Adaptive response to wine selective pressures shapes the genome of a Saccharomyces interspecies hybrid [0.03%]
应对葡萄酒选择压力的适应性反应塑造了萨氏氏interspecies杂交物种的基因组
María Lairón-Peris,Gabriel L Castiglioni,Sarah J Routledge et al.
María Lairón-Peris et al.
During industrial processes, yeasts are exposed to harsh conditions, which eventually lead to adaptation of the strains. In the laboratory, it is possible to use experimental evolution to link the evolutionary biology response to these adap...
Shining light on a deep-sea bacterial symbiont population structure with CRISPR [0.03%]
借助CRISPR技术揭示深海细菌内共生体种群结构
Maëva Perez,Bernard Angers,C Robert Young et al.
Maëva Perez et al.
Many foundation species in chemosynthesis-based ecosystems rely on environmentally acquired symbiotic bacteria for their survival. Hence, understanding the biogeographic distributions of these symbionts at regional scales is key to understa...
Phylum barrier and Escherichia coli intra-species phylogeny drive the acquisition of antibiotic-resistance genes [0.03%]
肠杆菌科细菌获得耐药基因的难度与其纲内系统发育距离及物种间的屏障有关关系研究
Marie Petitjean,Bénédicte Condamine,Charles Burdet et al.
Marie Petitjean et al.
Escherichia coli is a ubiquitous bacterium that has been widely exposed to antibiotics over the last 70 years. It has adapted by acquiring different antibiotic-resistance genes (ARGs), the census of which we aim to characterize here. To do ...
Ryan R Wick,Louise M Judd,Kelly L Wyres et al.
Ryan R Wick et al.
Oxford Nanopore Technologies (ONT) sequencing platforms currently offer two approaches to whole-genome native-DNA library preparation: ligation and rapid. In this study, we compared these two approaches for bacterial whole-genome sequencing...
Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova [0.03%]
摩尔多瓦基希讷ウ市耐多药结核病的起源和进化
Tyler S Brown,Vegard Eldholm,Ola Brynildsrud et al.
Tyler S Brown et al.
The evolution and emergence of drug-resistant tuberculosis (TB) has been studied extensively in some contexts, but the ecological drivers of these two processes remain poorly understood. This study sought to describe the joint evolutionary ...
Acquisition and loss of CTX-M plasmids in Shigella species associated with MSM transmission in the UK [0.03%]
与英国男男性行为者传播相关的志贺菌CTX-M质粒的获得和丢失
Rebecca K Locke,David R Greig,Claire Jenkins et al.
Rebecca K Locke et al.
Shigellosis in men who have sex with men (MSM) is caused by multidrug resistant Shigellae, exhibiting resistance to antimicrobials including azithromycin, ciprofloxacin and more recently the third-generation cephalosporins. We sequenced fou...
Genomic insights into the diversity, virulence and resistance of Klebsiella pneumoniae extensively drug resistant clinical isolates [0.03%]
泛耐药肺炎克雷伯菌基因组多样性、毒力及耐药性研究新见解
Amy H Y Lee,William F Porto,Célio de Faria Jr et al.
Amy H Y Lee et al.
Klebsiella pneumoniae has been implicated in wide-ranging nosocomial outbreaks, causing severe infections without effective treatments due to antibiotic resistance. Here, we performed genome sequencing of 70 extensively drug resistant clini...
Population genomics of transposable element activation in the highly repressive genome of an agricultural pathogen [0.03%]
农业病原体高度抑制基因组的转座元件激活的群体基因组学
Danilo Pereira,Ursula Oggenfuss,Bruce A McDonald et al.
Danilo Pereira et al.
The activity of transposable elements (TEs) can be an important driver of genetic diversity with TE-mediated mutations having a wide range of fitness consequences. To avoid deleterious effects of TE activity, some fungi have evolved highly ...
Corrigendum: Genomic evolution and local epidemiology of Klebsiella pneumoniae from a major hospital in Beijing, China, over a 15 year period: dissemination of known and novel high-risk clones [0.03%]
肺炎克雷伯菌的基因组进化及本地流行：北京一家大型医院15年期间高风险克隆体的传播及其新型高风险克隆体的出现（勘误）
Mattia Palmieri,Kelly L Wyres,Caroline Mirande et al.
Mattia Palmieri et al.
Published Erratum
Microbial genomics. 2021 Aug;7(8):000618. DOI:10.1099/mgen.0.000618 2021
The roles of antimicrobial resistance, phage diversity, isolation source and selection in shaping the genomic architecture of Bacillus anthracis [0.03%]
耐药性、噬菌体多样性、分离来源和选择在塑造炭疽芽孢杆菌基因组结构中的作用
Spencer A Bruce,Yen-Hua Huang,Pauline L Kamath et al.
Spencer A Bruce et al.
Bacillus anthracis, the causative agent of anthrax disease, is a worldwide threat to livestock, wildlife and public health. While analyses of genetic data from across the globe have increased our understanding of this bacterium’s populatio...