Allard et al.
Matthew Neil et al.
Acinetobacter baumannii remains a pervasive nosocomial pathogen, with international clone 2 (IC2) being the most successful lineage. IC2 is often discussed as a singular entity, and the genomic factors behind its success over other lineages...
Comprehensive identification of sequence types belonging to Acinetobacter baumannii clonal complexes [0.03%]
肠杆菌属baumannia亚种克隆复合群序列型的全面鉴定
Ruth M Hall,Christopher J Harmer
Ruth M Hall
Acinetobacter baumannii is a major nosocomial pathogen, with multiply antibiotic-resistant (MAR) isolates primarily belonging to two globally disseminated clonal complexes, Global Clone 1 (GC1) and Global Clone 2 (GC2). A. baumannii has two...
Genomic outbreak investigation of biosafety-level-3 pathogens using nanopore sequencing [0.03%]
利用纳米孔测序技术进行三级生物安全实验室病原体的基因组爆发调查
Christine Francesca Thomas,Hanka Brangsch,Herbert Tomaso et al.
Christine Francesca Thomas et al.
Background. Accurate outbreak analysis is essential for effective infectious disease control. While short-read Illumina sequencing is the current gold standard for genotyping pathogens, Oxford Nanopore Technologies (ONT) offers advantages s...