Metagenomic analysis of UK retail foods finds limited evidence for associations between food production method and antimicrobial resistance gene burden [0.03%]
英国零售食品的元基因组分析表明，食品生产方法和耐药基因负担之间的关系证据有限
Sam A Mellor,Samuel J Bloomfield,Raphaëlle Palau et al.
Sam A Mellor et al.
Food is produced by a range of methods including extensive (organic and free range), intensive (conventional) and wild-caught production systems. Antimicrobial use varies between different food production systems, which may affect the micro...
Nanopore direct RNA sequencing reveals transmissible gastroenteritis virus epitranscriptomic and transcriptomic landscapes modulated by gene 7 [0.03%]
纳米孔直接RNA测序揭示了由基因7调控的传染性胃肠炎病毒表转录组和转录组图谱
Qingqiu Jiang,Zhihao Guo,Lu Tan et al.
Qingqiu Jiang et al.
Viral non-structural proteins are key mediators of host-virus interplay, including RNA modification dynamics. The function of the transmissible gastroenteritis virus (TGEV) gene 7, which encodes a non-structural protein, remains poorly unde...
Genomic features and the transcriptional regulation of secondary metabolite biosynthesis of endophytic fungus Xylaria sp. VDL4 isolated from Vaccinium dunalianum [0.03%]
从越橘中分离出的内生真菌Xylaria sp. VDL4次级代谢产物生物合成的基因组特征及转录调控研究
Lu Li,Xiaolong Yuan,Zhonghua Chen et al.
Lu Li et al.
As a prominent group of endophytic fungi, Xylaria species have attracted considerable research interest due to their capacity to produce diverse bioactive secondary metabolites. In this study, we performed comprehensive whole-genome sequenc...
bifidoAnnotator: fine-grained annotation of bifidobacterial glycoside hydrolases for human milk glycan utilization [0.03%]
BifidoAnnotator：细粒度注释双歧杆菌糖苷水解酶以利用人类乳寡糖
Nicholas Pucci,Daniel R Mende
Nicholas Pucci
Human milk glycan (HMG) metabolism, especially by bifidobacteria, is crucial for infant gut colonization and healthy microbiome development. Bifidobacterial species and even strains are highly variable in their ability and in their enzymati...
Rolling out Plaque-2-seq: a single plaque sequencing approach enabling rapid, low-cost sequencing of phages directly from plaques [0.03%]
斑块测序（Plaque-2-seq）的推出：一种快速、低成本的直接从噬菌斑中进行噬菌体测序的方法
Slawomir Michniewski,Rebecca Glenny,Andrew Kinsella et al.
Slawomir Michniewski et al.
Rapid, accurate and scalable sequencing of bacteriophage genomes is critical to advance phage therapy, build phage biobanks and understand phage genomic diversity. Current methods are based on sequencing and assembling complete bacteriophag...
Factors contributing to the frequent interspecies transmission of G4P[6] Rotavirus alphagastroenteritidis strains from pigs to humans in Vietnam: molecular epidemiological insights [0.03%]
越南G4P[6]轮状病毒alphagastroenteritidis菌株从猪到人类频繁跨物种传播的影响因素：分子流行病学见解
Miho Kaneko,Thi Nguyen Hoa-Tran,Toyoko Nakagomi et al.
Miho Kaneko et al.
In parts of Asia, including Vietnam, Rotavirus alphagastroenteritidis (formerly known as Rotavirus A; RVA) strains of porcine origin, particularly G4P[6] strains, have been detected in humans at relatively high frequencies. This study inves...
Max L Cummins,Anne E Watt,Celeste M Donato et al.
Max L Cummins et al.
ColV/ColBM and ColIa/senB F virulence plasmids feature prominently in Escherichia coli associated with urinary tract and bloodstream infections globally. Australian-sourced E. coli that carry these plasmids were examined among 5,471 isolate...
Are the genomes of motile Aeromonas species from the aquatic environment shaped by local geography and host species? [0.03%]
水环境中运动型气单胞菌基因组是否受到当地地理环境和宿主种类的影响？
Christopher J Payne,Vo Hong Phuong,Heri Kurniawan et al.
Christopher J Payne et al.
Aeromonas dhakensis and Aeromonas hydrophila cause significant economic losses within the global aquaculture sector, affecting numerous farmed fish species and posing a zoonotic threat to human health. In this study, we sequenced, assembled...
Emergence of outbreak-driving high-risk Pseudomonas aeruginosa lineages in Taiwan: phylogenomic insights into ST292 and the ST235* sublineage [0.03%]
台湾爆发流行的高风险绿脓杆菌谱系的出现及其ST292和ST235*亚谱系的基因组见解
Chih-Ming Chen,Hui-Ling Tang,Se-Chin Ke et al.
Chih-Ming Chen et al.
The global rise of carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a significant threat to public health. Through active surveillance conducted between 2021 and 2022, we collected 92 distinct CRPA isolates and identified a clonal s...
Genome-based source attribution using a One Health Escherichia coli isolate collection from 2013 to 2023 in Scotland [0.03%]
基于基因组的来源归属：利用2013年至2023年苏格兰“同一健康”大肠杆菌分离株集合进行分析
Antonia Chalka,Louise Crozier,Adriana Vallejo-Trujillo et al.
Antonia Chalka et al.
Random forest-based source attribution models were developed from a 'One Health' resource comprising 4,230 high-quality whole-genome assemblies from Escherichia coli. These were isolated from a wide range of sources, predominantly originati...