Resolving plasmid-encoded carbapenem resistance dynamics and reservoirs in a hospital setting through nanopore sequencing [0.03%]
基于纳米孔测序的医院环境中碳青霉烯耐药质粒的分布及储存库解析
Ela Sauerborn,Rhys T White,Anna-Lena Kalteis et al.
Ela Sauerborn et al.
The growing resistance of Enterobacterales to last-resort antibiotics such as carbapenems puts a significant burden on healthcare systems, also due to plasmids driving a rapid spread of carbapenem resistance. We here evaluate the use of lon...
Bringing the band back together: eukaryotic microbes in microbial genomics [0.03%]
带齐乐队归来：真核微生物在微生物基因组学中的地位
Eva Heinz,Fiona L Henriquez,Virginia M Howick
Eva Heinz
Sequence type and strain-level detection of Klebsiella pneumoniae in culture-enriched bacterial metagenomes: comparative performance of mSWEEP and StrainGE bioinformatic tools [0.03%]
基于mSWEEP和StrainGE生物信息工具的肺炎克雷伯菌序列类型及毒株水平检测：宏基因组中富集细菌的比较性能分析
Dorota Julia Buczek,Wasifa Kabir,Kenneth Lindstedt et al.
Dorota Julia Buczek et al.
Klebsiella pneumoniae is a major cause of human infections and is frequently associated with antimicrobial resistance (AMR). Carriage of K. pneumoniae in the gut is a major risk factor for infection and a reservoir for the spread of high-ri...
Comparative Study
Microbial genomics. 2026 Feb;12(2):001638. DOI:10.1099/mgen.0.001638 2026
Corrigendum: Biodiscovery of Actinomycetota through metabolo-genomics reveals functional diversity across contrasting Mexican ecosystems [0.03%]
订正：通过元代谢组学揭示墨西哥不同生态系统中放线菌的生物发现及其功能多样性
Lorena Rodríguez-Orduña,César Aguilar,Alan Gerardo Hernández-Melgar et al.
Lorena Rodríguez-Orduña et al.
Published Erratum
Microbial genomics. 2026 Feb;12(2):001641. DOI:10.1099/mgen.0.001641 2026
Dynamics of a large multidrug-resistant plasmid encoding New Delhi metallo-β-lactamase-1 and oxacillinase-58 carbapenemases in Acinetobacter baumannii clinical isolates from a tertiary hospital in Malaysia [0.03%]
携带新德里金属β-内酰胺酶-1和氧氮杂环戊烷-58碳青霉烯酶的大肠杆菌临床分离株的大马来亚三级医院多药耐药质粒的动力学特征
Nurul Saidah Din,Farahiyah Mohd Rani,Salwani Ismail et al.
Nurul Saidah Din et al.
Acinetobacter baumannii carrying the bla NDM-1 gene, which encodes New Delhi metallo-β-lactamase-1 (NDM-1), exhibits resistance to nearly all β-lactams and is not affected by β-lactamase inhibitors, limiting treatment options. The bla ND...
Whole-genome sequencing reveals genetic diversity and transmission dynamics of Mycobacterium bovis in South African wildlife [0.03%]
全基因组测序揭示了南非野生动物中牛型结核分枝杆菌的遗传多样性及传播动力学
Abisola Okunola,Johannes Loubser,Giovanni Ghielmetti et al.
Abisola Okunola et al.
Mycobacterium bovis infection poses a significant threat to the biodiversity and conservation of South African wildlife. Despite this, few studies have explored transmission dynamics within these complex multi-host systems. This study used ...
Genome sequencing reveals variation of African swine fever virus in Nigerian outbreaks and identification of two major West African viral lineages [0.03%]
基因组测序揭示尼日利亚猪瘟疫情中的非洲猪瘟病毒的变异并鉴定出两条主要西非毒株谱系
Ganih S Joel,Anvou R Jambol,Nenfort Daniel Jahota et al.
Ganih S Joel et al.
African swine fever is a transboundary disease of wild boar and domestic pigs that is caused by the African swine fever virus (ASFV), with a mortality rate of 100 % in naïve animals. The ongoing spread poses a significant threat to food se...
Evaluation of Oxford Nanopore Technologies workflows for genomic epidemiology of outbreak-associated bacterial isolates in the clinical setting [0.03%]
牛津纳米孔技术在临床环境中爆发相关细菌分离物基因组流行病学研究中的评估
Stefan Neuenschwander,Loïc Borcard,Sonja Gempeler et al.
Stefan Neuenschwander et al.
Accurate and efficient whole-genome sequencing (WGS) is crucial for clinical diagnostics and surveillance of bacterial infections. Here, we investigate the potential of a new Oxford Nanopore Technologies (ONT) workflow for WGS of clinically...
Phylogenomic and phenotypic profiling of carbapenem-resistant Pseudomonas aeruginosa clinical isolates reveals lineage-specific resistance mechanisms and adaptive responses [0.03%]
铜绿假单胞菌碳青霉烯耐药临床分离株的泛基因组和表型谱分析揭示了谱系特异性耐药机制及适应性响应
Humberto Torres-Rodríguez,Elvira Garza-González,Claudia Adriana Colín-Castro et al.
Humberto Torres-Rodríguez et al.
Carbapenem resistance in Pseudomonas aeruginosa is a growing public health concern. Multiple mechanisms of antimicrobial resistance have been described. While surveillance often focuses on carbapenemase detection, non-carbapenemase mechanis...
Genomic insights into the functional and metabolic versatility of gut microbiome Anaerostipes species [0.03%]
基因组学见解揭示肠道微生物Anaerostipes属的功能和代谢多样性
Disha Bhattacharjee,Lindsey C Millman,Meagan L Seesengood et al.
Disha Bhattacharjee et al.
Members of the class Clostridia, a polyphyletic group of pathogenic and beneficial Gram-positive, spore-forming anaerobes in the Bacillota (Firmicutes) phylum, are prevalent in the human gut. While this class includes select pathogens known...