Daniel J Nebauer,Tiffanie Nelson,Caitlin Romanis et al.
Daniel J Nebauer et al.
The recovery of metagenome-assembled genomes (MAGs) from shotgun metagenomic sequencing is rapidly expanding the availability of representative genomes. However, this practice may skew the representation of specific taxa in real-world datas...
Genomic diversity and virulence of Pasteurella multocida in Norwegian calves [0.03%]
挪威牛分枝杆菌溶血素基因多态性与毒力研究
Asal Ahmadi,Veslemøy Sunniva Oma,Lise Marie Ånestad et al.
Asal Ahmadi et al.
The bovine respiratory disease (BRD) complex is a major health and welfare challenge in the cattle industry worldwide, with substantial economic and antimicrobial resistance implications. Pasteurella multocida (PM) is a key bacterial agent ...
Andreas C Lawaetz,Alexa Gannon,Paul A Hoskisson
Andreas C Lawaetz
Most antibiotics are derived from Streptomyces bacteria and produced industrially via fermentations relying on food-grade feedstocks, which have a substantial environmental impact. Efficient utilization of starch-rich organic wastes, such a...
2026 Bundibugyo virus outbreak: the role of genomics in Orthoebolavirus outbreaks [0.03%]
2026年邦迪博约病毒疫情暴发：正埃博拉病毒属疫情中的基因组学作用
Charlotte J Houldcroft
Charlotte J Houldcroft
Central Africa is currently experiencing its third recorded outbreak of Bundibugyo virus, one of three orthoebolaviruses capable of causing lethal haemorrhagic fevers in humans with person-to-person transmission. The first genomes from this...
Deciphering the pangenome of the shellfish pathogen Vibrio europaeus: evolutionary history and functional impact of core and accessory genes in aquaculture [0.03%]
虾夷弧菌泛基因组的解析：核心和辅助基因在养殖中的进化历史及功能影响
Sergio Rodriguez,Diego Rey-Varela,Andrés Blanco-Hortas et al.
Sergio Rodriguez et al.
Vibrio europaeus is an important pathogen in shellfish aquaculture, yet its genomic diversity remains poorly understood. Here, we present the first comprehensive analysis of the V. europaeus pangenome, integrating genomic data from all stra...
Carolin M Kobras,Seungwon Ko,Priyanshu S Raikwar et al.
Carolin M Kobras et al.
Rapid, low-cost genome sequencing has transformed microbiology, advancing efforts to link genetic and phenotypic variation across diverse bacterial systems. Laboratory functional screens now uncover causal mechanisms underlying key traits i...
Whole-genome analysis of a novel Pandoraea sputorum lineage causing high-mortality bloodstream infections [0.03%]
全基因组分析新型解耳霉菌引起高致死率血流感染的新谱系
Hua Wu,Lin Liu,Shijia Li et al.
Hua Wu et al.
Background. Pandoraea sputorum is an emerging multidrug-resistant pathogen primarily associated with cystic fibrosis. Bloodstream infections (BSIs) are rare but linked to high mortality. The genomic characteristics and evolutionary history ...
Beyond livestock: the genomic evolution and expansion of MRSA CC398 as a healthcare- and community-associated pathogen (2017-2024) [0.03%]
超越家畜：MRSA菌株CC398作为医疗和社区相关病原体的基因组演化及扩展（2017-2024）
Jan Tkadlec,Adela Rozsypalkova,Sylvia Polivkova et al.
Jan Tkadlec et al.
This study employed whole-genome sequencing to elucidate the genomic diversity and population structure of Staphylococcus aureus clonal complex 398 (CC398) in the Czech Republic over a 7-year period (2017-2024). Among 1,129 MRSA isolates fr...
Clonal expansion of global pneumococcal sequence cluster 3 within serotype 8 after 13-valent pneumococcal conjugate vaccine introduction, South Africa [0.03%]
13价肺炎球菌结合疫苗引入后血清型8中的全球肺炎球菌序列群系3的克隆扩增，南非
Cebile Lekhuleni,Kedibone Ndlangisa,Ana D Sanches Ferreira et al.
Cebile Lekhuleni et al.
Background. Serotype 8 has emerged as a common non-vaccine serotype causing invasive pneumococcal disease (IPD) in children and adults globally after the introduction of pneumococcal conjugate vaccines (PCV). We aimed to determine serotype ...
Hybrid sequencing reveals incompleteness of the H37Rv reference genome and highlights lineage-specific genomic divergence in Mycobacterium tuberculosis [0.03%]
杂交测序揭示了H37Rv参考基因组的不完整性，并强调了结核分枝杆菌中的谱系特异性基因组分歧现象
Haiting Chen,Xiangchen Li,Ruiqi Chen et al.
Haiting Chen et al.
Background. The Mycobacterium tuberculosis H37Rv reference genome (Lineage 4), sequenced in 1998, may be incomplete and inaccurate due to earlier technology. Moreover, its use is problematic in regions like East Asia where the dominant Beij...