Impaired bone healing upon neutrophil-specific adrenoreceptor beta 2 knockout in non-osteoporotic and osteoporotic mice [0.03%]
非骨质疏松小鼠和骨质疏松小鼠中特异性敲除中性粒细胞肾上腺素能受体β2后骨骼愈合受损
Sandra Dieterich,Nico Gläser,Christoph Kölbl et al.
Sandra Dieterich et al.
After a bone fracture, osteoporotic mice show delayed healing associated with elevated systemic inflammation and increased neutrophil numbers in the early fracture hematoma. Because short-term treatment with the beta-adrenoreceptor-blocker ...
Author Correction: Parishin A-loaded mesoporous silica nanoparticles modulate macrophage polarization to attenuate tendinopathy [0.03%]
作者更正：负载了帕瑞辛的介孔二氧化硅纳米颗粒可调节巨噬细胞极化以减轻肌腱病
Lisha Zhu,Yu Wang,Shanshan Jin et al.
Lisha Zhu et al.
Published Erratum
NPJ Regenerative medicine. 2026 May 28;11(1):25. DOI:10.1038/s41536-026-00480-z 2026
Samantha Kruzshak,Flannery G Williams,Gulden Camci-Unal et al.
Samantha Kruzshak et al.
Pancreatic β-cell dysfunction causes diabetes in over 400 million worldwide. Islet transplantation promises but faces donor scarcity, rejection, and hypoxic failure. β cells are vulnerable to oxygen deprivation, affecting survival and fun...
Paxillin in mechanosensitive spatial control of lung endothelial cell regeneration [0.03%]
肺内皮细胞再生中力学敏感的paxillin空间调控作用
Tadanori Mammoto,Priscilla Kyi,Mikaela Scheer et al.
Tadanori Mammoto et al.
Mechanical forces altered after unilateral pneumonectomy (PNX) control post-PNX lung growth. Here, we demonstrate that post-PNX endothelial regeneration is stimulated at the peripheral region of the mouse lung, requiring the focal adhesion ...
Interventions and platforms that direct lymphangiogenesis to restore physiological homeostasis and enhance immunoregulation [0.03%]
干预措施和平台通过引导淋巴管生成来恢复生理稳态和增强免疫调节
Lauren G Porter,Mikayla S Jackson,Robert S Oakes
Lauren G Porter
The lymphatic system maintains physiological homeostasis through constant immunosurveillance, immune cell trafficking, and regulation of interstitial fluid flow. Lymphatic dysfunction is associated with a wide range of pathologies, includin...
Cold atmospheric plasma ameliorating skin barrier in chronic kidney disease [0.03%]
冷等离子体改善慢性肾脏病皮肤屏障功能
Meng Wang,Hongli Jiang,Dingxin Liu et al.
Meng Wang et al.
Chronic kidney disease (CKD)-associated skin complications, including pruritus and xerosis, remain clinically challenging due to poorly understood pathological mechanisms. We utilized human skin tissues, adenine-induced CKD mice, and HaCaT ...
The SHEDs-derived apoptotic bodies for inflammatory regulation in spinal cord repair [0.03%]
一种用于脊髓修复的炎症调节因子：源自SHEDs的凋亡小体
Lihua Luo,Na Dong,Junpeng Xu et al.
Lihua Luo et al.
Neuroinflammation is a key therapeutic target for spinal cord injury (SCI). Apoptotic bodies (ABs) derived from mesenchymal stem cells may modulate early inflammation, promoting SCI repair. Stem cells from human exfoliated deciduous teeth (...
A modified bacterial nanocellulose-based advanced therapy product accelerates third-degree burn healing in murine models [0.03%]
一种改良细菌纳米纤维素基先进治疗产品可加速小鼠三度烧伤的愈合
Manuella Machado Godoi,Caroline Portela Peruzzi,Joao Vitor Alves Hoepers et al.
Manuella Machado Godoi et al.
Severe burn injuries represent a major global healthcare burden, with high costs and prolonged hospitalizations. Current treatments, including autologous skin grafting, are limited by donor availability, while allografts carry risks of immu...
Heart ventricle regeneration in the lizard Eublepharis macularius, the leopard gecko [0.03%]
豹纹守宫心室再生
Kathy Jacyniak,Catherine J A Williams,Hugues Beaufrère et al.
Kathy Jacyniak et al.
Among mammals, injury to the heart typically results in scar formation and diminished cardiovascular function. In contrast, some teleost fish and salamanders can replace damaged heart tissue and restore overall function. For most species, h...
Three-dimensional models of skeletal muscle under tension: a systematic review and core outcome set [0.03%]
张力作用下的骨骼肌三维模型的系统综述及核心结果变量集
Kunal Bhanot;Core Outcome Set Review Group;Neal Thurley,Robin O Cleveland,Jolet Mimpen et al.
Kunal Bhanot;Core Outcome Set Review Group;Neal Thurley et al.
Biologically representative three-dimensional (3D) skeletal muscle models are required to understand the mechanisms underpinning muscle disease. The primary aim of this systematic review is to evaluate the current literature on 3D skeletal ...