Identification of novel, cryptic Clostridioides species isolates from environmental samples collected from diverse geographical locations [0.03%]
从不同地理位置采集的环境样本中鉴定出新型隐秘的拟杆菌属物种分离株
Charles Hall Davis Williamson,Nathan E Stone,Amalee E Nunnally et al.
Charles Hall Davis Williamson et al.
Clostridioides difficile is a pathogen often associated with hospital-acquired infection or antimicrobial-induced disease; however, increasing evidence indicates infections can result from community or environmental sources. Most genomic se...
Occurrence of genes encoding spore germination in Clostridium species that cause meat spoilage [0.03%]
引起肉变质的梭菌属物种孢子萌发编码基因的存在性
Sara A Burgess,Faith P Palevich,Amanda Gardner et al.
Sara A Burgess et al.
Members of the genus Clostridium are frequently associated with meat spoilage. The ability for low numbers of spores of certain Clostridium species to germinate in cold-stored vacuum-packed meat can result in blown pack spoilage. However, l...
Reciprocally rewiring and repositioning the Integration Host Factor (IHF) subunit genes in Salmonella enterica serovar Typhimurium: impacts on physiology and virulence [0.03%]
利用鼠伤寒沙门氏菌（Salmonella Enterica Serovar Typhimurium）互换和重新定位整合宿主因子(IHF)亚基基因对生理及毒力的影响
German Pozdeev,Michael C Beckett,Aalap Mogre et al.
German Pozdeev et al.
The Integration Host Factor (IHF) is a heterodimeric nucleoid-associated protein that plays roles in bacterial nucleoid architecture and genome-wide gene regulation. The ihfA and ihfB genes encode the subunits and are located 350 kbp apart,...
Genomic and phenotypic analyses of diverse non-clinical Acinetobacter baumannii strains reveals strain-specific virulence and resistance capacity [0.03%]
对多种非临床来源的鲍曼不动杆菌菌株进行基因组和表型分析，揭示了特定菌株的毒力和耐药能力
Mohammad Hamidian,Ram P Maharjan,Daniel N Farrugia et al.
Mohammad Hamidian et al.
Acinetobacter baumannii is a critically important pathogen known for its widespread antibiotic resistance and ability to persist in hospital-associated environments. Whilst the majority of A. baumannii infections are hospital-acquired, infe...
Genomic analysis reveals high intra-species diversity of Shewanella algae [0.03%]
基因组分析揭示Shewanella algae的高种内多样性
Zhenzhou Huang,Keyi Yu,Songzhe Fu et al.
Zhenzhou Huang et al.
Shewanella algae is widely distributed in marine and freshwater habitats, and has been proved to be an emerging marine zoonotic and human pathogen. However, the genomic characteristics and pathogenicity of Shewanella algae are unclear. Here...
Towards comprehensive understanding of bacterial genetic diversity: large-scale amplifications in Bordetella pertussis and Mycobacterium tuberculosis [0.03%]
从整体上理解细菌遗传多样性：百日咳杆菌和结核分支杆菌的大规模扩增
Jonathan S Abrahams,Michael R Weigand,Natalie Ring et al.
Jonathan S Abrahams et al.
Bacterial genetic diversity is often described solely using base-pair changes despite a wide variety of other mutation types likely being major contributors. Tandem duplication/amplifications are thought to be widespread among bacteria but ...
Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints [0.03%]
肺炎链球菌在非洲农村地区的广泛传播：邻近村庄更有可能共享在同一时间点携带的相似菌株
Madikay Senghore,Chrispin Chaguza,Ebrima Bojang et al.
Madikay Senghore et al.
The transmission dynamics of Streptococcus pneumoniae in sub-Saharan Africa are poorly understood due to a lack of adequate epidemiological and genomic data. Here we leverage a longitudinal cohort from 21 neighbouring villages in rural Afri...
Multi-laboratory evaluation of the Illumina iSeq platform for whole genome sequencing of Salmonella, Escherichia coli and Listeria [0.03%]
Illumina iSeq平台的多实验室评估用于沙门氏菌、大肠杆菌和李斯特菌全基因组测序
Patrick K Mitchell,Leyi Wang,Bryce J Stanhope et al.
Patrick K Mitchell et al.
There is a growing need for public health and veterinary laboratories to perform whole genome sequencing (WGS) for monitoring antimicrobial resistance (AMR) and protecting the safety of people and animals. With the availability of smaller a...
Genomic diversity and antimicrobial resistance of Prevotella species isolated from chronic lung disease airways [0.03%]
来自慢性肺病气道的普氏菌种的基因组多样性及抗微生物药物耐药性
Kasey A Webb,Olusola Olagoke,Timothy Baird et al.
Kasey A Webb et al.
Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are characterized by increasingly frequent acute pulmonary exacerbations that reduce life quality and length. Human airways are home to a rich polymicrobial environment, ...
Diversity of carbapenem-resistant Acinetobacter baumannii and bacteriophage-mediated spread of the Oxa23 carbapenemase [0.03%]
碳青霉烯耐药的阿氏不动杆菌基因型多样性及含有OXA-23酶的噬菌体介导的传播
Alaa Abouelfetouh,Jennifer Mattock,Dann Turner et al.
Alaa Abouelfetouh et al.
Carbapenem-resistant Acinetobacter baumannii are prevalent in low- and middle-income countries such as Egypt, but little is known about the molecular epidemiology and mechanisms of resistance in these settings. Here, we characterize carbape...