Stop codon reassignment to tryptophan in members of the bacterial phylum Actinomycetota [0.03%]
放线菌门细菌中终止密码子重分配为色氨酸的现象
Donovan H Parks,Pierre-Alain Chaumeil,Maria Chuvochina et al.
Donovan H Parks et al.
Reassignment of stop codons is a significant evolutionary event with recoding of UGA to tryptophan being previously identified in only three bacterial phyla, the Bacillota, Pseudomonadota and Verrucomicrobiota. Here, we present genomic evid...
Genomic diversity of Pseudomonas aeruginosa causing bacteremic pneumonia in an intensive care unit, with emergence of an OXA-796-producing NDM-1 ST773 isolate [0.03%]
产金属β内酰胺酶NDM-1ST773型别携带OXA-796基因的绿脓杆菌血流感染菌株的基因组多样性研究
Kihyun Lee,Hyemin Chung,Kuenyoul Park et al.
Kihyun Lee et al.
Pseudomonas aeruginosa bacteremic pneumonia carries exceptionally high mortality, yet there is a paucity of genomic characterization of the strains causing this infection. We performed hybrid sequencing (Illumina and Oxford Nanopore) of 12 ...
The genome, transcriptome and metabolome of Aspergillus welwitschiae Ocstreb1 from wild halophytic rice, Oryza coarctata, indicates its distinctiveness [0.03%]
采自野生盐生稻(Oryza coarctata)的曲霉菌(Asergillus welwitschiae Ocstreb1)的基因组、转录组和代谢组表明其独特性
Nishat Tamanna,Md Nafis Ul Alam,Arifa Akhter Airin et al.
Nishat Tamanna et al.
Aspergillus welwitschiae is a widespread fungus with diverse roles as a plant mutualist, opportunistic human pathogen and industrial enzyme producer. The endophytic strain AwOcstreb1, isolated from halophytic rice (Oryza coarctata), promote...
Integrated poultry production as a reservoir of tet(X4) and mcr-1.1 encoding Escherichia coli in Pakistan [0.03%]
我国巴基斯坦禽类综合养殖业中产生四环素耐药基因tet(X4和黏菌素耐药基因mcr-1.1的大肠埃希菌的存储库
Muhammad Ahmed Mushtaq,Peter Schierack,Muhammad Yousaf et al.
Muhammad Ahmed Mushtaq et al.
Plasmid-mediated colistin and tigecycline resistance threatens last-resort therapeutic options. We investigated the farm-to-fork dissemination of Escherichia coli encoding mcr-1.1 and tet(X4) in a vertically integrated broiler production sy...
Ishaq O Balogun,Christopher P Mancuso,Tami D Lieberman
Ishaq O Balogun
Traditional methods for identifying associations between genomic features and traits, or between pairs of genomic traits, struggle when applied to bacterial genomes. While several microbial genome-wide association study (mGWAS) methods have...
Phylogenetic analysis of serotype 19A-sequence type (ST)2331 Streptococcus pneumoniae associated with the Pneumococcal Molecular Epidemiology Network (PMEN)34 clone predominant in Japan after the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) [0.03%]
肺炎链球菌序系(ST)2331血清型19A的系统发育分析与肺炎链球菌分子流行病学网络(PMEN)34克隆株在日本引入7价肺炎球菌结合疫苗(PCV7)后的流行有关
Shota Koide,Satoshi Nakano,Takao Fujisawa et al.
Shota Koide et al.
Following the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7), serotype 19A Streptococcus pneumoniae emerged as a major cause of paediatric pneumococcal disease in Japan. Unlike global trends, in which multidrug-resistant...
Mitogenomics in Amanita, evolution, species delimitation and its utility at the species complex level [0.03%]
阿манита子囊菌的线粒体基因组学：演化、物种界定及其在物种复合群中的应用价值
Christian Quintero-Corrales,Roberto Garibay-Orijel
Christian Quintero-Corrales
Mitochondrial genomes are among the most powerful sources for resolving evolutionary relationships in eukaryotes; however, their application in fungal phylogenetics remains underutilized. In this study, we employed comparative genomics and ...
Integrating genomic and transcriptomic analyses reveals virulence factors and bloodstream infection mechanisms of Acinetobacter junii [0.03%]
整合基因组和转录组分析揭示了阿氏不动杆菌毒力因子和菌血症感染机制
Chenlu Xiao,Shuo Jiang,Zhenwei Guo et al.
Chenlu Xiao et al.
Acinetobacter junii, an emerging pathogen of the Acinetobacter genus, exhibits concerning environmental persistence and clinical virulence potential. Despite its growing significance in bloodstream infections (BSIs), the genetic determinant...
Whole-genome sequencing of Staphylococcus capitis isolates from neonates with healthcare-associated bacteraemia in neonatal intensive care units in Taiwan: comparison between the NRCS-A strain and a non-NRCS-A multi-resistant strain [0.03%]
台湾NICU中新生儿卫生保健相关菌血症的Staphylococcus capitis分离株全基因组测序：NRCS-A型与多重耐药非NRCS-A型的比较
Yu-Rou Yeh,Yi-Hsuan Huang,Chih-Jung Chen et al.
Yu-Rou Yeh et al.
Staphylococcus capitis is a common pathogen causing late-onset sepsis in neonatal intensive care units (NICUs). A specific clone, S. capitis NRCS-A, which was first reported in 2012 from France, is spreading globally in NICU settings. The p...
Comparative Study
Microbial genomics. 2026 Jul;12(7). DOI:10.1099/mgen.0.001798 2026
Benchmarking of real-time, field-deployable whole-genome sequencing of Plasmodium falciparum using Nanopore technology [0.03%]
基于纳米孔技术的实时现场全流程测序评估恶性疟原虫基因组质量研究
Zahra Razook,Somya Mehra,Myo T Naung et al.
Zahra Razook et al.
Malaria parasite genomes have been generated predominantly using Illumina short-read sequencing that requires expensive equipment, is time-consuming with complex protocols, and does not adequately interrogate complex genomic regions that ha...