Cold atmospheric plasma ameliorating skin barrier in chronic kidney disease [0.03%]
冷等离子体改善慢性肾脏病皮肤屏障功能
Meng Wang,Hongli Jiang,Dingxin Liu et al.
Meng Wang et al.
Chronic kidney disease (CKD)-associated skin complications, including pruritus and xerosis, remain clinically challenging due to poorly understood pathological mechanisms. We utilized human skin tissues, adenine-induced CKD mice, and HaCaT ...
The SHEDs-derived apoptotic bodies for inflammatory regulation in spinal cord repair [0.03%]
一种用于脊髓修复的炎症调节因子：源自SHEDs的凋亡小体
Lihua Luo,Na Dong,Junpeng Xu et al.
Lihua Luo et al.
Neuroinflammation is a key therapeutic target for spinal cord injury (SCI). Apoptotic bodies (ABs) derived from mesenchymal stem cells may modulate early inflammation, promoting SCI repair. Stem cells from human exfoliated deciduous teeth (...
A modified bacterial nanocellulose-based advanced therapy product accelerates third-degree burn healing in murine models [0.03%]
一种改良细菌纳米纤维素基先进治疗产品可加速小鼠三度烧伤的愈合
Manuella Machado Godoi,Caroline Portela Peruzzi,Joao Vitor Alves Hoepers et al.
Manuella Machado Godoi et al.
Severe burn injuries represent a major global healthcare burden, with high costs and prolonged hospitalizations. Current treatments, including autologous skin grafting, are limited by donor availability, while allografts carry risks of immu...
Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko [0.03%]
豹纹守宫心室再生
Kathy Jacyniak,Catherine J A Williams,Hugues Beaufrère et al.
Kathy Jacyniak et al.
Among mammals, injury to the heart typically results in scar formation and diminished cardiovascular function. In contrast, some teleost fish and salamanders can replace damaged heart tissue and restore overall function. For most species, h...
Three-dimensional models of skeletal muscle under tension: a systematic review and core outcome set [0.03%]
张力作用下的骨骼肌三维模型的系统综述及核心结果变量集
Kunal Bhanot;Core Outcome Set Review Group;Neal Thurley,Robin O Cleveland,Jolet Mimpen et al.
Kunal Bhanot;Core Outcome Set Review Group;Neal Thurley et al.
Biologically representative three-dimensional (3D) skeletal muscle models are required to understand the mechanisms underpinning muscle disease. The primary aim of this systematic review is to evaluate the current literature on 3D skeletal ...
Author Correction: Disease exacerbation in human DMD MYOrganoids enables gene therapy evaluation and unveils persistence of fibrotic activity [0.03%]
作者更正：人类DMD MY器官体内的疾病加重可使基因治疗评估并揭示纤维活性的持续存在
Laura Palmieri,Giorgia Bimbi,Maxime Ferrand et al.
Laura Palmieri et al.
Published Erratum
NPJ Regenerative medicine. 2026 Apr 14;11(1):19. DOI:10.1038/s41536-026-00474-x 2026
Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche [0.03%]
小鼠毛囊微环境中黑色素干细胞静息和激活的边界解析
Tatsuya Ogawa,Min Chen,Soung-Hoon Lee et al.
Tatsuya Ogawa et al.
Melanocyte stem cells (McSCs) are a crucial melanocyte reservoir within the hair follicle niche. This review provides an overview of the processes for McSC quiescence and activation. Because McSCs closely interact with hair follicle stem ce...
CellCousin2: an optimized system for partial ablation and tracing of regenerative lineages [0.03%]
细胞堂兄弟2号：优化的再生谱系部分消融和追踪系统
Gabriel Garnik Hovhannisyan,Tawba Akhourbi,Sema Elif Eski et al.
Gabriel Garnik Hovhannisyan et al.
Regeneration can rely on multiple cellular sources, including stem cells, self-duplicating cells, and transdifferentiating cells. A central question in regenerative biology is how these distinct lineages contribute to repair and interact wi...
A characterization of axolotl digit regeneration: conserved mechanisms, divergent patterning, and a critical role for hedgehog signaling [0.03%]
一种墨西哥钝口螈肢体再生机制的研究：保守的再生机制、多样的模式形成以及 Hedgehog 信号途径的关键作用
Jackson R Griffiths,Melissa Miller,Timothy J Duerr et al.
Jackson R Griffiths et al.
Axolotl digits offer an experimentally versatile model for studying complex tissue regeneration. Here, we provide a comprehensive morphological and molecular characterization of digit regeneration, revealing both conserved features and nota...
Wnt-presenting materials sustain H3K14-acetylation in human skeletal stem cells for tissue engineering and bone repair [0.03%]
用于组织工程和骨修复的人类骨骼干细胞H3K14乙酰化的Wnt呈递材料
Pierre Becquart,Pierre Tournier,Sergi Junyent et al.
Pierre Becquart et al.
Engineering functional tissues for transplantation requires insight into epigenetic mechanisms that regulate stem cell fate. We have developed the Wnt-induced osteogenic tissue model (WIOTM), a platform that recapitulates human osteogenesis...